Literature DB >> 20632584

Performance evaluation of polycrystalline HgI2 photoconductors for radiation therapy imaging.

Qihua Zhao1, Larry E Antonuk, Youcef El-Mohri, Yi Wang, Hong Du, Amit Sawant, Zhong Su, Jin Yamamoto.   

Abstract

PURPOSE: Electronic portal imaging devices based on megavoltage (MV), active matrix, flat-panel imagers (AMFPIs) are presently regarded as the gold standard in portal imaging for external beam radiation therapy. These devices, employing indirect detection of incident radiation by means of a metal plate plus phosphor screen combination, offer a quantum efficiency of only approximately 2% at 6 MV, leading to a detective quantum efficiency (DQE) of only approximately 1%. In order to significantly improve the DQE performance of MV AMFPIs, a strategy based on the development of direct detection imagers incorporating thick films of polycrystalline mercuric iodide (HgI2) photoconductor was undertaken and is reported.
METHODS: Two MV AMFPI prototypes, one incorporating an approximately 300 microm thick HgI2 layer created through physical vapor deposition (PVD) and a second incorporating an approximately 460 microm thick HgI2 layer created through screen-printing of particle-in-binder (PIB) material, were quantitatively evaluated using a 6 MV photon beam. The reported measurements include empirical determination of x-ray sensitivity, lag, modulation transfer function (MTF), noise power spectrum, and DQE.
RESULTS: For both prototypes, MTF and DQE results were found to be consistent with theoretical expectations and the MTFs were also found to be higher than that measured from a conventional MV AMFPI. In addition, the DQE results exhibit input-quantum-limited behavior, even at extremely low doses. Compared to PVD, the PIB prototype exhibits much lower dark current, slightly higher lag, and similar DQE. Finally, the challenges associated with this approach, as well as strategies for achieving considerably higher DQE through thicker HgI2 layers, are discussed.
CONCLUSIONS: The DQE of each of the prototypes is found to be comparable to that of conventional MV AMFPIs, commensurate with the modest photoconductor thicknesses of these early samples. It is anticipated that thicker layers of HgI2 based on PIB deposition can provide higher DQE while maintaining good material properties.

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Year:  2010        PMID: 20632584      PMCID: PMC2885944          DOI: 10.1118/1.3416924

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  37 in total

1.  Monte Carlo study of a highly efficient gas ionization detector for megavoltage imaging and image-guided radiotherapy.

Authors:  H Keller; M Glass; R Hinderer; K Ruchala; R Jeraj; G Olivera; T Rock Mackie
Journal:  Med Phys       Date:  2002-02       Impact factor: 4.071

2.  Detective quantum efficiency of a direct-detection active matrix flat panel imager at megavoltage energies.

Authors:  M Lachaine; E Fourkal; B G Fallone
Journal:  Med Phys       Date:  2001-07       Impact factor: 4.071

3.  Systematic investigation of the signal properties of polycrystalline HgI2 detectors under mammographic, radiographic, fluoroscopic and radiotherapy irradiation conditions.

Authors:  Zhong Su; Larry E Antonuk; Youcef El-Mohri; Larry Hu; Hong Du; Amit Sawant; Yixin Li; Yi Wang; Jin Yamamoto; Qihua Zhao
Journal:  Phys Med Biol       Date:  2005-06-01       Impact factor: 3.609

4.  Monte Carlo investigations of megavoltage cone-beam CT using thick, segmented scintillating detectors for soft tissue visualization.

Authors:  Yi Wang; Larry E Antonuk; Youcef El-Mohri; Qihua Zhao; Amit Sawant; Hong Du
Journal:  Med Phys       Date:  2008-01       Impact factor: 4.071

5.  A simple method for determining the modulation transfer function in digital radiography.

Authors:  H Fujita; D Y Tsai; T Itoh; K Doi; J Morishita; K Ueda; A Ohtsuka
Journal:  IEEE Trans Med Imaging       Date:  1992       Impact factor: 10.048

6.  Initial performance evaluation of an indirect-detection, active matrix flat-panel imager (AMFPI) prototype for megavoltage imaging.

Authors:  L E Antonuk; Y El-Mohri; W Huang; K W Jee; J H Siewerdsen; M Maolinbay; V E Scarpine; H Sandler; J Yorkston
Journal:  Int J Radiat Oncol Biol Phys       Date:  1998-09-01       Impact factor: 7.038

7.  Monte Carlo detective quantum efficiency and scatter studies of a metal/a-Se portal detector.

Authors:  M Lachaîne; B G Fallone
Journal:  Med Phys       Date:  1998-07       Impact factor: 4.071

8.  Weekly localization films and detection of field placement errors.

Authors:  R W Byhardt; J D Cox; A Hornburg; G Liermann
Journal:  Int J Radiat Oncol Biol Phys       Date:  1978 Sep-Oct       Impact factor: 7.038

9.  Electronic and film portal images: a comparison of landmark visibility and review accuracy.

Authors:  Jon J Kruse; Michael G Herman; Chris R Hagness; Brian J Davis; Yolanda I Garces; Michael G Haddock; Kenneth R Olivier; Scott L Stafford; Thomas M Pisansky
Journal:  Int J Radiat Oncol Biol Phys       Date:  2002-10-01       Impact factor: 7.038

10.  Demonstration of megavoltage and diagnostic x-ray imaging with hydrogenated amorphous silicon arrays.

Authors:  L E Antonuk; J Boudry; W Huang; D L McShan; E J Morton; J Yorkston; M J Longo; R A Street
Journal:  Med Phys       Date:  1992 Nov-Dec       Impact factor: 4.071

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  6 in total

1.  Effect of detector lag on CT noise power spectra.

Authors:  Jongduk Baek; Norbert J Pelc
Journal:  Med Phys       Date:  2011-06       Impact factor: 4.071

2.  A novel multilayer MV imager computational model for component optimization.

Authors:  Marios Myronakis; Josh Star-Lack; Paul Baturin; Joerg Rottmann; Daniel Morf; Adam Wang; Yue-Houng Hu; Daniel Shedlock; Ross I Berbeco
Journal:  Med Phys       Date:  2017-06-28       Impact factor: 4.071

3.  Development of active matrix flat panel imagers incorporating thin layers of polycrystalline HgI(2) for mammographic x-ray imaging.

Authors:  Hao Jiang; Qihua Zhao; Larry E Antonuk; Youcef El-Mohri; Tapan Gupta
Journal:  Phys Med Biol       Date:  2013-01-14       Impact factor: 3.609

Review 4.  Amorphous and polycrystalline photoconductors for direct conversion flat panel x-ray image sensors.

Authors:  Safa Kasap; Joel B Frey; George Belev; Olivier Tousignant; Habib Mani; Jonathan Greenspan; Luc Laperriere; Oleksandr Bubon; Alla Reznik; Giovanni DeCrescenzo; Karim S Karim; John A Rowlands
Journal:  Sensors (Basel)       Date:  2011-05-09       Impact factor: 3.576

5.  Characterization of polycrystalline lead oxide for application in direct conversion X-ray detectors.

Authors:  O Semeniuk; O Grynko; G Decrescenzo; G Juska; K Wang; A Reznik
Journal:  Sci Rep       Date:  2017-08-17       Impact factor: 4.379

6.  Charge transport mechanism in lead oxide revealed by CELIV technique.

Authors:  O Semeniuk; G Juska; J-O Oelerich; M Wiemer; S D Baranovskii; A Reznik
Journal:  Sci Rep       Date:  2016-09-15       Impact factor: 4.379

  6 in total

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