Literature DB >> 204601

The polypeptides of hepatitis A virus.

A G Coulepis, S A Locarnini, A A Ferris, N I Lehmann, I D Gust.   

Abstract

Hepatitis A virus was purified from fecal specimens obtained from 3 patients with naturally acquired hepatitis A, by a process of differential centrifugation, chloroform extraction, column chromatography, and isopycnic ultracentrifugation. Analysis of purified virus by discontinuous SDS-PAGE revealed three major polypeptides with molecular weights of 34,000, 25,500, and 23,000 daltons. These polypeptides appear to be specific for hepatitis A virus and have similar molecular weights to three of the four major polypeptides reported for members of the genus Enterovirus within the family Picornaviridae.

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Year:  1978        PMID： 204601     DOI： 10.1159/000148964

Source DB:  PubMed          Journal:  Intervirology        ISSN： 0300-5526            Impact factor:   1.763


  11 in total

1.  Primary structure and gene organization of human hepatitis A virus.

Authors:  R Najarian; D Caput; W Gee; S J Potter; A Renard; J Merryweather; G Van Nest; D Dina
Journal:  Proc Natl Acad Sci U S A       Date:  1985-05       Impact factor: 11.205

2.  Detection of hepatitis A virus and antibody by solid-phase radioimmunoassay and enzyme-linked immunosorbent assay with monoclonal antibodies.

Authors:  A G Coulepis; M F Veale; A MacGregor; M Kornitschuk; I D Gust
Journal:  J Clin Microbiol       Date:  1985-07       Impact factor: 5.948

3.  Structure of the hepatitis A virion: identification of potential surface-exposed regions.

Authors:  B H Robertson; V K Brown; B P Holloway; B Khanna; E Chan
Journal:  Arch Virol       Date:  1989       Impact factor: 2.574

4.  Evidence that the genome of hepatitis A virus consists of single-stranded RNA.

Authors:  A G Coulepis; G A Tannock; S A Locarnini; I D Gust
Journal:  J Virol       Date:  1981-01       Impact factor: 5.103

5.  Characterization and classification of virus particles associated with hepatitis A. III. Structural proteins.

Authors:  J D Tratschin; G Siegl; G G Frösner; F Deinhardt
Journal:  J Virol       Date:  1981-04       Impact factor: 5.103

6.  Monoclonal antibodies against hepatitis A virus.

Authors:  A MacGregor; M Kornitschuk; J G Hurrell; N I Lehmann; A G Coulepis; S A Locarnini; I D Gust
Journal:  J Clin Microbiol       Date:  1983-11       Impact factor: 5.948

7.  Solid-phase enzyme-linked immunosorbent assay for detection of hepatitis A-specific immunoglobulin M.

Authors:  S A Locarnini; A G Coulepis; A M Stratton; J Kaldor; I D Gust
Journal:  J Clin Microbiol       Date:  1979-04       Impact factor: 5.948

8.  Iodination of hepatitis A virus reveals a fourth structural polypeptide.

Authors:  A G Coulepis; S A Locarnini; I D Gust
Journal:  J Virol       Date:  1980-08       Impact factor: 5.103

9.  Coproantibodies in hepatitis A: detection by enzyme-linked immunosorbent assay and immune electron microscopy.

Authors:  S A Locarnini; A G Coulepis; J Kaldor; I D Gust
Journal:  J Clin Microbiol       Date:  1980-06       Impact factor: 5.948

10.  Propagation of human hepatitis A virus in African green monkey kidney cell culture: primary isolation and serial passage.

Authors:  R J Daemer; S M Feinstone; I D Gust; R H Purcell
Journal:  Infect Immun       Date:  1981-04       Impact factor: 3.441
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