Literature DB >> 20489094

Normalized CT dose index of the CT scanners used in the National Lung Screening Trial.

Dianna D Cody1, Hyun-Jung Kim, Christopher H Cagnon, Frederick J Larke, Michael M McNitt-Gray, Randell L Kruger, Michael J Flynn, J Anthony Seibert, Philip F Judy, Xizeng Wu.   

Abstract

OBJECTIVE: The National Lung Screening Trial includes 33 participating institutions that performed 75,133 lung cancer screening CT examinations for 26,724 subjects during 2002-2007. For trial quality assurance reasons, CT radiation dose measurement data were collected from all MDCT scanners used in the trial.
MATERIALS AND METHODS: A total of 247 measurements on 96 MDCT scanners were collected using a standard CT dose index (CTDI) measurement protocol. The scan parameters used in the measurements (tube voltage, milliampere-seconds [mAs], and detector-channel configuration) were set according to trial protocol for average size subjects. The normalized weighted CT dose index (CTDI(w)) (computed as CTDI(w)/mAs) obtained from each trial-participating scanner was tabulated.
RESULTS: We found a statistically significant difference in normalized CT dose index among CT scanner manufacturers, likely as a result of design differences, such as filtration, bow-tie design, and geometry. Our findings also indicated a statistically significant difference in normalized CT dose index among CT scanner models from the same manufacturer (e.g., GE Healthcare, Siemens Healthcare, and Philips Healthcare). We also found a statistically significant difference in normalized CT dose index among all models and all manufacturers; furthermore, we found a statistically significant difference in normalized CT dose index among CT scanners from all manufacturers when we compared scanners with four or eight data channels to those with 16, 32, or 64 channels, suggesting that more complex scanners have improved dose efficiency.
CONCLUSION: Average normalized CT dose index values varied by a factor of almost two for all scanners from all manufacturers. This study was focused on machine-specific normalized CT dose index; patient dose and image quality were not addressed.

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Year:  2010        PMID: 20489094      PMCID: PMC3015146          DOI: 10.2214/AJR.09.3268

Source DB:  PubMed          Journal:  AJR Am J Roentgenol        ISSN: 0361-803X            Impact factor:   3.959


  7 in total

Review 1.  AAPM/RSNA Physics Tutorial for Residents: Topics in CT. Radiation dose in CT.

Authors:  Michael F McNitt-Gray
Journal:  Radiographics       Date:  2002 Nov-Dec       Impact factor: 5.333

2.  Estimated radiation risks potentially associated with full-body CT screening.

Authors:  David J Brenner; Carl D Elliston
Journal:  Radiology       Date:  2004-07-23       Impact factor: 11.105

3.  Description and implementation of a quality control program in an imaging-based clinical trial.

Authors:  Christopher H Cagnon; Dianna D Cody; Michael F McNitt-Gray; J Anthony Seibert; Philip F Judy; Denise R Aberle
Journal:  Acad Radiol       Date:  2006-11       Impact factor: 3.173

Review 4.  Mass screening with CT colonography: should the radiation exposure be of concern?

Authors:  David J Brenner; Maria A Georgsson
Journal:  Gastroenterology       Date:  2005-07       Impact factor: 22.682

5.  A method for describing the doses delivered by transmission x-ray computed tomography.

Authors:  T B Shope; R M Gagne; G C Johnson
Journal:  Med Phys       Date:  1981 Jul-Aug       Impact factor: 4.071

6.  Radiation risks potentially associated with low-dose CT screening of adult smokers for lung cancer.

Authors:  David J Brenner
Journal:  Radiology       Date:  2004-05       Impact factor: 11.105

Review 7.  The role of computed tomography in screening for cancer.

Authors:  Michael N Brant-Zawadzki
Journal:  Eur Radiol       Date:  2005-11       Impact factor: 5.315

  7 in total
  9 in total

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Journal:  Med Phys       Date:  2017-01       Impact factor: 4.071

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Authors:  Samuel G Armato; Geoffrey McLennan; Luc Bidaut; Michael F McNitt-Gray; Charles R Meyer; Anthony P Reeves; Binsheng Zhao; Denise R Aberle; Claudia I Henschke; Eric A Hoffman; Ella A Kazerooni; Heber MacMahon; Edwin J R Van Beeke; David Yankelevitz; Alberto M Biancardi; Peyton H Bland; Matthew S Brown; Roger M Engelmann; Gary E Laderach; Daniel Max; Richard C Pais; David P Y Qing; Rachael Y Roberts; Amanda R Smith; Adam Starkey; Poonam Batrah; Philip Caligiuri; Ali Farooqi; Gregory W Gladish; C Matilda Jude; Reginald F Munden; Iva Petkovska; Leslie E Quint; Lawrence H Schwartz; Baskaran Sundaram; Lori E Dodd; Charles Fenimore; David Gur; Nicholas Petrick; John Freymann; Justin Kirby; Brian Hughes; Alessi Vande Casteele; Sangeeta Gupte; Maha Sallamm; Michael D Heath; Michael H Kuhn; Ekta Dharaiya; Richard Burns; David S Fryd; Marcos Salganicoff; Vikram Anand; Uri Shreter; Stephen Vastagh; Barbara Y Croft
Journal:  Med Phys       Date:  2011-02       Impact factor: 4.071

Review 3.  Impact of low-dose computed tomography (LDCT) screening on lung cancer-related mortality.

Authors:  Asha Bonney; Reem Malouf; Corynne Marchal; David Manners; Kwun M Fong; Henry M Marshall; Louis B Irving; Renée Manser
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4.  Effective dose assessment for participants in the National Lung Screening Trial undergoing posteroanterior chest radiographic examinations.

Authors:  Randell Kruger; Michael J Flynn; Phillip F Judy; Christopher H Cagnon; J Anthony Seibert
Journal:  AJR Am J Roentgenol       Date:  2013-07       Impact factor: 3.959

5.  LoDoPaB-CT, a benchmark dataset for low-dose computed tomography reconstruction.

Authors:  Johannes Leuschner; Maximilian Schmidt; Daniel Otero Baguer; Peter Maass
Journal:  Sci Data       Date:  2021-04-16       Impact factor: 6.444

6.  Evaluation of radiation doses delivered in different chest CT protocols.

Authors:  Tomasz Gorycki; Iwona Lasek; Kamil Kamiński; Michał Studniarek
Journal:  Pol J Radiol       Date:  2014-01

7.  Assessment and comparison of radiation dose and image quality in multi-detector CT scanners in non-contrast head and neck examinations.

Authors:  Daryoush Khoramian; Soroush Sistani; Razzagh Abedi Firouzjah
Journal:  Pol J Radiol       Date:  2019-01-23

8.  Distribution of the radiation dose in multislice computer tomography of the chest - phantom study.

Authors:  Tomasz Gorycki; Kamil Kamiński; Michał Studniarek; Przemysław Szlęzak; Agnieszka Szumska
Journal:  Pol J Radiol       Date:  2014-04-14

9.  Multifactorial Analysis of Mortality in Screening Detected Lung Cancer.

Authors:  Subba R Digumarthy; Ruben De Man; Rodrigo Canellas; Alexi Otrakji; Ge Wang; Mannudeep K Kalra
Journal:  J Oncol       Date:  2018-05-16       Impact factor: 4.375

  9 in total

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