Literature DB >> 20379206

Role of GW182 proteins and PABPC1 in the miRNA pathway: a sense of déjà vu.

Felix Tritschler1, Eric Huntzinger, Elisa Izaurralde.   

Abstract

GW182 proteins have emerged as key components of microRNA (miRNA) silencing complexes in animals. Although the precise molecular function of GW182 proteins is not fully understood, new findings indicate that they act as poly(A)-binding protein (PABP)-interacting proteins (PAIPs) that promote gene silencing, at least in part, by interfering with cytoplasmic PABP1 (PABPC1) function during translation and mRNA stabilization. This recent discovery paves the way for future studies of miRNA silencing mechanisms.

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Year:  2010        PMID： 20379206     DOI： 10.1038/nrm2885

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  52 in total

Review 1.  P bodies: at the crossroads of post-transcriptional pathways.

Authors:  Ana Eulalio; Isabelle Behm-Ansmant; Elisa Izaurralde
Journal:  Nat Rev Mol Cell Biol       Date:  2007-01       Impact factor: 94.444

2.  P-body formation is a consequence, not the cause, of RNA-mediated gene silencing.

Authors:  Ana Eulalio; Isabelle Behm-Ansmant; Daniel Schweizer; Elisa Izaurralde
Journal:  Mol Cell Biol       Date:  2007-04-02       Impact factor: 4.272

3.  MicroRNAs direct rapid deadenylation of mRNA.

Authors:  Ligang Wu; Jihua Fan; Joel G Belasco
Journal:  Proc Natl Acad Sci U S A       Date:  2006-02-22       Impact factor: 11.205

Review 4.  Getting to the root of miRNA-mediated gene silencing.

Authors:  Ana Eulalio; Eric Huntzinger; Elisa Izaurralde
Journal:  Cell       Date:  2008-01-11       Impact factor: 41.582

5.  Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression.

Authors:  Agnieszka Zdanowicz; Rolf Thermann; Joanna Kowalska; Jacek Jemielity; Kent Duncan; Thomas Preiss; Edward Darzynkiewicz; Matthias W Hentze
Journal:  Mol Cell       Date:  2009-09-24       Impact factor: 17.970

6.  Structural basis of ligand recognition by PABC, a highly specific peptide-binding domain found in poly(A)-binding protein and a HECT ubiquitin ligase.

Authors:  Guennadi Kozlov; Gregory De Crescenzo; Nadia S Lim; Nadeem Siddiqui; Daniel Fantus; Avak Kahvejian; Jean-François Trempe; Demetra Elias; Irena Ekiel; Nahum Sonenberg; Maureen O'Connor-McCourt; Kalle Gehring
Journal:  EMBO J       Date:  2003-12-18       Impact factor: 11.598

7.  Molecular determinants of PAM2 recognition by the MLLE domain of poly(A)-binding protein.

Authors:  Guennadi Kozlov; Marie Ménade; Angelika Rosenauer; Long Nguyen; Kalle Gehring
Journal:  J Mol Biol       Date:  2010-01-22       Impact factor: 5.469

8.  Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation.

Authors:  Nader Ezzeddine; Tsung-Cheng Chang; Wenmiao Zhu; Akio Yamashita; Chyi-Ying A Chen; Zhenping Zhong; Yukiko Yamashita; Dinghai Zheng; Ann-Bin Shyu
Journal:  Mol Cell Biol       Date:  2007-09-04       Impact factor: 4.272

9.  RNA-directed DNA methylation requires an AGO4-interacting member of the SPT5 elongation factor family.

Authors:  Natacha Bies-Etheve; Dominique Pontier; Sylvie Lahmy; Claire Picart; Danielle Vega; Richard Cooke; Thierry Lagrange
Journal:  EMBO Rep       Date:  2009-04-03       Impact factor: 8.807

10.  Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs.

Authors:  Markus Landthaler; Dimos Gaidatzis; Andrea Rothballer; Po Yu Chen; Steven Joseph Soll; Lana Dinic; Tolulope Ojo; Markus Hafner; Mihaela Zavolan; Thomas Tuschl
Journal:  RNA       Date:  2008-10-31       Impact factor: 4.942
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  37 in total

Review 1.  Form, function, and regulation of ARGONAUTE proteins.

Authors:  Allison Mallory; Hervé Vaucheret
Journal:  Plant Cell       Date:  2010-12-23       Impact factor: 11.277

Review 2.  Germ Line Versus Soma in the Transition from Egg to Embryo.

Authors:  S Zachary Swartz; Gary M Wessel
Journal:  Curr Top Dev Biol       Date:  2015-08-19       Impact factor: 4.897

Review 3.  Gene silencing by microRNAs: contributions of translational repression and mRNA decay.

Authors:  Eric Huntzinger; Elisa Izaurralde
Journal:  Nat Rev Genet       Date:  2011-02       Impact factor: 53.242

Review 4.  Emerging mechanisms of mRNP remodeling regulation.

Authors:  Chyi-Ying A Chen; Ann-Bin Shyu
Journal:  Wiley Interdiscip Rev RNA       Date:  2014-06-12       Impact factor: 9.957

Review 5.  CBP80-promoted mRNP rearrangements during the pioneer round of translation, nonsense-mediated mRNA decay, and thereafter.

Authors:  L E Maquat; J Hwang; H Sato; Y Tang
Journal:  Cold Spring Harb Symp Quant Biol       Date:  2011-03-29

Review 6.  MicroRNA regulation by RNA-binding proteins and its implications for cancer.

Authors:  Marieke van Kouwenhove; Martijn Kedde; Reuven Agami
Journal:  Nat Rev Cancer       Date:  2011-08-05       Impact factor: 60.716

7.  Ethanol facilitates hepatitis C virus replication via up-regulation of GW182 and heat shock protein 90 in human hepatoma cells.

Authors:  Terence N Bukong; Wei Hou; Karen Kodys; Gyongyi Szabo
Journal:  Hepatology       Date:  2013-01       Impact factor: 17.425

Review 8.  Cytoplasmic deadenylation: regulation of mRNA fate.

Authors:  Katrin Wiederhold; Lori A Passmore
Journal:  Biochem Soc Trans       Date:  2010-12       Impact factor: 5.407

Review 9.  The physiological impact of microRNA gene regulation in the retina.

Authors:  Thomas R Sundermeier; Krzysztof Palczewski
Journal:  Cell Mol Life Sci       Date:  2012-03-30       Impact factor: 9.261

10.  Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate.

Authors:  Kai-Lieh Huang; Amanda B Chadee; Chyi-Ying A Chen; Yueqiang Zhang; Ann-Bin Shyu
Journal:  RNA       Date:  2013-01-22       Impact factor: 4.942
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