Literature DB >> 12061554

Absolute configuration of migrastatin, a novel 14-membered ring macrolide.

Hikaru Nakamura, Yoshikazu Takahashi, Hiroshi Naganawa, Koichi Nakae, Masaya Imoto, Motoo Shiro, Koji Matsumura, Hidenori Watanabe, Takeshi Kitahara.   

Abstract

Mesh：

Substances：

Year:  2002        PMID： 12061554     DOI： 10.7164/antibiotics.55.442

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


× No keyword cloud information.
  11 in total

1.  Thermolysis of isomigrastatin and its congeners via [3,3]-sigmatropic rearrangement: a new route to the synthesis of migrastatin and its analogues.

Authors:  Jianhua Ju; Si-Kyu Lim; Hui Jiang; Jeong-Woo Seo; Yeng Her; Ben Shen
Journal:  Org Lett       Date:  2006-12-07       Impact factor: 6.005

2.  Confirmation of the Structures of Synthetic Derivatives of Migrastatin in the Light of Recently Disclosed Crystallographically Based Claims.

Authors:  Pavel Nagorny; Isaac Krauss; Jón T Njardarson; Lucy Perez; Christoph Gaul; Guangli Yang; Ouathek Ouerfelli; Samuel J Danishefsky
Journal:  Tetrahedron Lett       Date:  2010-07-28       Impact factor: 2.415

Review 3.  Nitroso Diels-Alder (NDA) reaction as an efficient tool for the functionalization of diene-containing natural products.

Authors:  Serena Carosso; Marvin J Miller
Journal:  Org Biomol Chem       Date:  2014-10-14       Impact factor: 3.876

4.  Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin.

Authors:  Nicolas Lecomte; Jon T Njardarson; Pavel Nagorny; Guangli Yang; Robert Downey; Ouathek Ouerfelli; Malcolm A S Moore; Samuel J Danishefsky
Journal:  Proc Natl Acad Sci U S A       Date:  2011-08-01       Impact factor: 11.205

5.  Diverted total synthesis leads to the generation of promising cell-migration inhibitors for treatment of tumor metastasis: in vivo and mechanistic studies on the migrastatin core ether analog.

Authors:  Thordur Oskarsson; Pavel Nagorny; Isaac J Krauss; Lucy Perez; Mihirbaran Mandal; Guangli Yang; Ouathek Ouerfelli; Danhua Xiao; Malcolm A S Moore; Joan Massagué; Samuel J Danishefsky
Journal:  J Am Chem Soc       Date:  2010-03-10       Impact factor: 15.419

6.  Multifaceted modes of action for the glutarimide-containing polyketides revealed.

Authors:  Scott R Rajski; Ben Shen
Journal:  Chembiochem       Date:  2010-09-24       Impact factor: 3.164

7.  Evaluation of new migrastatin and dorrigocin congeners unveils cell migration inhibitors with dramatically improved potency.

Authors:  Jianhua Ju; Scott R Rajski; Si-Kyu Lim; Jeong-Woo Seo; Noël R Peters; F Michael Hoffmann; Ben Shen
Journal:  Bioorg Med Chem Lett       Date:  2008-07-24       Impact factor: 2.823

8.  Post-polyketide synthase steps in iso-migrastatin biosynthesis, featuring tailoring enzymes with broad substrate specificity.

Authors:  Ming Ma; Thomas Kwong; Si-Kyu Lim; Jianhua Ju; Jeremy R Lohman; Ben Shen
Journal:  J Am Chem Soc       Date:  2013-02-11       Impact factor: 15.419

9.  Migrastatin analogues inhibit canine mammary cancer cell migration and invasion.

Authors:  Kinga Majchrzak; Daniele Lo Re; Małgorzata Gajewska; Małgorzata Bulkowska; Agata Homa; Karol Pawłowski; Tomasz Motyl; Paul V Murphy; Magdalena Król
Journal:  PLoS One       Date:  2013-10-08       Impact factor: 3.240

10.  Comparative characterization of the lactimidomycin and iso-migrastatin biosynthetic machineries revealing unusual features for acyltransferase-less type I polyketide synthases and providing an opportunity to engineer new analogues.

Authors:  Jeong-Woo Seo; Ming Ma; Thomas Kwong; Jianhua Ju; Si-Kyu Lim; Hui Jiang; Jeremy R Lohman; Chunying Yang; John Cleveland; Emmanuel Zazopoulos; Chris M Farnet; Ben Shen
Journal:  Biochemistry       Date:  2014-12-01       Impact factor: 3.162
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.