Literature DB >> 20428320

Synthesis of 8-Heteroaryl-2'-deoxyguanosine Derivatives.

Gerard Hobley1, Vladimir Gubala, María Del C Rivera-Sánchez, José M Rivera.   

Abstract

We describe the synthesis of 8-heteroaromatic-2'-deoxyguanosine analogues using Suzuki-Miyaura or Stille conditions. Unprotected and protected 8-bromo-2'-deoxyguanosine was coupled with commercially available heteroarylboronic acids or the trialkyltin derivatives of 2-pyridylbromides either with or without microwave irradiation in good yields.

Entities:  

Year:  2008        PMID： 20428320      PMCID： PMC2860324          DOI： 10.1055/s-2007-1077795

Source DB:  PubMed          Journal:  Synlett        ISSN： 0936-5214            Impact factor:   2.454


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3.  Walking a supramolecular tightrope: a self-assembled dodecamer from an 8-aryl-2'-deoxyguanosine derivative.

Authors:  María del C Rivera-Sánchez; Ivonne Andújar-de-Sanctis; Marilyn García-Arriaga; Vladimir Gubala; Gerard Hobley; José M Rivera
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