Literature DB >> 20955924

The psychiatric GWAS consortium: big science comes to psychiatry.

Patrick F Sullivan1.   

Abstract

The Psychiatric GWAS Consortium was founded with the aim of conducting statistically rigorous and comprehensive GWAS meta-analyses for five major psychiatric disorders: ADHD, autism, bipolar disorder, major depressive disorder, and schizophrenia. In the era of GWAS and high-throughput genomics, a major trend has been the emergence of collaborative, consortia approaches. Taking advantage of the scale that collaborative consortia approaches can bring to a problem, the PGC has been a major driver in psychiatric genetics and provides a model for how similar approaches may be applied to other disease communities.
Copyright © 2010 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Year:  2010        PMID： 20955924      PMCID： PMC2991765          DOI： 10.1016/j.neuron.2010.10.003

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  22 in total

1.  Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.

Authors:  D H Blackwood; A Fordyce; M T Walker; D M St Clair; D J Porteous; W J Muir
Journal:  Am J Hum Genet       Date:  2001-07-06       Impact factor: 11.025

Review 2.  Clinical validity.

Authors:  R E Kendell
Journal:  Psychol Med       Date:  1989-02       Impact factor: 7.723

3.  Replicating genotype-phenotype associations.

Authors:  Stephen J Chanock; Teri Manolio; Michael Boehnke; Eric Boerwinkle; David J Hunter; Gilles Thomas; Joel N Hirschhorn; Goncalo Abecasis; David Altshuler; Joan E Bailey-Wilson; Lisa D Brooks; Lon R Cardon; Mark Daly; Peter Donnelly; Joseph F Fraumeni; Nelson B Freimer; Daniela S Gerhard; Chris Gunter; Alan E Guttmacher; Mark S Guyer; Emily L Harris; Josephine Hoh; Robert Hoover; C Augustine Kong; Kathleen R Merikangas; Cynthia C Morton; Lyle J Palmer; Elizabeth G Phimister; John P Rice; Jerry Roberts; Charles Rotimi; Margaret A Tucker; Kyle J Vogan; Sholom Wacholder; Ellen M Wijsman; Deborah M Winn; Francis S Collins
Journal:  Nature       Date:  2007-06-07       Impact factor: 49.962

4.  The NCBI dbGaP database of genotypes and phenotypes.

Authors:  Matthew D Mailman; Michael Feolo; Yumi Jin; Masato Kimura; Kimberly Tryka; Rinat Bagoutdinov; Luning Hao; Anne Kiang; Justin Paschall; Lon Phan; Natalia Popova; Stephanie Pretel; Lora Ziyabari; Moira Lee; Yu Shao; Zhen Y Wang; Karl Sirotkin; Minghong Ward; Michael Kholodov; Kerry Zbicz; Jeffrey Beck; Michael Kimelman; Sergey Shevelev; Don Preuss; Eugene Yaschenko; Alan Graeff; James Ostell; Stephen T Sherry
Journal:  Nat Genet       Date:  2007-10       Impact factor: 38.330

5.  Guilt beyond a reasonable doubt.

Authors:  David Altshuler; Mark Daly
Journal:  Nat Genet       Date:  2007-07       Impact factor: 38.330

6.  Estimation of the multiple testing burden for genomewide association studies of nearly all common variants.

Authors:  Itsik Pe'er; Roman Yelensky; David Altshuler; Mark J Daly
Journal:  Genet Epidemiol       Date:  2008-05       Impact factor: 2.135

7.  How to interpret a genome-wide association study.

Authors:  Thomas A Pearson; Teri A Manolio
Journal:  JAMA       Date:  2008-03-19       Impact factor: 56.272

8.  New models of collaboration in genome-wide association studies: the Genetic Association Information Network.

Authors:  Teri A Manolio; Laura Lyman Rodriguez; Lisa Brooks; Gonçalo Abecasis; Dennis Ballinger; Mark Daly; Peter Donnelly; Stephen V Faraone; Kelly Frazer; Stacey Gabriel; Pablo Gejman; Alan Guttmacher; Emily L Harris; Thomas Insel; John R Kelsoe; Eric Lander; Norma McCowin; Matthew D Mailman; Elizabeth Nabel; James Ostell; Elizabeth Pugh; Stephen Sherry; Patrick F Sullivan; John F Thompson; James Warram; David Wholley; Patrice M Milos; Francis S Collins
Journal:  Nat Genet       Date:  2007-09       Impact factor: 38.330

Review 9.  The positives, protocols, and perils of genome-wide association.

