Literature DB >> 20418232

Endometrial carcinoma: controversies in histopathological assessment of grade and tumour cell type.

Blaise A Clarke1, C Blake Gilks.   

Abstract

Histopathological assessment of tumour grade and cell type is central to the management of endometrial carcinoma, guiding the extent of surgery and the use of adjuvant radiation therapy and chemotherapy. Endometrioid carcinomas are usually low grade but high-grade examples are encountered, and they have a significantly worse prognosis, similar to that of high-grade subtypes such as serous and clear cell carcinoma. This article reviews the various grading systems that have been proposed for use with endometrioid endometrial carcinoma, and discusses the recent progress in cell type assignment, including the use of immunohistochemistry as a diagnostic adjunct.

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Year:  2010        PMID： 20418232     DOI： 10.1136/jcp.2009.071225

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  29 in total

Review 1.  The emerging genomic landscape of endometrial cancer.

Authors:  Matthieu Le Gallo; Daphne W Bell
Journal:  Clin Chem       Date:  2013-10-29       Impact factor: 8.327

2.  FGFR2 mutations are associated with poor outcomes in endometrioid endometrial cancer: An NRG Oncology/Gynecologic Oncology Group study.

Authors:  Yvette W Jeske; Shamshad Ali; Sara A Byron; Feng Gao; Robert S Mannel; Rahel G Ghebre; Paul A DiSilvestro; Shashikant B Lele; Michael L Pearl; Amy P Schmidt; Heather A Lankes; Nilsa C Ramirez; Golnar Rasty; Matthew Powell; Paul J Goodfellow; Pamela M Pollock
Journal:  Gynecol Oncol       Date:  2017-03-15       Impact factor: 5.482

Review 3.  Prognostic biomarkers in endometrial and ovarian carcinoma.

Authors:  Xavier Matias-Guiu; Ben Davidson
Journal:  Virchows Arch       Date:  2014-02-07       Impact factor: 4.064

4.  Somatic mutation profiles of clear cell endometrial tumors revealed by whole exome and targeted gene sequencing.

Authors:  Matthieu Le Gallo; Meghan L Rudd; Mary Ellen Urick; Nancy F Hansen; Suiyuan Zhang; Fred Lozy; Dennis C Sgroi; August Vidal Bel; Xavier Matias-Guiu; Russell R Broaddus; Karen H Lu; Douglas A Levine; David G Mutch; Paul J Goodfellow; Helga B Salvesen; James C Mullikin; Daphne W Bell
Journal:  Cancer       Date:  2017-05-09       Impact factor: 6.860

5.  Does high-grade endometrioid carcinoma (grade 3 FIGO) belong to type I or type II endometrial cancer? A clinical-pathological and immunohistochemical study.

Authors:  Gian Franco Zannoni; Valerio Gaetano Vellone; Vincenzo Arena; Maria Grazia Prisco; Giovanni Scambia; Arnaldo Carbone; Daniela Gallo
Journal:  Virchows Arch       Date:  2010-06-15       Impact factor: 4.064

6.  Use of mutation profiles to refine the classification of endometrial carcinomas.

Authors:  Melissa K McConechy; Jiarui Ding; Maggie Cu Cheang; Kimberly Wiegand; Janine Senz; Alicia Tone; Winnie Yang; Leah Prentice; Kane Tse; Thomas Zeng; Helen McDonald; Amy P Schmidt; David G Mutch; Jessica N McAlpine; Martin Hirst; Sohrab P Shah; Cheng-Han Lee; Paul J Goodfellow; C Blake Gilks; David G Huntsman
Journal:  J Pathol       Date:  2012-07-18       Impact factor: 7.996

7.  L1CAM: amending the "low-risk" category in endometrial carcinoma.

Authors:  Felix Kommoss; Friedrich Kommoss; Friederike Grevenkamp; Anne-Kathrin Bunz; Florin-Andrei Taran; Falko Fend; Sara Y Brucker; Diethelm Wallwiener; Birgitt Schönfisch; Karen Greif; Sigurd Lax; Annette Staebler; Stefan Kommoss
Journal:  J Cancer Res Clin Oncol       Date:  2016-09-30       Impact factor: 4.553

Review 8.  [Grading of gynecological tumors : Current aspects].

Authors:  L-C Horn; D Mayr; C E Brambs; J Einenkel; I Sändig; K Schierle
Journal:  Pathologe       Date:  2016-07       Impact factor: 1.011

9.  High-resolution copy number analysis of clear cell endometrial carcinoma.

Authors:  Andrea J O'Hara; Matthieu Le Gallo; Meghan L Rudd; Daphne W Bell
Journal:  Cancer Genet       Date:  2019-10-21

10.  Determination of CA-125 levels in the serum, cervical and vaginal secretions, and endometrium in Chinese women with precancerous disease or endometrial cancer.

Authors:  Shu-Ming He; Fuqi Xing; Hong Sui; Youming Wu; Yongli Wang; Dong Wang; Guanghui Chen; Zijing Kong; Shu-Feng Zhou
Journal:  Med Sci Monit       Date:  2011-11
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