Literature DB >> 20806307

Multifaceted modes of action for the glutarimide-containing polyketides revealed.

Scott R Rajski1, Ben Shen.   

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Year:  2010        PMID: 20806307      PMCID: PMC3517116          DOI: 10.1002/cbic.201000370

Source DB:  PubMed          Journal:  Chembiochem        ISSN: 1439-4227            Impact factor:   3.164


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  27 in total

1.  Migrastatin, a new inhibitor of tumor cell migration from Streptomyces sp. MK929-43F1. Taxonomy, fermentation, isolation and biological activities.

Authors:  K Nakae; Y Yoshimoto; T Sawa; Y Homma; M Hamada; T Takeuchi; M Imoto
Journal:  J Antibiot (Tokyo)       Date:  2000-10       Impact factor: 2.649

2.  Oxidative modification of NK30424A and B enhance inhibitory effect on lipopolysaccharide-induced tumour necrosis factor-alpha promoter activity.

Authors:  Yoshiyuki Takayasu; Kouichi Tsuchiya; Yoshikazu Sukenaga
Journal:  J Antibiot (Tokyo)       Date:  2002-03       Impact factor: 2.649

3.  Absolute configuration of migrastatin, a novel 14-membered ring macrolide.

Authors:  Hikaru Nakamura; Yoshikazu Takahashi; Hiroshi Naganawa; Koichi Nakae; Masaya Imoto; Motoo Shiro; Koji Matsumura; Hidenori Watanabe; Takeshi Kitahara
Journal:  J Antibiot (Tokyo)       Date:  2002-04       Impact factor: 2.649

4.  Iso-migrastatin congeners from Streptomyces platensis and generation of a glutarimide polyketide library featuring the dorrigocin, lactimidomycin, migrastatin, and NK30424 scaffolds.

Authors:  Jianhua Ju; Si-Kyu Lim; Hui Jiang; Jeong-Woo Seo; Ben Shen
Journal:  J Am Chem Soc       Date:  2005-08-31       Impact factor: 15.419

5.  Confirmation of the Structures of Synthetic Derivatives of Migrastatin in the Light of Recently Disclosed Crystallographically Based Claims.

Authors:  Pavel Nagorny; Isaac Krauss; Jón T Njardarson; Lucy Perez; Christoph Gaul; Guangli Yang; Ouathek Ouerfelli; Samuel J Danishefsky
Journal:  Tetrahedron Lett       Date:  2010-07-28       Impact factor: 2.415

Review 6.  Cell migration in tumors.

Authors:  Hideki Yamaguchi; Jeffrey Wyckoff; John Condeelis
Journal:  Curr Opin Cell Biol       Date:  2005-10       Impact factor: 8.382

7.  Migrastatin and a new compound, isomigrastatin, from Streptomyces platensis.

Authors:  Elaine J Woo; Courtney M Starks; John R Carney; Robert Arslanian; Lawrence Cadapan; Stefan Zavala; Peter Licari
Journal:  J Antibiot (Tokyo)       Date:  2002-02       Impact factor: 2.649

8.  New lactimidomycin congeners shed insight into lactimidomycin biosynthesis in Streptomyces amphibiosporus.

Authors:  Jianhua Ju; Jeong-Woo Seo; Yeng Her; Si-Kyu Lim; Ben Shen
Journal:  Org Lett       Date:  2007-11-13       Impact factor: 6.005

9.  Dorrigocins: novel antifungal antibiotics that change the morphology of ras-transformed NIH/3T3 cells to that of normal cells. II. Isolation and elucidation of structures.

Authors:  J E Hochlowski; D N Whittern; P Hill; J B McAlpine
Journal:  J Antibiot (Tokyo)       Date:  1994-08       Impact factor: 2.649

10.  Lactimidomycin, iso-migrastatin and related glutarimide-containing 12-membered macrolides are extremely potent inhibitors of cell migration.

Authors:  Jianhua Ju; Scott R Rajski; Si-Kyu Lim; Jeong-Woo Seo; Noël R Peters; F Michael Hoffmann; Ben Shen
Journal:  J Am Chem Soc       Date:  2009-02-04       Impact factor: 15.419

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  8 in total

1.  Polyketide synthase chimeras reveal key role of ketosynthase domain in chain branching.

Authors:  Srividhya Sundaram; Daniel Heine; Christian Hertweck
Journal:  Nat Chem Biol       Date:  2015-10-19       Impact factor: 15.040

2.  A Long-Range Acting Dehydratase Domain as the Missing Link for C17-Dehydration in Iso-Migrastatin Biosynthesis.

Authors:  Bo Zhang; Zhengren Xu; Qihui Teng; Guohui Pan; Ming Ma; Ben Shen
Journal:  Angew Chem Int Ed Engl       Date:  2017-05-19       Impact factor: 15.336

3.  Vinylogous chain branching catalysed by a dedicated polyketide synthase module.

Authors:  Tom Bretschneider; Joel B Heim; Daniel Heine; Robert Winkler; Benjamin Busch; Björn Kusebauch; Thilo Stehle; Georg Zocher; Christian Hertweck
Journal:  Nature       Date:  2013-09-18       Impact factor: 49.962

4.  Post-polyketide synthase steps in iso-migrastatin biosynthesis, featuring tailoring enzymes with broad substrate specificity.

Authors:  Ming Ma; Thomas Kwong; Si-Kyu Lim; Jianhua Ju; Jeremy R Lohman; Ben Shen
Journal:  J Am Chem Soc       Date:  2013-02-11       Impact factor: 15.419

5.  Overproduction of lactimidomycin by cross-overexpression of genes encoding Streptomyces antibiotic regulatory proteins.

Authors:  Bo Zhang; Dong Yang; Yijun Yan; Guohui Pan; Wensheng Xiang; Ben Shen
Journal:  Appl Microbiol Biotechnol       Date:  2015-11-10       Impact factor: 4.813

6.  Sesbanimide R, a Novel Cytotoxic Polyketide Produced by Magnetotactic Bacteria.

Authors:  Ram Prasad Awal; Patrick A Haack; Chantal D Bader; Cornelius N Riese; Dirk Schüler; Rolf Müller
Journal:  mBio       Date:  2021-05-18       Impact factor: 7.867

7.  Comparative characterization of the lactimidomycin and iso-migrastatin biosynthetic machineries revealing unusual features for acyltransferase-less type I polyketide synthases and providing an opportunity to engineer new analogues.

Authors:  Jeong-Woo Seo; Ming Ma; Thomas Kwong; Jianhua Ju; Si-Kyu Lim; Hui Jiang; Jeremy R Lohman; Chunying Yang; John Cleveland; Emmanuel Zazopoulos; Chris M Farnet; Ben Shen
Journal:  Biochemistry       Date:  2014-12-01       Impact factor: 3.162

8.  Cycloheximide and actiphenol production in Streptomyces sp. YIM56141 governed by single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.

Authors:  Min Yin; Yijun Yan; Jeremy R Lohman; Sheng-Xiong Huang; Ming Ma; Guang-Rong Zhao; Li-Hua Xu; Wensheng Xiang; Ben Shen
Journal:  Org Lett       Date:  2014-05-09       Impact factor: 6.005

  8 in total

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