| Literature DB >> 20946812 |
Sean R Collins1, Assen Roguev, Nevan J Krogan.
Abstract
Genetic interactions represent the degree to which the presence of one mutation modulates the phenotype of a second mutation. In recent years, approaches for measuring genetic interactions systematically and quantitatively have proven to be effective tools for unbiased characterization of gene function and have provided valuable data for analyses of evolution. Here, we present protocols for systematic measurement of genetic interactions with respect to organismal growth rate for two yeast species.Entities:
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Year: 2010 PMID: 20946812 PMCID: PMC2957675 DOI: 10.1016/S0076-6879(10)70009-4
Source DB: PubMed Journal: Methods Enzymol ISSN: 0076-6879 Impact factor: 1.600