INTRODUCTION AND HYPOTHESIS: This study seeks to compare the small intestine submucosa (SIS) graft with traditional colporrhaphy (TC) for surgical treatment of anterior vaginal prolapse. METHODS: Subjects were randomly assigned to SIS (n = 29) or to TC (n = 27) preoperatively and outcomes analyzed at 12 months postoperatively. The primary outcome was the absence of POP-Q stage >or= II prolapse, and secondary outcome was improvement in quality of life. Data were compared with independent samples or paired Student's t test. RESULTS:SIS group had 86.2% anatomic cure compared to 59.3% in TC (p = 0.03). SIS improved point Ba measurement significantly (-1.93 cm versus -1.37 cm, p = 0.02). Both operations significantly improved quality of life, although there were no differences between the groups. We observed a greater number of complications in the SIS group, with no infections or erosion. CONCLUSIONS:SIS repair improved point Ba significantly. However, there were no differences observed in quality of life between the techniques.
RCT Entities:
INTRODUCTION AND HYPOTHESIS: This study seeks to compare the small intestine submucosa (SIS) graft with traditional colporrhaphy (TC) for surgical treatment of anterior vaginal prolapse. METHODS: Subjects were randomly assigned to SIS (n = 29) or to TC (n = 27) preoperatively and outcomes analyzed at 12 months postoperatively. The primary outcome was the absence of POP-Q stage >or= II prolapse, and secondary outcome was improvement in quality of life. Data were compared with independent samples or paired Student's t test. RESULTS: SIS group had 86.2% anatomic cure compared to 59.3% in TC (p = 0.03). SIS improved point Ba measurement significantly (-1.93 cm versus -1.37 cm, p = 0.02). Both operations significantly improved quality of life, although there were no differences between the groups. We observed a greater number of complications in the SIS group, with no infections or erosion. CONCLUSIONS: SIS repair improved point Ba significantly. However, there were no differences observed in quality of life between the techniques.
Authors: Paulo Cezar Feldner; Lea Mina Kati; Marair Gracio Ferreira Sartori; Edmund Chada Baracat; Geraldo Rodrigues de Lima; Helena B Nader; Carl P Dietrich; Manoel João Batista Castello Girão Journal: Eur J Obstet Gynecol Reprod Biol Date: 2005-11-28 Impact factor: 2.435
Authors: Jeanette S Brown; L Elaine Waetjen; Leslee L Subak; David H Thom; Stephen Van den Eeden; Eric Vittinghoff Journal: Am J Obstet Gynecol Date: 2002-04 Impact factor: 8.661
Authors: Simone Dos Reis Brandão da Silveira; Jorge Milhem Haddad; Zsuzsanna Ilona Katalin de Jármy-Di Bella; Fernanda Nastri; Miriam Goncalves Markos Kawabata; Silvia da Silva Carramão; Claudinei Alves Rodrigues; Edmund Chada Baracat; Antonio Pedro Flores Auge Journal: Int Urogynecol J Date: 2014-09-09 Impact factor: 2.894