Literature DB >> 2078033

Development of pentamidine analogues as new agents for the treatment of Pneumocystis carinii pneumonia.

R R Tidwell1, S K Jones, J D Geratz, K A Ohemeng, C A Bell, B J Berger, J E Hall.   

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Year:  1990        PMID： 2078033     DOI： 10.1111/j.1749-6632.1990.tb17862.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


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  15 in total

1.  CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime].

Authors:  Michael Zhuo Wang; Janelle Y Saulter; Etsuko Usuki; Yen-Ling Cheung; Michael Hall; Arlene S Bridges; Greg Loewen; Oliver T Parkinson; Chad E Stephens; James L Allen; Darryl C Zeldin; David W Boykin; Richard R Tidwell; Andrew Parkinson; Mary F Paine; James Edwin Hall
Journal:  Drug Metab Dispos       Date:  2006-09-22       Impact factor: 3.922

2.  Activity of pentamidine and pentamidine analogs against Toxoplasma gondii in cell cultures.

Authors:  D S Lindsay; B L Blagburn; J E Hall; R R Tidwell
Journal:  Antimicrob Agents Chemother       Date:  1991-09       Impact factor: 5.191

3.  In vitro selection and in vivo efficacy of piperazine- and alkanediamide-linked bisbenzamidines against Pneumocystis pneumonia in mice.

Authors:  Melanie T Cushion; Peter D Walzer; Alan Ashbaugh; Sandra Rebholz; Ronald Brubaker; Jean Jacques Vanden Eynde; Annie Mayence; Tien L Huang
Journal:  Antimicrob Agents Chemother       Date:  2006-07       Impact factor: 5.191

4.  Immunoassays for pentamidine and related compounds: development of a facile inhibitory ELISA suitable for clinical use.

Authors:  H M Reisner; D R Gray; S K Jones; B G Rose; R R Tidwell
Journal:  J Clin Lab Anal       Date:  2000       Impact factor: 2.352

5.  Analogs of pentamidine as potential anti-Pneumocystis chemotherapeutics.

Authors:  Dorota Maciejewska; Jerzy Zabinski; Pawel Kaźmierczak; Mateusz Rezler; Barbara Krassowska-Świebocka; Margaret S Collins; Melanie T Cushion
Journal:  Eur J Med Chem       Date:  2011-12-13       Impact factor: 6.514

6.  Activity of cationically substituted bis-benzimidazoles against experimental Pneumocystis carinii pneumonia.

Authors:  R R Tidwell; S K Jones; N A Naiman; L C Berger; W B Brake; C C Dykstra; J E Hall
Journal:  Antimicrob Agents Chemother       Date:  1993-08       Impact factor: 5.191

Review 7.  Pharmacokinetic optimisation in the treatment of Pneumocystis carinii pneumonia.

Authors:  H F Vöhringer; K Arastéh
Journal:  Clin Pharmacokinet       Date:  1993-05       Impact factor: 6.447

8.  Comparative efficacy evaluation of dicationic carbazole compounds, nitazoxanide, and paromomycin against Cryptosporidium parvum infections in a neonatal mouse model.

Authors:  B L Blagburn; K L Drain; T M Land; R G Kinard; P H Moore; D S Lindsay; D A Patrick; D W Boykin; R R Tidwell
Journal:  Antimicrob Agents Chemother       Date:  1998-11       Impact factor: 5.191

9.  Structure, expression and phylogenetic analysis of the gene encoding actin I in Pneumocystis carinii.

Authors:  L D Fletcher; J M McDowell; R R Tidwell; R B Meagher; C C Dykstra
Journal:  Genetics       Date:  1994-07       Impact factor: 4.562

10.  Interactions of DB75, a novel antimalarial agent, with other antimalarial drugs in vitro.

Authors:  Anne E Purfield; Richard R Tidwell; Steven R Meshnick
Journal:  Antimicrob Agents Chemother       Date:  2008-03-24       Impact factor: 5.191
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