Literature DB >> 20605453

Bilateral prophylactic mastectomy in women with inherited risk of breast cancer--prevalence of pain and discomfort, impact on sexuality, quality of life and feelings of regret two years after surgery.

Jessica Gahm1, Marie Wickman, Yvonne Brandberg.   

Abstract

BACKGROUND: Mastectomy due to breast cancer is associated with chronic pain and a negative impact on sexuality. The purposes of the study were to analyze the prevalence of pain and discomfort in the breasts, impact on sexuality, quality of life, and feelings of regret after bilateral prophylactic mastectomy and immediate reconstruction with implants.
METHODS: Fifty-nine women operated 2004-2006 were included. A questionnaire was sent out two years after the procedure. Complications and re-operations were recorded.
RESULTS: Mean follow-up time was 29 months. 93% of patients answered the questionnaire. 69% reported pain and 71% discomfort in the breasts. Lost or much reduced sexual sensations were reported by 85% and enjoyment of sex was negatively impacted for 75% of patients. Quality of life was not affected and feelings of regret were almost non-existent.
CONCLUSIONS: It is important to inform women approaching this prophylactic procedure about the risk of having unwanted secondary effects.
Copyright © 2010 Elsevier Ltd. All rights reserved.

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Year:  2010        PMID: 20605453     DOI: 10.1016/j.breast.2010.05.003

Source DB:  PubMed          Journal:  Breast        ISSN: 0960-9776            Impact factor:   4.380


  34 in total

1.  Uptake of a randomized breast cancer prevention trial comparing letrozole to placebo in BRCA1/2 mutations carriers: the LIBER trial.

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Journal:  Fam Cancer       Date:  2012-03       Impact factor: 2.375

2.  [Not Available].

Authors:  M W Gross; F B Zimmermann
Journal:  Strahlenther Onkol       Date:  2012-01       Impact factor: 3.621

3.  Body image issues after bilateral prophylactic mastectomy with breast reconstruction in healthy women at risk for hereditary breast cancer.

Authors:  Jessica P Gopie; Marc A M Mureau; Caroline Seynaeve; Moniek M Ter Kuile; Marian B E Menke-Pluymers; Reinier Timman; Aad Tibben
Journal:  Fam Cancer       Date:  2013-09       Impact factor: 2.375

4.  Local Therapy Decisional Regret in Older Women With Breast Cancer: A Population-Based Study.

Authors:  Pragati G Advani; Xiudong Lei; Cameron W Swanick; Ying Xu; Yu Shen; Nathan A Goodwin; Grace L Smith; Sharon H Giordano; Kelly K Hunt; Reshma Jagsi; Benjamin D Smith
Journal:  Int J Radiat Oncol Biol Phys       Date:  2019-02-01       Impact factor: 7.038

5.  Preoperative psychosocial characteristics may predict body image and sexuality two years after risk-reducing mastectomy: a prospective study.

Authors:  Dmytro Unukovych; Hemming Johansson; Yvonne Brandberg
Journal:  Gland Surg       Date:  2017-02

6.  Risk-Adjusted Prevention. Perspectives on the Governance of Entitlements to Benefits in the Case of Genetic (Breast Cancer) Risks.

Authors:  Friedhelm Meier; Anke Harney; Kerstin Rhiem; Silke Neusser; Anja Neumann; Matthias Braun; Jürgen Wasem; Stefan Huster; Peter Dabrock; Rita Katharina Schmutzler
Journal:  Recent Results Cancer Res       Date:  2021

7.  Trends in Use of Risk-Reducing Mastectomy in a Context of Celebrity Decisions and Media Coverage: An Observational Study in the United States and Australia.

Authors:  Jialin Mao; Louisa Jorm; Art Sedrakyan
Journal:  Health Serv Res       Date:  2017-09-25       Impact factor: 3.402

8.  Involvement and Influence of Healthcare Providers, Family Members, and Other Mutation Carriers in the Cancer Risk Management Decision-Making Process of BRCA1 and BRCA2 Mutation Carriers.

Authors:  Athena Puski; Shelly Hovick; Leigha Senter; Amanda Ewart Toland
Journal:  J Genet Couns       Date:  2018-03-29       Impact factor: 2.537

Review 9.  Quality of life among patients after bilateral prophylactic mastectomy: a systematic review of patient-reported outcomes.

Authors:  Shantanu N Razdan; Vishal Patel; Sarah Jewell; Colleen M McCarthy
Journal:  Qual Life Res       Date:  2015-11-14       Impact factor: 4.147

10.  Patient-Reported Outcomes Following Breast Reconstruction Surgery and Therapeutic Mammoplasty: Prospective Evaluation 1 Year Post-Surgery with BREAST-Q Questionnaire.

Authors:  Laxmi Shekhawat; Laleh Busheri; Santosh Dixit; Chaula Patel; Upendra Dhar; Chaitanyanand Koppiker
Journal:  Indian J Surg Oncol       Date:  2015-07-23
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