Literature DB >> 20449610

Sex differences in laparoscopic cholecystectomy.

Simon E Thesbjerg1, Kirstine M Harboe, Linda Bardram, Jacob Rosenberg.   

Abstract

BACKGROUND: Conversion from laparoscopic to open cholecystectomy may not be desirable due to the increased complication rate and prolonged convalescence. In Denmark, nationwide data show that 7.7% of the laparoscopic cholecystectomies are converted to open surgery. This article aims to document the relationship of gender to conversion rate and length of hospital stay after laparoscopic cholecystectomy in a national cohort of patients.
METHODS: The gender of 5,951 patients from the 2007 National Danish Cholecystectomy Database was compared with conversion rate, length of hospital stay, and various risk factors using multivariate analyses.
RESULTS: The findings showed that 14.3% of the patients had acute cholecystitis and that men had the highest risk (odds ratio [OR], 1.94; 95% confidence interval [CI], 1.66-2.27). The operative findings for the men included sequelae from previous acute cholecystitis more frequently than the findings for the women (OR, 1.89; 95% CI, 1.67-2.15). The rate for conversion from laparoscopic to open surgery was 7.7%, and male sex was highly associated with conversion (OR, 2.48; 95% CI, 2.04-3.01). Thus, 259 (5.8%) of the 4,451 operations for women were converted to laparotomy compared with 199 (13.3%) of the 1,500 operations for men. No significant sex differences were found in the proportion of bile duct lesions (those requiring reconstructive surgery as well as those that could be handled by endoscopy or T-tube drainage, suturing, or both) or in the 30-day mortality rate. The multivariate analyses showed that male sex was a significant factor for conversion but not for length of postoperative stay or readmission.
CONCLUSION: Men showed a significantly higher risk of the operation being converted from laparoscopic to open cholecystectomy than women (OR, 2.48; 95% CI, 2.04-3.01). The main reason for this may be that men more frequently had acute cholecystitis or sequelae from previous acute cholecystitis. These results can be used to give patients a better basis for their informed consent and better resource management in connection with the operation.

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Year:  2010        PMID: 20449610     DOI: 10.1007/s00464-010-1091-1

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  22 in total

1.  Reasons for conversion from laparoscopic to open cholecystectomy: a 10-year review.

Authors:  Juliane Bingener-Casey; Melanie L Richards; William E Strodel; Wayne H Schwesinger; Kenneth R Sirinek
Journal:  J Gastrointest Surg       Date:  2002 Nov-Dec       Impact factor: 3.452

2.  Risk factors for conversion of laparoscopic cholecystectomy to open cholecystectomy.

Authors:  C Simopoulos; S Botaitis; A Polychronidis; G Tripsianis; A J Karayiannakis
Journal:  Surg Endosc       Date:  2005-05-04       Impact factor: 4.584

Review 3.  Conversions during laparoscopic cholecystectomy: risk factors and effects on patient outcome.

Authors:  Benjie Tang; Alfred Cuschieri
Journal:  J Gastrointest Surg       Date:  2006 Jul-Aug       Impact factor: 3.452

Review 4.  Laparoscopic versus open cholecystectomy for patients with symptomatic cholecystolithiasis.

Authors:  F Keus; J A F de Jong; H G Gooszen; C J H M van Laarhoven
Journal:  Cochrane Database Syst Rev       Date:  2006-10-18

5.  Symptomatic cholelithiasis: a different disease in men? Connecticut Laparoscopic Cholesystectomy Registry.

Authors:  J C Russell; S J Walsh; L Reed-Fourquet; A Mattie; J Lynch
Journal:  Ann Surg       Date:  1998-02       Impact factor: 12.969

6.  [Cholecystectomy in Denmark 1989-2003].

Authors:  Alan Patrick Ainsworth; Sven Adamsen; Jacob Rosenberg
Journal:  Ugeskr Laeger       Date:  2005-06-13

7.  Risk factors for conversion to open surgery in patients undergoing laparoscopic cholecystectomy.

Authors:  Salleh Ibrahim; Tay Khoon Hean; Lim Swee Ho; T Ravintharan; Tan Ngian Chye; Chng Hong Chee
Journal:  World J Surg       Date:  2006-09       Impact factor: 3.352

8.  A risk score for conversion from laparoscopic to open cholecystectomy.

Authors:  N A Kama; M Kologlu; M Doganay; E Reis; M Atli; M Dolapci
Journal:  Am J Surg       Date:  2001-06       Impact factor: 2.565

9.  Risk factors for perioperative complications in patients undergoing laparoscopic cholecystectomy: analysis of 22,953 consecutive cases from the Swiss Association of Laparoscopic and Thoracoscopic Surgery database.

Authors:  Urs F Giger; Jean-Marie Michel; Isabelle Opitz; Devdas Th Inderbitzin; Thomas Kocher; Lukas Krähenbühl
Journal:  J Am Coll Surg       Date:  2006-09-20       Impact factor: 6.113

10.  Surgical outcomes of open cholecystectomy in the laparoscopic era.

Authors:  Andrea S Wolf; Bram A Nijsse; Suzanne M Sokal; Yuchiao Chang; David L Berger
Journal:  Am J Surg       Date:  2008-10-16       Impact factor: 2.565

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  6 in total

1.  Open Cholecystectomy Has a Place in the Laparoscopic Era: a Retrospective Cohort Study.

Authors:  Ayman El Nakeeb; Youssef Mahdy; Aly Salem; Mohamed El Sorogy; Ahmed Abd El Rafea; Mohamed El Dosoky; Rami Said; Mohamed Abd Ellatif; Mohamed M A Alsayed
Journal:  Indian J Surg       Date:  2017-03-22       Impact factor: 0.656

2.  Gastrointestinal quality-of-life after cholecystectomy: indication predicts gastrointestinal symptoms and abdominal pain.

Authors:  Viktor Wanjura; Patrik Lundström; Johanna Osterberg; Ib Rasmussen; Britt-Marie Karlson; Gabriel Sandblom
Journal:  World J Surg       Date:  2014-12       Impact factor: 3.352

3.  The quality of cholecystectomy in Denmark: outcome and risk factors for 20,307 patients from the national database.

Authors:  Kirstine Moll Harboe; Linda Bardram
Journal:  Surg Endosc       Date:  2010-12-07       Impact factor: 4.584

4.  The use of patient factors to improve the prediction of operative duration using laparoscopic cholecystectomy.

Authors:  Cornelius A Thiels; Denny Yu; Amro M Abdelrahman; Elizabeth B Habermann; Susan Hallbeck; Kalyan S Pasupathy; Juliane Bingener
Journal:  Surg Endosc       Date:  2016-07-06       Impact factor: 4.584

5.  Is gallbladder inflammation more severe in male patients presenting with acute cholecystitis?

Authors:  Peter C Ambe; Sebastian A Weber; Dirk Wassenberg
Journal:  BMC Surg       Date:  2015-04-24       Impact factor: 2.102

6.  Preoperative administration of intramuscular dezocine reduces postoperative pain for laparoscopic cholecystectomy.

Authors:  Yaomin Zhu; Guixia Jing; Wei Yuan
Journal:  J Biomed Res       Date:  2011-09
  6 in total

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