Literature DB >> 6774257

An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing.

W Dunnick, T H Rabbitts, C Milstein.   

Abstract

The IF2 immunoglobulin mutant is a DNA deletion of one coding segment and large sections of the flanking intervening sequences. The deletion results in a new splicing pattern and starts in a DNA region containing tandemly repeated sequences which may carry heavy-chain class switch signals.

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Year:  1980        PMID： 6774257     DOI： 10.1038/286669a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  47 in total

1.  Variable deletion and duplication at recombination junction ends: implication for staggered double-strand cleavage in class-switch recombination.

Authors:  X Chen; K Kinoshita; T Honjo
Journal:  Proc Natl Acad Sci U S A       Date:  2001-11-20       Impact factor: 11.205

2.  Genetic test for involvement of intervening sequences in transport of nuclear RNA.

Authors:  L P Villarreal; S Carr
Journal:  Mol Cell Biol       Date:  1982-12       Impact factor: 4.272

3.  Copy choice mechanism of immunoglobulin heavy-chain switch recombination.

Authors:  W Dunnick; J Stavnezer
Journal:  Mol Cell Biol       Date:  1990-01       Impact factor: 4.272

4.  Unique sequences are interspersed among tandemly repeated elements in the murine gamma 1 switch segment.

Authors:  M Mowatt; C Dery; W Dunnick
Journal:  Nucleic Acids Res       Date:  1985-01-11       Impact factor: 16.971

5.  Mechanisms of nonhomologous recombination in mammalian cells.

Authors:  D B Roth; T N Porter; J H Wilson
Journal:  Mol Cell Biol       Date:  1985-10       Impact factor: 4.272

Review 6.  Regulation of AID, the B-cell genome mutator.

Authors:  Celia Keim; David Kazadi; Gerson Rothschild; Uttiya Basu
Journal:  Genes Dev       Date:  2013-01-01       Impact factor: 11.361

Review 7.  Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.

Authors:  Allysia J Matthews; Simin Zheng; Lauren J DiMenna; Jayanta Chaudhuri
Journal:  Adv Immunol       Date:  2014       Impact factor: 3.543

8.  A DNA insertion/deletion necessitates an aberrant RNA splice accounting for a mu heavy chain disease protein.

Authors:  A Bakhshi; P Guglielmi; U Siebenlist; J V Ravetch; J P Jensen; S J Korsmeyer
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205

9.  Presence of albumin mRNA precursors in nuclei of analbuminemic rat liver lacking cytoplasmic albumin mRNA.

Authors:  H Esumi; Y Takahashi; T Sekiya; S Sato; S Nagase; T Sugimura
Journal:  Proc Natl Acad Sci U S A       Date:  1982-02       Impact factor: 11.205

10.  Cloned embryonic DNA sequences flanking the mouse immunoglobulin C gamma 3 and C gamma 1 genes.

Authors:  J M Adams; E Webb; S Gerondakis; S Cory
Journal:  Nucleic Acids Res       Date:  1980-12-20       Impact factor: 16.971
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