Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 A structure-activity relationship study of the antimalarial and antileishmanial activities of nonpeptide macrocyclic histone deacetylase inhibitors.

Literature DB >> 20533500

A structure-activity relationship study of the antimalarial and antileishmanial activities of nonpeptide macrocyclic histone deacetylase inhibitors.

William Guerrant¹, Sandra C Mwakwari, Po C Chen, Shabana I Khan, Babu L Tekwani, Adegboyega K Oyelere.

Abstract

Entities: CellLine Chemical Disease Gene Species

Mesh：

Substances：

Year: 2010 PMID： 20533500 PMCID： PMC3138184 DOI： 10.1002/cmdc.201000087

Source DB: PubMed Journal: ChemMedChem ISSN： 1860-7179 Impact factor: 3.466

× No keyword cloud information.

31 in total

Review 1. Epigenetic therapy of cancer: past, present and future.

Authors: Christine B Yoo; Peter A Jones
Journal: Nat Rev Drug Discov Date: 2006-01 Impact factor: 84.694

2. Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure-activity relationships of apicidin. Part 1.

Authors: S L Colletti; R W Myers; S J Darkin-Rattray; A M Gurnett; P M Dulski; S Galuska; J J Allocco; M B Ayer; C Li; J Lim; T M Crumley; C Cannova; D M Schmatz; M J Wyvratt; M H Fisher; P T Meinke
Journal: Bioorg Med Chem Lett Date: 2001-01-22 Impact factor: 2.823

3. A simple colorimetric method to screen drug cytotoxicity against Leishmania using the dye Alamar Blue.

Authors: J Mikus; D Steverding
Journal: Parasitol Int Date: 2000-01 Impact factor: 2.230

Review 4. Discovery and development of SAHA as an anticancer agent.

Authors: P A Marks
Journal: Oncogene Date: 2007-02-26 Impact factor: 9.867

5. Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase.

Authors: S J Darkin-Rattray; A M Gurnett; R W Myers; P M Dulski; T M Crumley; J J Allocco; C Cannova; P T Meinke; S L Colletti; M A Bednarek; S B Singh; M A Goetz; A W Dombrowski; J D Polishook; D M Schmatz
Journal: Proc Natl Acad Sci U S A Date: 1996-11-12 Impact factor: 11.205

6. Proof of interaction between Leishmania SIR2RP1 deacetylase and chaperone HSP83.

Authors: Monte-Alegre Adriano; Baptiste Vergnes; Joel Poncet; Françoise Mathieu-Daude; Anabela Cordeiro da Silva; Ali Ouaissi; Denis Sereno
Journal: Parasitol Res Date: 2006-11-10 Impact factor: 2.289

7. The global distribution of clinical episodes of Plasmodium falciparum malaria.

Authors: Robert W Snow; Carlos A Guerra; Abdisalan M Noor; Hla Y Myint; Simon I Hay
Journal: Nature Date: 2005-03-10 Impact factor: 49.962

8. Parasite lactate dehydrogenase as an assay for Plasmodium falciparum drug sensitivity.

Authors: M T Makler; J M Ries; J A Williams; J E Bancroft; R C Piper; B L Gibbins; D J Hinrichs
Journal: Am J Trop Med Hyg Date: 1993-06 Impact factor: 2.345

9. Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group.

Authors: Vishal Patil; William Guerrant; Po C Chen; Berkley Gryder; Derek B Benicewicz; Shabana I Khan; Babu L Tekwani; Adegboyega K Oyelere
Journal: Bioorg Med Chem Date: 2009-10-27 Impact factor: 3.641

10. Inhibition of Plasmodium falciparum proliferation in vitro by double-stranded RNA directed against malaria histone deacetylase.

Authors: N Sriwilaijaroen; S Boonma; P Attasart; J Pothikasikorn; S Panyim; W Noonpakdee
Journal: Biochem Biophys Res Commun Date: 2009-01-31 Impact factor: 3.575

3 in total