Literature DB >> 22148740

Novel modifications in RNA.

Kelly Phelps1, Alexi Morris, Peter A Beal.   

Abstract

The past several years have seen numerous reports of new chemical modifications for use in RNA. In addition, in that time period, we have seen the discovery of several previously unknown naturally occurring modifications that impart novel properties on the parent RNAs. In this review, we describe recent discoveries in these areas with a focus on RNA modifications that introduce spectroscopic tags, reactive handles, or new recognition properties.

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Year:  2011        PMID： 22148740      PMCID： PMC3270579          DOI： 10.1021/cb200422t

Source DB:  PubMed          Journal:  ACS Chem Biol        ISSN： 1554-8929            Impact factor:   5.100


  93 in total

1.  A radically different mechanism for S-adenosylmethionine-dependent methyltransferases.

Authors:  Tyler L Grove; Jack S Benner; Matthew I Radle; Jessica H Ahlum; Bradley J Landgraf; Carsten Krebs; Squire J Booker
Journal:  Science       Date:  2011-03-17       Impact factor: 47.728

2.  Protein synthesis: Stop the nonsense.

Authors:  Adrian R Ferré-D'Amaré
Journal:  Nature       Date:  2011-06-15       Impact factor: 49.962

3.  Nucleobase and ribose modifications control immunostimulation by a microRNA-122-mimetic RNA.

Authors:  Hayden Peacock; Raymond V Fucini; Prasanna Jayalath; José M Ibarra-Soza; Henry J Haringsma; W Michael Flanagan; Aarron Willingham; Peter A Beal
Journal:  J Am Chem Soc       Date:  2011-06-01       Impact factor: 15.419

4.  Effect of north bicyclo[3.1.0]hexane 2'-deoxy-pseudosugars on RNA interference: a novel class of siRNA modification.

Authors:  Montserrat Terrazas; Sandra M Ocampo; José Carlos Perales; Victor E Marquez; Ramon Eritja
Journal:  Chembiochem       Date:  2011-03-30       Impact factor: 3.164

5.  8-Oxoguanosine switches modulate the activity of alkylated siRNAs by controlling steric effects in the major versus minor grooves.

Authors:  Arunkumar Kannan; Erik Fostvedt; Peter A Beal; Cynthia J Burrows
Journal:  J Am Chem Soc       Date:  2011-03-31       Impact factor: 15.419

6.  A direct, efficient method for the preparation of siRNAs containing ribo-like North bicyclo[3.1.0]hexane pseudosugars.

Authors:  Montserrat Terrazas; Anna Aviñó; Maqbool A Siddiqui; Victor E Marquez; Ramon Eritja
Journal:  Org Lett       Date:  2011-05-09       Impact factor: 6.005

7.  Structural basis for methyl transfer by a radical SAM enzyme.

Authors:  Amie K Boal; Tyler L Grove; Monica I McLaughlin; Neela H Yennawar; Squire J Booker; Amy C Rosenzweig
Journal:  Science       Date:  2011-04-28       Impact factor: 47.728

8.  Synthesis and properties of triazole-linked RNA.

Authors:  Daniel Mutisya; Chelliah Selvam; Scott D Kennedy; Eriks Rozners
Journal:  Bioorg Med Chem Lett       Date:  2011-04-05       Impact factor: 2.823

9.  Converting nonsense codons into sense codons by targeted pseudouridylation.

Authors:  John Karijolich; Yi-Tao Yu
Journal:  Nature       Date:  2011-06-15       Impact factor: 49.962

10.  Probing RNA dynamics via longitudinal exchange and CPMG relaxation dispersion NMR spectroscopy using a sensitive 13C-methyl label.

Authors:  Karin Kloiber; Romana Spitzer; Martin Tollinger; Robert Konrat; Christoph Kreutz
Journal:  Nucleic Acids Res       Date:  2011-01-19       Impact factor: 16.971
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  24 in total

1.  Tautomers of a Fluorescent G Surrogate and Their Distinct Photophysics Provide Additional Information Channels.

Authors:  Marianna Sholokh; Roberto Improta; Mattia Mori; Rajhans Sharma; Cyril Kenfack; Dongwon Shin; Karine Voltz; Roland H Stote; Olga A Zaporozhets; Maurizio Botta; Yitzhak Tor; Yves Mély
Journal:  Angew Chem Int Ed Engl       Date:  2016-06-08       Impact factor: 15.336

2.  Synthesis and evaluation of an alkyne-modified ATP analog for enzymatic incorporation into RNA.

Authors:  Yuxuan Zheng; Peter A Beal
Journal:  Bioorg Med Chem Lett       Date:  2016-02-18       Impact factor: 2.823

3.  Polymerase-Mediated Site-Specific Incorporation of a Synthetic Fluorescent Isomorphic G Surrogate into RNA.

Authors:  Yao Li; Andrea Fin; Lisa McCoy; Yitzhak Tor
Journal:  Angew Chem Int Ed Engl       Date:  2016-12-21       Impact factor: 15.336

4.  Synthesis, X-ray and Fluorescence Characteristics of Pyrimido[5,4-e]thiazolo[3,2-a]pyrimidine as a Novel Heterocyclic System.

Authors:  Zahra Ebrahimpour; Mehdi Bakavoli; Ali Shiri; Seyed Mohammad Seyedi; Tayebe Asghari; Joel T Mague
Journal:  J Fluoresc       Date:  2017-03-10       Impact factor: 2.217

Review 5.  The delivery of therapeutic oligonucleotides.

Authors:  Rudolph L Juliano
Journal:  Nucleic Acids Res       Date:  2016-04-15       Impact factor: 16.971

Review 6.  Cellular uptake and intracellular trafficking of oligonucleotides: implications for oligonucleotide pharmacology.

Authors:  R L Juliano; Xin Ming; Kyle Carver; Brian Laing
Journal:  Nucleic Acid Ther       Date:  2014-01-02       Impact factor: 5.486

7.  Synthesis of DNA and RNA Oligonucleotides Containing a Dual-Purpose Selenium-Modified Fluorescent Nucleoside Probe.

Authors:  Ashok Nuthanakanti; Seergazhi G Srivatsan
Journal:  Curr Protoc Nucleic Acid Chem       Date:  2020-06

8.  Covalent conjugation of oligonucleotides with cell-targeting ligands.

Authors:  Md Rowshon Alam; Xin Ming; Osamu Nakagawa; Jian Jin; R L Juliano
Journal:  Bioorg Med Chem       Date:  2013-06-01       Impact factor: 3.641

Review 9.  Computational approaches to predicting the impact of novel bases on RNA structure and stability.

Authors:  Jason G Harrison; Yvonne B Zheng; Peter A Beal; Dean J Tantillo
Journal:  ACS Chem Biol       Date:  2013-10-08       Impact factor: 5.100

Review 10.  Bioengineering of noncoding RNAs for research agents and therapeutics.

Authors:  Pui Yan Ho; Ai-Ming Yu
Journal:  Wiley Interdiscip Rev RNA       Date:  2016-01-13       Impact factor: 9.957
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