Literature DB >> 20821097

A parameter study of pencil beam proton dose distributions for the treatment of ocular melanoma utilizing spot scanning.

Kenneth Sutherland1, Satoshi Miyajima, Hiroyuki Date, Hiroki Shirato, Masayori Ishikawa, Masao Murakami, Mitsuru Yamagiwa, Paul Bolton, Toshiki Tajima.   

Abstract

The results of Monte Carlo calculated dose distributions of proton treatment of ocular melanoma are presented. An efficient spot scanning method utilizing active energy modulation, which also minimizes the number of target spots was developed. We simulated various parameter values for the particle energy spread and the pencil beam diameter in order to determine values suitable for medical treatment. We found that a 2.5-mm-diameter proton beam with a 5% Gaussian energy spread was suitable for treatment of ocular melanoma while preserving vision for the typical case that we simulated. The energy spectra and the required proton current were also calculated and are reported. The results are intended to serve as a guideline for a new class of low-cost, compact accelerators.

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Year:  2009        PMID: 20821097     DOI: 10.1007/s12194-009-0071-4

Source DB:  PubMed          Journal:  Radiol Phys Technol        ISSN: 1865-0333


  10 in total

1.  Correlation between CT numbers and tissue parameters needed for Monte Carlo simulations of clinical dose distributions.

Authors:  W Schneider; T Bortfeld; W Schlegel
Journal:  Phys Med Biol       Date:  2000-02       Impact factor: 3.609

2.  Intensity modulated proton therapy: a clinical example.

Authors:  A J Lomax; T Boehringer; A Coray; E Egger; G Goitein; M Grossmann; P Juelke; S Lin; E Pedroni; B Rohrer; W Roser; B Rossi; B Siegenthaler; O Stadelmann; H Stauble; C Vetter; L Wisser
Journal:  Med Phys       Date:  2001-03       Impact factor: 4.071

3.  Validation of GEANT4, an object-oriented Monte Carlo toolkit, for simulations in medical physics.

Authors:  J F Carrier; L Archambault; L Beaulieu; R Roy
Journal:  Med Phys       Date:  2004-03       Impact factor: 4.071

4.  Adaptation of GEANT4 to Monte Carlo dose calculations based on CT data.

Authors:  H Jiang; H Paganetti
Journal:  Med Phys       Date:  2004-10       Impact factor: 4.071

5.  Treatment planning and verification of proton therapy using spot scanning: initial experiences.

Authors:  Antony J Lomax; Terence Böhringer; Alessandra Bolsi; Doelf Coray; Frank Emert; Gudrun Goitein; Martin Jermann; Shixiong Lin; Eros Pedroni; Hanspeter Rutz; Otto Stadelmann; Beate Timmermann; Jorn Verwey; Damien C Weber
Journal:  Med Phys       Date:  2004-11       Impact factor: 4.071

6.  Within the next decade conventional cyclotrons for proton radiotherapy will become obsolete and replaced by far less expensive machines using compact laser systems for the acceleration of the protons.

Authors:  Chang-Ming Charlie Ma; Richard L Maughan
Journal:  Med Phys       Date:  2006-03       Impact factor: 4.071

7.  Proton beam radiotherapy for uveal melanoma: results of Curie Institut-Orsay proton therapy center (ICPO).

Authors:  Rémi Dendale; Livia Lumbroso-Le Rouic; Georges Noel; Loïc Feuvret; Christine Levy; Sabine Delacroix; Anne Meyer; Catherine Nauraye; Alejandro Mazal; Hamid Mammar; Paul Garcia; François D'Hermies; Eric Frau; Corine Plancher; Bernard Asselain; Pierre Schlienger; Jean Jacques Mazeron; Laurence Desjardins
Journal:  Int J Radiat Oncol Biol Phys       Date:  2006-05-02       Impact factor: 7.038

8.  Spot scanning system for proton radiotherapy.

Authors:  T Kanai; K Kawachi; Y Kumamoto; H Ogawa; T Yamada; H Matsuzawa; T Inada
Journal:  Med Phys       Date:  1980 Jul-Aug       Impact factor: 4.071

9.  Practicability of protontherapy using compact laser systems.

Authors:  Victor Malka; Sven Fritzler; Erik Lefebvre; Emmanuel d'Humières; Régis Ferrand; Georges Grillon; Claude Albaret; Samuel Meyroneinc; Jean-Paul Chambaret; Andre Antonetti; Danièle Hulin
Journal:  Med Phys       Date:  2004-06       Impact factor: 4.071

Review 10.  Secondary neutrons in clinical proton radiotherapy: a charged issue.

Authors:  David J Brenner; Eric J Hall
Journal:  Radiother Oncol       Date:  2008-01-14       Impact factor: 6.280

  10 in total

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