Literature DB >> 12443059

Preparation of C8-amine and acetylamine adducts of 2'-deoxyguanosine suitably protected for DNA synthesis.

Ludovic C J Gillet1, Orlando D Schärer.   

Abstract

[reaction: see text] C8-Amine and acetylamine adducts of 2'-deoxyguanosine were synthesized. Our approach provides solutions for the coupling of aromatic amines to a protected 8-bromo-2'-deoxyguanosine derivative, for the selective acetylation of the coupled adduct at N(8) and for a protecting group scheme preserving the integrity of the base-labile N(8) acetyl group during DNA synthesis.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12443059     DOI： 10.1021/ol026474f

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  20 in total

1.  Synthesis of 8-Heteroaryl-2'-deoxyguanosine Derivatives.

Authors:  Gerard Hobley; Vladimir Gubala; María Del C Rivera-Sánchez; José M Rivera
Journal:  Synlett       Date:  2008-06-01       Impact factor: 2.454

2.  Mechanism of replication blocking and bypass of Y-family polymerase {eta} by bulky acetylaminofluorene DNA adducts.

Authors:  Stephanie Schorr; Sabine Schneider; Katja Lammens; Karl-Peter Hopfner; Thomas Carell
Journal:  Proc Natl Acad Sci U S A       Date:  2010-11-12       Impact factor: 11.205

3.  Synthesis and thermodynamic studies of oligodeoxyribonucleotides containing tandem lesions of thymidine glycol and 8-oxo-2'-deoxyguanosine.

Authors:  Yuesong Wang; Yinsheng Wang
Journal:  Chem Res Toxicol       Date:  2006-06       Impact factor: 3.739

4.  Chemical and electrochemical oxidation of C8-arylamine adducts of 2'-deoxyguanosine.

Authors:  James S Stover; Madalina Ciobanu; David E Cliffel; Carmelo J Rizzo
Journal:  J Am Chem Soc       Date:  2007-01-26       Impact factor: 15.419

5.  Synthesis of oligonucleotides containing 2'-deoxyguanosine adducts of nitropyrenes.

Authors:  Laureen C Colis; Debasis Chakraborti; Pablo Hilario; Christopher McCarty; Ashis K Basu
Journal:  Nucleosides Nucleotides Nucleic Acids       Date:  2009-02       Impact factor: 1.381

6.  Tuning thermoresponsive supramolecular G-quadruplexes.

Authors:  José E Betancourt; José M Rivera
Journal:  Langmuir       Date:  2015-02-10       Impact factor: 3.882

7.  Structural insights into the recognition of cisplatin and AAF-dG lesion by Rad14 (XPA).

Authors:  Sandra C Koch; Jochen Kuper; Karola L Gasteiger; Nina Simon; Ralf Strasser; David Eisen; Simon Geiger; Sabine Schneider; Caroline Kisker; Thomas Carell
Journal:  Proc Natl Acad Sci U S A       Date:  2015-06-22       Impact factor: 11.205

8.  Mechanistic investigation of the bypass of a bulky aromatic DNA adduct catalyzed by a Y-family DNA polymerase.

Authors:  Varun V Gadkari; E John Tokarsky; Chanchal K Malik; Ashis K Basu; Zucai Suo
Journal:  DNA Repair (Amst)       Date:  2014-07-18

9.  Synthesis of Oligodeoxynucleotides Containing a C8-2'-Deoxyguanosine Adduct Formed by the Carcinogen 3-Nitrobenzanthrone.

Authors:  Arindom Chatterjee; Chanchal K Malik; Ashis K Basu
Journal:  Curr Protoc Nucleic Acid Chem       Date:  2017-06-19

10.  Synthesis of oligonucleotides containing the N2-deoxyguanosine adduct of the dietary carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline.

Authors:  James S Stover; Carmelo J Rizzo
Journal:  Chem Res Toxicol       Date:  2007-10-04       Impact factor: 3.739
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.