Literature DB >> 20731875

Diagnostic and treatment pathways for men with prostate cancer in Queensland: investigating spatial and demographic inequalities.

Peter D Baade1, Joanne F Aitken, Megan Ferguson, Robert A Gardiner, Suzanne K Chambers.   

Abstract

BACKGROUND: Patterns of diagnosis and management for men diagnosed with prostate cancer in Queensland, Australia, have not yet been systematically documented and so assumptions of equity are untested. This longitudinal study investigates the association between prostate cancer diagnostic and treatment outcomes and key area-level characteristics and individual-level demographic, clinical and psychosocial factors. METHODS/
DESIGN: A total of 1064 men diagnosed with prostate cancer between February 2005 and July 2007 were recruited through hospital-based urology outpatient clinics and private practices in the centres of Brisbane, Townsville and Mackay (82% of those referred). Additional clinical and diagnostic information for all 6609 men diagnosed with prostate cancer in Queensland during the study period was obtained via the population-based Queensland Cancer Registry.Respondent data are collected using telephone and self-administered questionnaires at pre-treatment and at 2 months, 6 months, 12 months, 24 months, 36 months, 48 months and 60 months post-treatment. Assessments include demographics, medical history, patterns of care, disease and treatment characteristics together with outcomes associated with prostate cancer, as well as information about quality of life and psychological adjustment. Complementary detailed treatment information is abstracted from participants' medical records held in hospitals and private treatment facilities and collated with health service utilisation data obtained from Medicare Australia. Information about the characteristics of geographical areas is being obtained from data custodians such as the Australian Bureau of Statistics. Geo-coding and spatial technology will be used to calculate road travel distances from patients' residences to treatment centres. Analyses will be conducted using standard statistical methods along with multilevel regression models including individual and area-level components.
CONCLUSIONS: Information about the diagnostic and treatment patterns of men diagnosed with prostate cancer is crucial for rational planning and development of health delivery and supportive care services to ensure equitable access to health services, regardless of geographical location and individual characteristics.This study is a secondary outcome of the randomised controlled trial registered with the Australian New Zealand Clinical Trials Registry (ACTRN12607000233426).

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Year:  2010        PMID: 20731875      PMCID: PMC2936907          DOI: 10.1186/1471-2407-10-452

Source DB:  PubMed          Journal:  BMC Cancer        ISSN: 1471-2407            Impact factor:   4.430


  25 in total

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6.  Urban-rural differences in prostate cancer mortality, radical prostatectomy and prostate-specific antigen testing in Australia.

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8.  Overdiagnosis due to prostate-specific antigen screening: lessons from U.S. prostate cancer incidence trends.

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1.  Association between single-nucleotide polymorphisms in growth factor genes and quality of life in men with prostate cancer and the general population.

Authors:  Kimberly E Alexander; Suzanne Chambers; Amanda B Spurdle; Jyotsna Batra; Felicity Lose; Tracy A O'Mara; Robert A Gardiner; Joanne F Aitken; Judith A Clements; Mary-Anne Kedda; Monika Janda
Journal:  Qual Life Res       Date:  2015-02-28       Impact factor: 4.147

2.  Genetic association of the KLK4 locus with risk of prostate cancer.

Authors:  Felicity Lose; Srilakshmi Srinivasan; Tracy O'Mara; Louise Marquart; Suzanne Chambers; Robert A Gardiner; Joanne F Aitken; Amanda B Spurdle; Jyotsna Batra; Judith A Clements
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3.  Association between Prostinogen (KLK15) genetic variants and prostate cancer risk and aggressiveness in Australia and a meta-analysis of GWAS data.

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  5 in total

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