Literature DB >> 20831164

Chemoselective attachment of small molecule effector functionality to human adenoviruses facilitates gene delivery to cancer cells.

Partha Sarathi Banerjee1, Philomena Ostapchuk, Patrick Hearing, Isaac Carrico.   

Abstract

We demonstrate here a novel two-step "click" labeling process in which adenoviral particles are first metabolically labeled during production with unnatural azido sugars. Subsequent chemoselective modification allows access to viruses decorated with a broad array of effector functionality. Adenoviruses modified with folate, a known cancer-targeting motif, demonstrated a marked increase in gene delivery to a murine cancer cell line.

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Year:  2010        PMID： 20831164      PMCID： PMC4086407          DOI： 10.1021/ja104547x

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  30 in total

Review 1.  Adenoviral vectors for gene transfer and therapy.

Authors:  Christoph Volpers; Stefan Kochanek
Journal:  J Gene Med       Date:  2004-02       Impact factor: 4.565

2.  Virus-glycopolymer conjugates by copper(I) catalysis of atom transfer radical polymerization and azide-alkyne cycloaddition.

Authors:  Sayam Sen Gupta; Krishnaswami S Raja; Eiton Kaltgrad; Erica Strable; M G Finn
Journal:  Chem Commun (Camb)       Date:  2005-07-19       Impact factor: 6.222

3.  Combined genetic and chemical capsid modifications enable flexible and efficient de- and retargeting of adenovirus vectors.

Authors:  Florian Kreppel; Judith Gackowski; Erika Schmidt; Stefan Kochanek
Journal:  Mol Ther       Date:  2005-07       Impact factor: 11.454

4.  Replication properties of human adenovirus in vivo and in cultures of primary cells from different animal species.

Authors:  Christian Jogler; Dennis Hoffmann; Dirk Theegarten; Thomas Grunwald; Klaus Uberla; Oliver Wildner
Journal:  J Virol       Date:  2006-04       Impact factor: 5.103

Review 5.  Current issues and future directions of oncolytic adenoviruses.

Authors:  Masato Yamamoto; David T Curiel
Journal:  Mol Ther       Date:  2009-11-24       Impact factor: 11.454

6.  Identification of the glycosylation site of the adenovirus type 5 fiber protein.

Authors:  Gilles Cauet; Jean-Marc Strub; Emmanuelle Leize; Elsa Wagner; Alain Van Dorsselaer; Monika Lusky
Journal:  Biochemistry       Date:  2005-04-12       Impact factor: 3.162

7.  Accelerated bioorthogonal conjugation: a practical method for the ligation of diverse functional molecules to a polyvalent virus scaffold.

Authors:  Sayam Sen Gupta; Jane Kuzelka; Pratik Singh; Warren G Lewis; Marianne Manchester; M G Finn
Journal:  Bioconjug Chem       Date:  2005 Nov-Dec       Impact factor: 4.774

8.  Relative accessibility of N-acetylglucosamine in trimers of the adenovirus types 2 and 5 fiber proteins.

Authors:  K G Mullis; R S Haltiwanger; G W Hart; R B Marchase; J A Engler
Journal:  J Virol       Date:  1990-11       Impact factor: 5.103

9.  Folate immobilized and PEGylated adenovirus for retargeting to tumor cells.

Authors:  In Kyung Oh; Hyejung Mok; Tae Gwan Park
Journal:  Bioconjug Chem       Date:  2006 May-Jun       Impact factor: 4.774

Review 10.  Targeted and shielded adenovectors for cancer therapy.

Authors:  Susan J Hedley; Jian Chen; John D Mountz; Jing Li; David T Curiel; Nikolay Korokhov; Imre Kovesdi
Journal:  Cancer Immunol Immunother       Date:  2006-04-13       Impact factor: 6.968
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  16 in total

Review 1.  Click chemistry in complex mixtures: bioorthogonal bioconjugation.

Authors:  Craig S McKay; M G Finn
Journal:  Chem Biol       Date:  2014-09-18

2.  Unnatural amino acid incorporation onto adenoviral (Ad) coat proteins facilitates chemoselective modification and retargeting of Ad type 5 vectors.

Authors:  Partha Sarathi Banerjee; Philomena Ostapchuk; Patrick Hearing; Isaac Sheridan Carrico
Journal:  J Virol       Date:  2011-05-25       Impact factor: 5.103

Review 3.  Physical, chemical, and synthetic virology: Reprogramming viruses as controllable nanodevices.

Authors:  Maria Yanqing Chen; Susan S Butler; Weitong Chen; Junghae Suh
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2018-11-08

4.  Targeted and armed oncolytic adenovirus via chemoselective modification.

Authors:  Partha S Banerjee; Edison S Zuniga; Iwao Ojima; Isaac S Carrico
Journal:  Bioorg Med Chem Lett       Date:  2011-05-20       Impact factor: 2.823

Review 5.  Click chemistry for drug delivery nanosystems.

Authors:  Enrique Lallana; Ana Sousa-Herves; Francisco Fernandez-Trillo; Ricardo Riguera; Eduardo Fernandez-Megia
Journal:  Pharm Res       Date:  2011-09-13       Impact factor: 4.200

6.  N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation.

Authors:  Leslie A Bateman; Balyn W Zaro; Kelly N Chuh; Matthew R Pratt
Journal:  Chem Commun (Camb)       Date:  2012-12-12       Impact factor: 6.222

7.  Chemical reporters for fluorescent detection and identification of O-GlcNAc-modified proteins reveal glycosylation of the ubiquitin ligase NEDD4-1.

Authors:  Balyn W Zaro; Yu-Ying Yang; Howard C Hang; Matthew R Pratt
Journal:  Proc Natl Acad Sci U S A       Date:  2011-05-03       Impact factor: 11.205

8.  Copper-Catalyzed Azide-Alkyne Click Chemistry for Bioconjugation.

Authors:  Stanislav I Presolski; Vu Phong Hong; M G Finn
Journal:  Curr Protoc Chem Biol       Date:  2011-12-01

9.  Chemoselective modification of viral surfaces via bioorthogonal click chemistry.

Authors:  Frederick A Rubino; Yoon Hyeun Oum; Lakshmi Rajaram; Yanjie Chu; Isaac S Carrico
Journal:  J Vis Exp       Date:  2012-08-19       Impact factor: 1.355

10.  Click labeling of unnatural sugars metabolically incorporated into viral envelope glycoproteins enables visualization of single particle fusion.

Authors:  Yoon Hyeun Oum; Tanay M Desai; Mariana Marin; Gregory B Melikyan
Journal:  J Virol Methods       Date:  2016-03-29       Impact factor: 2.014
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