| Literature DB >> 20585442 |
Krzysztof W Fornalski1, Ludwik Dobrzyński.
Abstract
The linear no-threshold (LNT) dose-effect relationship has been consistently used by most radiation epidemiologists to estimate cancer mortality risk. The large scattering of data by International Agency for Research on Cancer, IARC (Vrijheid et al. 2007; Therry-Chef et al. 2007; Cardis et al. 2007), interpreted in accordance with LNT, has been previously demonstrated (Fornalski and Dobrzyński 2009). Using conventional and Bayesian methods the present paper demonstrates that the standard mortality ratios (SMRs), lower in the IARC cohort of exposed nuclear workers than in the non exposed group, should be considered as a hormetic effect, rather than a healthy worker effect (HWE) as claimed by the IARC group.Entities:
Keywords: Bayesian analysis; dose-response; healthy worker effect; hormesis; low radiation; nuclear industry workers
Year: 2010 PMID: 20585442 PMCID: PMC2889508 DOI: 10.2203/dose-response.09-019.Fornalski
Source DB: PubMed Journal: Dose Response ISSN: 1559-3258 Impact factor: 2.658