Literature DB >> 20543579

DNA methylation in endometrial cancer.

Meng Hua Tao1, Jo L Freudenheim.   

Abstract

Endometrial cancer is the most commonly diagnosed gynecological cancer, and it has been shown to be a complex disease driven by abnormal genetic, and epigenetic alterations, as well as environmental factors. Epigenetic changes resulting in aberrant gene expression are dynamic and modifiable features of many cancer types. A significant epigenetic change is aberrant DNA methylation. In this review, we review evidence on the role of aberrant DNA methylation, examining changes in relation to endometrial carcinogenesis, and report on recent advances in the understanding of the contribution of aberrant DNA methylation to endometrial cancer with the emphasis on the role of dietary/ lifestyle and environmental factors, as well as opportunities and challenges of DNA methylation in endometrial cancer management and prevention.

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Year:  2010        PMID： 20543579      PMCID： PMC2954259          DOI： 10.4161/epi.5.6.12431

Source DB:  PubMed          Journal:  Epigenetics        ISSN： 1559-2294            Impact factor:   4.528


  146 in total

1.  Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines.

Authors:  M F Kane; M Loda; G M Gaida; J Lipman; R Mishra; H Goldman; J M Jessup; R Kolodner
Journal:  Cancer Res       Date:  1997-03-01       Impact factor: 12.701

2.  Germline mutations in PTEN are present in Bannayan-Zonana syndrome.

Authors:  D J Marsh; P L Dahia; Z Zheng; D Liaw; R Parsons; R J Gorlin; C Eng
Journal:  Nat Genet       Date:  1997-08       Impact factor: 38.330

Review 3.  CpG islands and genes.

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Journal:  Curr Opin Genet Dev       Date:  1995-06       Impact factor: 5.578

4.  Clinical and pathological significance of microsatellite instability in sporadic endometrial carcinoma.

Authors:  R F Caduff; C M Johnston; S M Svoboda-Newman; E L Poy; S D Merajver; T S Frank
Journal:  Am J Pathol       Date:  1996-05       Impact factor: 4.307

5.  Microsatellite instability in cervical and endometrial carcinomas.

Authors:  A Helland; A L Børresen-Dale; P Peltomäki; M Hektoen; G B Kristensen; J M Nesland; A de la Chapelle; R A Lothe
Journal:  Int J Cancer       Date:  1997-03-04       Impact factor: 7.396

6.  Localization of the gene for Cowden disease to chromosome 10q22-23.

Authors:  M R Nelen; G W Padberg; E A Peeters; A Y Lin; B van den Helm; R R Frants; V Coulon; A M Goldstein; M M van Reen; D F Easton; R A Eeles; S Hodgsen; J J Mulvihill; V A Murday; M A Tucker; E C Mariman; T M Starink; B A Ponder; H H Ropers; H Kremer; M Longy; C Eng
Journal:  Nat Genet       Date:  1996-05       Impact factor: 38.330

7.  Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene.

Authors:  Y I Kim; I P Pogribny; A G Basnakian; J W Miller; J Selhub; S J James; J B Mason
Journal:  Am J Clin Nutr       Date:  1997-01       Impact factor: 7.045

8.  Microsatellite instability in endometrial carcinomas: frequent replication errors in tumors of early onset and/or of poorly differentiated type.

Authors:  K Kobayashi; S Sagae; R Kudo; H Saito; S Koi; Y Nakamura
Journal:  Genes Chromosomes Cancer       Date:  1995-10       Impact factor: 5.006

9.  Mutations in DNA mismatch repair genes are not responsible for microsatellite instability in most sporadic endometrial carcinomas.

Authors:  H Katabuchi; B van Rees; A R Lambers; B M Ronnett; M S Blazes; F S Leach; K R Cho; L Hedrick
Journal:  Cancer Res       Date:  1995-12-01       Impact factor: 12.701

10.  Mutational analysis of mismatch repair genes, hMLH1 and hMSH2, in sporadic endometrial carcinomas with microsatellite instability.

Authors:  K Kobayashi; M Matsushima; S Koi; H Saito; S Sagae; R Kudo; Y Nakamura
Journal:  Jpn J Cancer Res       Date:  1996-02
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  26 in total

1.  Epigenetic changes as prognostic predictors in endometrial carcinomas.

Authors:  Sanja A Farkas; Bengt G Sorbe; Torbjörn K Nilsson
Journal:  Epigenetics       Date:  2016-11-22       Impact factor: 4.528

2.  NEpiC: a network-assisted algorithm for epigenetic studies using mean and variance combined signals.

Authors:  Peifeng Ruan; Jing Shen; Regina M Santella; Shuigeng Zhou; Shuang Wang
Journal:  Nucleic Acids Res       Date:  2016-06-14       Impact factor: 16.971

