Literature DB >> 20797954

Conditions and consequences of a BRCA mutation in young, single women of childbearing age.

Rebekah Hamilton1, Karen E Hurley.   

Abstract

PURPOSE/
OBJECTIVES: To explore the experiences of young, single women who are at increased risk for hereditary breast and ovarian cancer (HBOC) because of a BRCA mutation. RESEARCH APPROACH: Qualitative.
SETTING: Seven states and Canada. PARTICIPANTS: 11 single women aged 18-35 years who tested positive for a BRCA mutation. METHODOLOGIC APPROACH: Grounded theory with in-depth individual interviews conducted via e-mail or telephone.
FINDINGS: Analysis resulted in three conditions and three consequences. Conditions were dating or not dating, time in a relationship, and physical impact of surgery or breast cancer treatment. Consequences were explaining their choices, experiencing a sense of urgency, and experiencing a sense of loss.
CONCLUSIONS: Young women who are at risk for HBOC face a complex array of decisions after finding out that they carry a BRCA mutation. Being single and childless adds to this complexity.
INTERPRETATION: Nurses can listen to young women with HBOC risk, help them clarify their fears and understanding of their risk, and provide nonthreatening support that goes beyond simply providing more information and includes a nonjudgmental understanding of the young women's experience.

Entities:  

Mesh:

Year:  2010        PMID: 20797954     DOI: 10.1188/10.ONF.627-634

Source DB:  PubMed          Journal:  Oncol Nurs Forum        ISSN: 0190-535X            Impact factor:   2.172


  15 in total

Review 1.  Specific psychosocial issues of individuals undergoing genetic counseling for cancer - a literature review.

Authors:  Willem Eijzenga; Daniela E E Hahn; Neil K Aaronson; Irma Kluijt; Eveline M A Bleiker
Journal:  J Genet Couns       Date:  2013-08-31       Impact factor: 2.537

2.  Uptake of Preimplantation Genetic Diagnosis in Female BRCA1 and BRCA2 Mutation Carriers.

Authors:  Pnina Mor; Sarah Brennenstuhl; Kelly A Metcalfe
Journal:  J Genet Couns       Date:  2018-06-01       Impact factor: 2.537

Review 3.  Family Communication, Risk Perception and Cancer Knowledge of Young Adults from BRCA1/2 Families: a Systematic Review.

Authors:  Alison L Young; Phyllis N Butow; Janine Vetsch; Veronica F Quinn; Andrea F Patenaude; Katherine M Tucker; Claire E Wakefield
Journal:  J Genet Couns       Date:  2017-06-30       Impact factor: 2.537

4.  Reproductive Decision-Making in Women with BRCA1/2 Mutations.

Authors:  Jessica L Chan; Lauren N C Johnson; Mary D Sammel; Laura DiGiovanni; Chan Voong; Susan M Domchek; Clarisa R Gracia
Journal:  J Genet Couns       Date:  2016-10-28       Impact factor: 2.537

5.  Living my family's story: identifying the lived experience in healthy women at risk for hereditary breast cancer.

Authors:  Meghan L Underhill; Robin M Lally; Marc T Kiviniemi; Christine Murekeyisoni; Suzanne S Dickerson
Journal:  Cancer Nurs       Date:  2012 Nov-Dec       Impact factor: 2.592

6.  Experiences of Women Who Underwent Predictive BRCA 1/2 Mutation Testing Before the Age of 30.

Authors:  Kate Brunstrom; Alexandra Murray; Marion McAllister
Journal:  J Genet Couns       Date:  2015-05-19       Impact factor: 2.537

7.  Exploration of Male Attitudes on Partnerships and Sexuality with Female BRCA1/2 Mutation Carriers.

Authors:  Caitlin Mauer; Sara Spencer; Jeffery Dungan; Karen Hurley
Journal:  J Genet Couns       Date:  2015-08-08       Impact factor: 2.537

8.  Living With Genetic Vulnerability: a Life Course Perspective.

Authors:  Rebekah J Hamilton; Nancy A Innella; Dawn T Bounds
Journal:  J Genet Couns       Date:  2015-09-02       Impact factor: 2.537

9.  Unmet support needs and distress among women with a BRCA1/2 mutation.

Authors:  Ashley Farrelly; Victoria White; Bettina Meiser; Michael Jefford; Mary-Anne Young; Sandra Ieropoli; Ingrid Winship; Jessica Duffy
Journal:  Fam Cancer       Date:  2013-09       Impact factor: 2.375

10.  Seeking balance: decision support needs of women without cancer and a deleterious BRCA1 or BRCA2 mutation.

Authors:  Meghan L Underhill; Cheryl B Crotser
Journal:  J Genet Couns       Date:  2013-11-22       Impact factor: 2.537

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