Literature DB >> 17728769

New models of collaboration in genome-wide association studies: the Genetic Association Information Network.

Teri A Manolio, Laura Lyman Rodriguez, Lisa Brooks, Gonçalo Abecasis, Dennis Ballinger, Mark Daly, Peter Donnelly, Stephen V Faraone, Kelly Frazer, Stacey Gabriel, Pablo Gejman, Alan Guttmacher, Emily L Harris, Thomas Insel, John R Kelsoe, Eric Lander, Norma McCowin, Matthew D Mailman, Elizabeth Nabel, James Ostell, Elizabeth Pugh, Stephen Sherry, Patrick F Sullivan, John F Thompson, James Warram, David Wholley, Patrice M Milos, Francis S Collins.   

Abstract

The Genetic Association Information Network (GAIN) is a public-private partnership established to investigate the genetic basis of common diseases through a series of collaborative genome-wide association studies. GAIN has used new approaches for project selection, data deposition and distribution, collaborative analysis, publication and protection from premature intellectual property claims. These demonstrate a new commitment to shared scientific knowledge that should facilitate rapid advances in understanding the genetics of complex diseases.

Mesh:

Year:  2007        PMID: 17728769     DOI: 10.1038/ng2127

Source DB:  PubMed          Journal:  Nat Genet        ISSN: 1061-4036            Impact factor:   38.330


  163 in total

Review 1.  The tension between data sharing and the protection of privacy in genomics research.

Authors:  Jane Kaye
Journal:  Annu Rev Genomics Hum Genet       Date:  2012-03-09       Impact factor: 8.929

2.  A quality control algorithm for filtering SNPs in genome-wide association studies.

Authors:  Monnat Pongpanich; Patrick F Sullivan; Jung-Ying Tzeng
Journal:  Bioinformatics       Date:  2010-05-25       Impact factor: 6.937

Review 3.  Approaching biomarker discovery through genomics.

Authors:  Stephen S Rich
Journal:  J Cardiovasc Transl Res       Date:  2008-01-26       Impact factor: 4.132

4.  Spoiling the whole bunch: quality control aimed at preserving the integrity of high-throughput genotyping.

Authors:  Anna Pluzhnikov; Jennifer E Below; Anuar Konkashbaev; Anna Tikhomirov; Emily Kistner-Griffin; Cheryl A Roe; Dan L Nicolae; Nancy J Cox
Journal:  Am J Hum Genet       Date:  2010-07-09       Impact factor: 11.025

5.  Statistical genetic issues for genome-wide association studies.

Authors:  Bruce S Weir
Journal:  Genome       Date:  2010-11       Impact factor: 2.166

6.  Introduction of Francis S. Collins.

Authors:  David Ginsburg
Journal:  J Clin Invest       Date:  2015-08-17       Impact factor: 14.808

7.  Phenotype harmonization and cross-study collaboration in GWAS consortia: the GENEVA experience.

Authors:  Siiri N Bennett; Neil Caporaso; Annette L Fitzpatrick; Arpana Agrawal; Kathleen Barnes; Heather A Boyd; Marilyn C Cornelis; Nadia N Hansel; Gerardo Heiss; John A Heit; Jae Hee Kang; Steven J Kittner; Peter Kraft; William Lowe; Mary L Marazita; Kristine R Monroe; Louis R Pasquale; Erin M Ramos; Rob M van Dam; Jenna Udren; Kayleen Williams
Journal:  Genet Epidemiol       Date:  2011-01-31       Impact factor: 2.135

8.  Non-random error in genotype calling procedures: implications for family-based and case-control genome-wide association studies.

Authors:  Richard J L Anney; Elaine Kenny; Colm T O'Dushlaine; Jessica Lasky-Su; Barbara Franke; Derek W Morris; Benjamin M Neale; Philip Asherson; Stephen V Faraone; Michael Gill
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2008-12-05       Impact factor: 3.568

Review 9.  ADHD and smoking: from genes to brain to behavior.

Authors:  Francis Joseph McClernon; Scott Haden Kollins
Journal:  Ann N Y Acad Sci       Date:  2008-10       Impact factor: 5.691

Review 10.  Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify "connectivity constellation" and drug target genes with pleiotropic effects.

Authors:  George R Uhl; Tomas Drgon; Catherine Johnson; Chuan-Yun Li; Carlo Contoreggi; Judith Hess; Daniel Naiman; Qing-Rong Liu
Journal:  Ann N Y Acad Sci       Date:  2008-10       Impact factor: 5.691

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