3.  Proteogenomic Characterization of Endometrial Carcinoma.

Authors:  Yongchao Dou; Emily A Kawaler; Daniel Cui Zhou; Marina A Gritsenko; Chen Huang; Lili Blumenberg; Alla Karpova; Vladislav A Petyuk; Sara R Savage; Shankha Satpathy; Wenke Liu; Yige Wu; Chia-Feng Tsai; Bo Wen; Zhi Li; Song Cao; Jamie Moon; Zhiao Shi; MacIntosh Cornwell; Matthew A Wyczalkowski; Rosalie K Chu; Suhas Vasaikar; Hua Zhou; Qingsong Gao; Ronald J Moore; Kai Li; Sunantha Sethuraman; Matthew E Monroe; Rui Zhao; David Heiman; Karsten Krug; Karl Clauser; Ramani Kothadia; Yosef Maruvka; Alexander R Pico; Amanda E Oliphant; Emily L Hoskins; Samuel L Pugh; Sean J I Beecroft; David W Adams; Jonathan C Jarman; Andy Kong; Hui-Yin Chang; Boris Reva; Yuxing Liao; Dmitry Rykunov; Antonio Colaprico; Xi Steven Chen; Andrzej Czekański; Marcin Jędryka; Rafał Matkowski; Maciej Wiznerowicz; Tara Hiltke; Emily Boja; Christopher R Kinsinger; Mehdi Mesri; Ana I Robles; Henry Rodriguez; David Mutch; Katherine Fuh; Matthew J Ellis; Deborah DeLair; Mathangi Thiagarajan; D R Mani; Gad Getz; Michael Noble; Alexey I Nesvizhskii; Pei Wang; Matthew L Anderson; Douglas A Levine; Richard D Smith; Samuel H Payne; Kelly V Ruggles; Karin D Rodland; Li Ding; Bing Zhang; Tao Liu; David Fenyö
Journal:  Cell       Date:  2020-02-13       Impact factor: 41.582

4.  Detection of endometrial cancer via molecular analysis of DNA collected with vaginal tampons.

Authors:  Jamie N Bakkum-Gamez; Nicolas Wentzensen; Matthew J Maurer; Kieran M Hawthorne; Jesse S Voss; Trynda N Kroneman; Abimbola O Famuyide; Amy C Clayton; Kevin C Halling; Sarah E Kerr; William A Cliby; Sean C Dowdy; Benjamin R Kipp; Andrea Mariani; Ann L Oberg; Karl C Podratz; Viji Shridhar; Mark E Sherman
Journal:  Gynecol Oncol       Date:  2015-02-10       Impact factor: 5.482

Review 5.  Non-Coding RNAs in Endometrial Physiopathology.

Authors:  Alessandro La Ferlita; Rosalia Battaglia; Francesca Andronico; Salvatore Caruso; Antonio Cianci; Michele Purrello; Cinzia Di Pietro
Journal:  Int J Mol Sci       Date:  2018-07-20       Impact factor: 5.923

6.  Methylomic Analysis of Ovarian Cancers Identifies Tumor-Specific Alterations Readily Detectable in Early Precursor Lesions.

Authors:  Thomas R Pisanic; Leslie M Cope; Shiou-Fu Lin; Ting-Tai Yen; Pornpat Athamanolap; Ryoichi Asaka; Kentaro Nakayama; Amanda N Fader; Tza-Huei Wang; Ie-Ming Shih; Tian-Li Wang
Journal:  Clin Cancer Res       Date:  2018-08-14       Impact factor: 12.531

7.  One-carbon metabolism factors and endometrial cancer risk.

Authors:  J J Liu; A Hazra; E Giovannucci; S E Hankinson; B Rosner; I De Vivo
Journal:  Br J Cancer       Date:  2013-01-08       Impact factor: 7.640

8.  Risk factor analysis of coexisting endometrial carcinoma in patients with endometrial hyperplasia: a retrospective observational study of Taiwanese Gynecologic Oncology Group.

Authors:  Yu-Li Chen; Kung-Liahng Wang; Min-Yu Chen; Mu-Hsien Yu; Chen-Hsuan Wu; Yu-Min Ke; Yi-Jen Chen; Yin-Yi Chang; Keng-Fu Hsu; Ming-Shyen Yen
Journal:  J Gynecol Oncol       Date:  2013-01-08       Impact factor: 4.401

9.  Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development.

Authors:  Allison Jones; Andrew E Teschendorff; Quanxi Li; Jane D Hayward; Athilakshmi Kannan; Tim Mould; James West; Michal Zikan; David Cibula; Heidi Fiegl; Shih-Han Lee; Elisabeth Wik; Richard Hadwin; Rupali Arora; Charlotte Lemech; Henna Turunen; Päivi Pakarinen; Ian J Jacobs; Helga B Salvesen; Milan K Bagchi; Indrani C Bagchi; Martin Widschwendter
Journal:  PLoS Med       Date:  2013-11-12       Impact factor: 11.069

10.  Mutational landscape and significance across 12 major cancer types.

Authors:  Cyriac Kandoth; Michael D McLellan; Fabio Vandin; Kai Ye; Beifang Niu; Charles Lu; Mingchao Xie; Qunyuan Zhang; Joshua F McMichael; Matthew A Wyczalkowski; Mark D M Leiserson; Christopher A Miller; John S Welch; Matthew J Walter; Michael C Wendl; Timothy J Ley; Richard K Wilson; Benjamin J Raphael; Li Ding
Journal:  Nature       Date:  2013-10-17       Impact factor: 49.962
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