Literature DB >> 20690779

Fluorescent ribonucleoside as a FRET acceptor for tryptophan in native proteins.

Yun Xie1, Tucker Maxson, Yitzhak Tor.   

Abstract

A new fluorescent ribonucleoside analogue, containing 5-aminoquinazoline-2,4(1H,3H)-dione, acts as a Forster resonance energy transfer acceptor for tryptophan (R(0) = 22 A) and displays visible emission (440 nm). As tryptophan is frequently found at or near the recognition domains of RNA binding proteins, this FRET pair facilitates the study of RNA binding to native proteins and peptides, which is demonstrated here for the HIV-1 Rev association with the Rev Response Element (RRE).

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20690779      PMCID： PMC2941768          DOI： 10.1021/ja105244t

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  21 in total

1.  Peptide-triggered conformational switch in HIV-1 RRE RNA complexes.

Authors:  Y Gosser; T Hermann; A Majumdar; W Hu; R Frederick; F Jiang; W Xu; D J Patel
Journal:  Nat Struct Biol       Date:  2001-02

2.  A Novel Solid-Phase Assembly for Identifying Potent and Selective RNA Ligands We thank Professors David Wilson and David Boykin for a generous gift of the aromatic amidine derivatives and Professor Kol for a generous gift of eilatin-containing complexes. We are grateful to Dr. Georg Schlechtingen and Professor Murray Goodman for assistance with peptide synthesis and to Ibis Therapeutics for partial support. N.W.L. is supported by a National Institute of Health Molecular Biophysics Training Grant (GM 08326).

Authors: 
Journal:  Angew Chem Int Ed Engl       Date:  2000-05-15       Impact factor: 15.336

Review 3.  Regulation of expression of human immunodeficiency virus.

Authors:  G N Pavlakis; B K Felber
Journal:  New Biol       Date:  1990-01

Review 4.  Single-molecule fluorescence methods for the analysis of RNA folding and ribonucleoprotein assembly.

Authors:  Goran Pljevaljcić; David P Millar
Journal:  Methods Enzymol       Date:  2008       Impact factor: 1.600

Review 5.  The biochemistry of AIDS.

Authors:  Y N Vaishnav; F Wong-Staal
Journal:  Annu Rev Biochem       Date:  1991       Impact factor: 23.643

Review 6.  The HIV-1 Rev protein.

Authors:  V W Pollard; M H Malim
Journal:  Annu Rev Microbiol       Date:  1998       Impact factor: 15.500

Review 7.  Inhibition of the HIV Rev transactivator : a new target for therapeutic intervention.

Authors:  A Heguy
Journal:  Front Biosci       Date:  1997-06-01

Review 8.  Anisotropy decay of fluorescence as an experimental approach to protein dynamics.

Authors:  E Bucci; R F Steiner
Journal:  Biophys Chem       Date:  1988-07-15       Impact factor: 2.352

9.  Antibiotic selectivity for prokaryotic vs. eukaryotic decoding sites.

Authors:  Yun Xie; Andrew V Dix; Yitzhak Tor
Journal:  Chem Commun (Camb)       Date:  2010-05-13       Impact factor: 6.222

Review 10.  Fluorescence-based methods for evaluating the RNA affinity and specificity of HIV-1 Rev-RRE inhibitors.

Authors:  Nathan W Luedtke; Yitzhak Tor
Journal:  Biopolymers       Date:  2003-09       Impact factor: 2.505
View more
  12 in total

Review 1.  Novel modifications in RNA.

Authors:  Kelly Phelps; Alexi Morris; Peter A Beal
Journal:  ACS Chem Biol       Date:  2011-12-23       Impact factor: 5.100

2.  Design, synthesis, and spectroscopic properties of extended and fused pyrrolo-dC and pyrrolo-C analogs.

Authors:  Mary S Noé; Andro C Ríos; Yitzhak Tor
Journal:  Org Lett       Date:  2012-05-30       Impact factor: 6.005

3.  Modified 6-aza uridines: highly emissive pH-sensitive fluorescent nucleosides.

Authors:  Renatus W Sinkeldam; Patrycja A Hopkins; Yitzhak Tor
Journal:  Chemphyschem       Date:  2012-07-06       Impact factor: 3.102

4.  Comparison of Förster-resonance-energy-transfer acceptors for tryptophan and tyrosine residues in native proteins as donors.

Authors:  Yi zhang; Xiaolan Yang; Lin Liu; Xuexia Huang; Zuexia Huang; Jun Pu; Gaobo Long; Ling Zhang; Dong Liu; Bangtian Xu; Juan Liao; Fei Liao
Journal:  J Fluoresc       Date:  2012-09-22       Impact factor: 2.217

5.  Emissive RNA alphabet.

Authors:  Dongwon Shin; Renatus W Sinkeldam; Yitzhak Tor
Journal:  J Am Chem Soc       Date:  2011-09-02       Impact factor: 15.419

6.  Emissive Synthetic Cofactors: Enzymatic Interconversions of tz A Analogues of ATP, NAD+ , NADH, NADP+ , and NADPH.

Authors:  François Hallé; Andrea Fin; Alexander R Rovira; Yitzhak Tor
Journal:  Angew Chem Int Ed Engl       Date:  2017-12-21       Impact factor: 15.336

7.  The components of xRNA: synthesis and fluorescence of a full genetic set of size-expanded ribonucleosides.

Authors:  Armando R Hernández; Eric T Kool
Journal:  Org Lett       Date:  2011-01-07       Impact factor: 6.005

8.  Enzymatic interconversion of isomorphic fluorescent nucleosides: adenosine deaminase transforms an adenosine analogue into an inosine analogue.

Authors:  Renatus W Sinkeldam; Lisa S McCoy; Dongwon Shin; Yitzhak Tor
Journal:  Angew Chem Int Ed Engl       Date:  2013-11-29       Impact factor: 15.336

9.  Responsive fluorescent nucleotides serve as efficient substrates to probe terminal uridylyl transferase.

Authors:  Jerrin Thomas George; Seergazhi G Srivatsan
Journal:  Chem Commun (Camb)       Date:  2020-09-17       Impact factor: 6.222

10.  Structure-function relationship of substituted bromomethylcoumarins in nucleoside specificity of RNA alkylation.

Authors:  Stefanie Kellner; Laura Bettina Kollar; Antonia Ochel; Manjunath Ghate; Mark Helm
Journal:  PLoS One       Date:  2013-07-03       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.