Authors:  Benjamin M Neale; Shaun Purcell
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2008-10-05       Impact factor: 3.568

Review 10.  Rare structural variants in schizophrenia: one disorder, multiple mutations; one mutation, multiple disorders.

Authors:  Jonathan Sebat; Deborah L Levy; Shane E McCarthy
Journal:  Trends Genet       Date:  2009-10-31       Impact factor: 11.639
View more
  106 in total

Review 1.  Genetic architectures of psychiatric disorders: the emerging picture and its implications.

Authors:  Patrick F Sullivan; Mark J Daly; Michael O'Donovan
Journal:  Nat Rev Genet       Date:  2012-07-10       Impact factor: 53.242

2.  Quality control, imputation and analysis of genome-wide genotyping data from the Illumina HumanCoreExome microarray.

Authors:  Jonathan R I Coleman; Jack Euesden; Hamel Patel; Amos A Folarin; Stephen Newhouse; Gerome Breen
Journal:  Brief Funct Genomics       Date:  2015-10-05       Impact factor: 4.241

3.  Psychiatric genetics in China: achievements and challenges.

Authors:  Chunyu Liu; David Saffen; Thomas G Schulze; Margit Burmeister; Pak Chung Sham; Yong-Gang Yao; Po-Hsiu Kuo; Chao Chen; Yu An; Jiapei Dai; Weihua Yue; Miao Xin Li; Hong Xue; Bing Su; Li Chen; Yongyong Shi; Mingqi Qiao; Tiebang Liu; Kun Xia; Raymond C K Chan
Journal:  Mol Psychiatry       Date:  2015-10-20       Impact factor: 15.992

Review 4.  The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: Posttraumatic Stress Disorder Enters the Age of Large-Scale Genomic Collaboration.

Authors:  Mark W Logue; Ananda B Amstadter; Dewleen G Baker; Laramie Duncan; Karestan C Koenen; Israel Liberzon; Mark W Miller; Rajendra A Morey; Caroline M Nievergelt; Kerry J Ressler; Alicia K Smith; Jordan W Smoller; Murray B Stein; Jennifer A Sumner; Monica Uddin
Journal:  Neuropsychopharmacology       Date:  2015-04-23       Impact factor: 7.853

Review 5.  Gene expression profiling of the brain: pondering facts and fiction.

Authors:  Amanda C Mitchell; Károly Mirnics
Journal:  Neurobiol Dis       Date:  2011-06-14       Impact factor: 5.996

6.  Adverse life events, psychiatric history, and biological predictors of postpartum depression in an ethnically diverse sample of postpartum women.

Authors:  J Guintivano; P F Sullivan; A M Stuebe; T Penders; J Thorp; D R Rubinow; S Meltzer-Brody
Journal:  Psychol Med       Date:  2017-09-27       Impact factor: 7.723

Review 7.  Genetic determinants of depression: recent findings and future directions.

Authors:  Erin C Dunn; Ruth C Brown; Yael Dai; Jonathan Rosand; Nicole R Nugent; Ananda B Amstadter; Jordan W Smoller
Journal:  Harv Rev Psychiatry       Date:  2015 Jan-Feb       Impact factor: 3.732

Review 8.  Precision medicine and pharmacogenetics: what does oncology have that addiction medicine does not?

Authors:  Henry R Kranzler; Rachel V Smith; Robert Schnoll; Afaf Moustafa; Emma Greenstreet-Akman
Journal:  Addiction       Date:  2017-04-21       Impact factor: 6.526

9.  Polygenic risk, stressful life events and depressive symptoms in older adults: a polygenic score analysis.

Authors:  K L Musliner; F Seifuddin; J A Judy; M Pirooznia; F S Goes; P P Zandi
Journal:  Psychol Med       Date:  2014-12-09       Impact factor: 7.723

Review 10.  Bringing a developmental perspective to anxiety genetics.

Authors:  Lauren M McGrath; Sydney Weill; Elise B Robinson; Rebecca Macrae; Jordan W Smoller
Journal:  Dev Psychopathol       Date:  2012-11
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.