Literature DB >> 20888199

Flattening filter free beams in SBRT and IMRT: dosimetric assessment of peripheral doses.

Gabriele Kragl1, Franziska Baier, Steffen Lutz, David Albrich, Mårten Dalaryd, Bernhard Kroupa, Tilo Wiezorek, Tommy Knöös, Dietmar Georg.   

Abstract

PURPOSE: Recently, there has been a growing interest in operating medical linear accelerators without a flattening filter. Due to reduced scatter, leaf transmission and radiation head leakage a reduction of out-of-field dose is expected for flattening filter free beams. The aim of the present study was to determine the impact of unflattened beams on peripheral dose for advanced treatment techniques with a large number of MUs.
MATERIAL AND METHODS: An Elekta Precise linac was modified to provide 6 and 10 MV photon beams without a flattening filter. Basic beam data were collected and implemented into the TPS Oncentra Masterplan (Nucletron). Leakage radiation, which predominantly contributes to peripheral dose at larger distances from the field edge, was measured using a Farmer type ionisation chamber. SBRT (lung) and IMRT (prostate, head&neck) treatment plans were generated for 6 and 10 MV for both flattened and unflattened beams. All treatment plans were delivered to the relevant anatomic region of an anthropomorphic phantom which was extended by a solid water slab phantom. Dosimetric measurements were performed with TLD-700 rods, radiochromic films and a Farmer type ionisation chamber. The detectors were placed within the slab phantom and positioned along the isocentric longitudinal axis.
RESULTS: Using unflattened beams results in a reduction of treatment head leakage by 52% for 6 and 65% for 10 MV. Thus, peripheral doses were in general smaller for treatment plans calculated with unflattened beams. At about 20 cm distance from the field edge the dose was on average reduced by 23 and 31% for the 6 and 10 MV SBRT plans. For the IMRT plans (10 MV) the average reduction was 16% for the prostate and 18% for the head&neck case, respectively. For all examined cases, the relative deviation between peripheral doses of flattened and unflattened beams was found to increase with increasing distance from the field.
CONCLUSIONS: Removing the flattening filter lead to reduced peripheral doses for advanced treatment techniques. The relative difference between peripheral doses of flattened and unflattened beams was more pronounced when the nominal beam energy was increased. Patients may benefit by decreased exposure of normal tissue to scattered dose outside the field.
Copyright © 2010. Published by Elsevier GmbH.

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Year:  2010        PMID: 20888199     DOI: 10.1016/j.zemedi.2010.07.003

Source DB:  PubMed          Journal:  Z Med Phys        ISSN: 0939-3889            Impact factor:   4.820


  49 in total

1.  Comparison of surface dose delivered by 7 MV-unflattened and 6 MV-flattened photon beams.

Authors:  Ashokkumar Sigamani; Arunai Nambiraj
Journal:  Rep Pract Oncol Radiother       Date:  2017-04-25

2.  Measurement and comparison of head scatter factor for 7 MV unflattened (FFF) and 6 MV flattened photon beam using indigenously designed columnar mini phantom.

Authors:  Sigamani Ashokkumar; Arunai Nambiraj; Sujit Nath Sinha; Girigesh Yadav; Kothanda Raman; Manindra Bhushan; Rajesh Thiyagarajan
Journal:  Rep Pract Oncol Radiother       Date:  2015-03-01

3.  Impact of flattening-filter-free radiation on the clonogenic survival of astrocytic cell lines.

Authors:  Caroline Steenken; Jens Fleckenstein; Stefan Kegel; Lennart Jahnke; Anna Simeonova; Linda Hartmann; Jens Kübler; Marlon R Veldwijk; Frederik Wenz; Carsten Herskind; Frank Anton Giordano
Journal:  Strahlenther Onkol       Date:  2015-03-13       Impact factor: 3.621

4.  Dosimetric influence of filtered and flattening filter free photon beam on rapid arc (RA) radiotherapy planning in case of cervix carcinoma.

Authors:  Lalit Kumar; Girigesh Yadav; Kothanda Raman Samuvel; Manindra Bhushan; Pawan Kumar; Mahammood Suhail; Manoj Pal
Journal:  Rep Pract Oncol Radiother       Date:  2016-10-17

5.  Can treatment of pediatric Hodgkin's lymphoma be improved by PET imaging and proton therapy?

Authors:  B Knäusl; C Lütgendorf-Caucig; J Hopfgartner; K Dieckmann; L Kurch; T Pelz; R Pötter; D Georg
Journal:  Strahlenther Onkol       Date:  2012-11-18       Impact factor: 3.621

6.  Technical Report: Evaluation of peripheral dose for flattening filter free photon beams.

Authors:  E L Covington; T A Ritter; J M Moran; A M Owrangi; J I Prisciandaro
Journal:  Med Phys       Date:  2016-08       Impact factor: 4.071

7.  A surface energy spectral study on the bone heterogeneity and beam obliquity using the flattened and unflattened photon beams.

Authors:  James C L Chow; Amir M Owrangi
Journal:  Rep Pract Oncol Radiother       Date:  2015-11-30

8.  Dosimetric comparison of intracranial metastasis treatment using two radiosurgery systems: TrueBeam STx with VMAT and Gamma Knife Model 4C.

Authors:  Vance Keeling; Ozer Algan; Salahuddin Ahmad; Sabbir Hossain
Journal:  J Radiosurg SBRT       Date:  2016

9.  Improved clinical efficiency in CNS stereotactic radiosurgery using a flattening filter free linear accelerator.

Authors:  Brendan M Prendergast; Richard A Popple; Grant M Clark; Sharon A Spencer; Bart Guthrie; James Markert; John B Fiveash
Journal:  J Radiosurg SBRT       Date:  2011

10.  Second Cancer Risk after simultaneous integrated boost radiation therapy of right sided breast cancer with and without flattening filter.

Authors:  Barbara Dobler; Johannes Maier; Bernadette Knott; Manuel Maerz; Rainer Loeschel; Oliver Koelbl
Journal:  Strahlenther Onkol       Date:  2016-08-17       Impact factor: 3.621

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