Literature DB >> 21118121

Cytoplasmic deadenylation: regulation of mRNA fate.

Katrin Wiederhold1, Lori A Passmore.   

Abstract

The poly(A) tail of mRNA has an important influence on the dynamics of gene expression. On one hand, it promotes enhanced mRNA stability to allow production of the protein, even after inactivation of transcription. On the other hand, shortening of the poly(A) tail (deadenylation) slows down translation of the mRNA, or prevents it entirely, by inducing mRNA decay. Thus deadenylation plays a crucial role in the post-transcriptional regulation of gene expression, deciding the fate of individual mRNAs. It acts both in basal mRNA turnover, as well as in temporally and spatially regulated translation and decay of specific mRNAs. In the present paper, we discuss mRNA deadenylation in eukaryotes, focusing on the main deadenylase, the Ccr4-Not complex, including its composition, regulation and functional roles.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 21118121      PMCID： PMC3890232          DOI： 10.1042/BST0381531

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN： 0300-5127            Impact factor:   5.407


  56 in total

1.  Deadenylation is a widespread effect of miRNA regulation.

Authors:  Ana Eulalio; Eric Huntzinger; Tadashi Nishihara; Jan Rehwinkel; Maria Fauser; Elisa Izaurralde
Journal:  RNA       Date:  2008-11-24       Impact factor: 4.942

2.  The Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferation.

Authors:  Akhmed Aslam; Saloni Mittal; Frederic Koch; Jean-Christophe Andrau; G Sebastiaan Winkler
Journal:  Mol Biol Cell       Date:  2009-07-15       Impact factor: 4.138

3.  Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.

Authors:  Marc R Fabian; Géraldine Mathonnet; Thomas Sundermeier; Hansruedi Mathys; Jakob T Zipprich; Yuri V Svitkin; Fabiola Rivas; Martin Jinek; James Wohlschlegel; Jennifer A Doudna; Chyi-Ying A Chen; Ann-Bin Shyu; John R Yates; Gregory J Hannon; Witold Filipowicz; Thomas F Duchaine; Nahum Sonenberg
Journal:  Mol Cell       Date:  2009-08-27       Impact factor: 17.970

4.  Ribosome association and stability of the nascent polypeptide-associated complex is dependent upon its own ubiquitination.

Authors:  Olesya O Panasenko; Fabrice P A David; Martine A Collart
Journal:  Genetics       Date:  2008-12-15       Impact factor: 4.562

5.  Structural basis of m(7)GpppG binding to poly(A)-specific ribonuclease.

Authors:  Mousheng Wu; Per Nilsson; Niklas Henriksson; Anna Niedzwiecka; Meng Kiat Lim; Zhihong Cheng; Kyriakos Kokkoris; Anders Virtanen; Haiwei Song
Journal:  Structure       Date:  2009-02-13       Impact factor: 5.006

6.  Nascent peptide-dependent translation arrest leads to Not4p-mediated protein degradation by the proteasome.

Authors:  Lyudmila N Dimitrova; Kazushige Kuroha; Tsuyako Tatematsu; Toshifumi Inada
Journal:  J Biol Chem       Date:  2009-02-09       Impact factor: 5.157

7.  Polyubiquitination of the demethylase Jhd2 controls histone methylation and gene expression.

Authors:  Douglas P Mersman; Hai-Ning Du; Ian M Fingerman; Paul F South; Scott D Briggs
Journal:  Genes Dev       Date:  2009-04-03       Impact factor: 11.361

8.  Co-translational mRNA decay in Saccharomyces cerevisiae.

Authors:  Wenqian Hu; Thomas J Sweet; Sangpen Chamnongpol; Kristian E Baker; Jeff Coller
Journal:  Nature       Date:  2009-08-23       Impact factor: 49.962

9.  microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells.

Authors:  Traude H Beilharz; David T Humphreys; Jennifer L Clancy; Rolf Thermann; David I K Martin; Matthias W Hentze; Thomas Preiss
Journal:  PLoS One       Date:  2009-08-27       Impact factor: 3.240

10.  Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps.

Authors:  Chyi-Ying A Chen; Dinghai Zheng; Zhenfang Xia; Ann-Bin Shyu
Journal:  Nat Struct Mol Biol       Date:  2009-10-18       Impact factor: 15.369
View more
  36 in total

1.  Cnot1, Cnot2, and Cnot3 maintain mouse and human ESC identity and inhibit extraembryonic differentiation.

Authors:  Xiaofeng Zheng; Raluca Dumitru; Brad L Lackford; Johannes M Freudenberg; Ajeet P Singh; Trevor K Archer; Raja Jothi; Guang Hu
Journal:  Stem Cells       Date:  2012-05       Impact factor: 6.277

2.  BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.

Authors:  Etienne Coyaud; Monika Mis; Estelle M N Laurent; Wade H Dunham; Amber L Couzens; Melanie Robitaille; Anne-Claude Gingras; Stephane Angers; Brian Raught
Journal:  Mol Cell Proteomics       Date:  2015-04-21       Impact factor: 5.911

3.  Uncoupling of mRNA synthesis and degradation impairs adaptation to host temperature in Cryptococcus neoformans.

Authors:  Amanda L M Bloom; J T Graham Solomons; Virginia E Havel; John C Panepinto
Journal:  Mol Microbiol       Date:  2013-06-03       Impact factor: 3.501

4.  A novel feedback loop regulates the response to endoplasmic reticulum stress via the cooperation of cytoplasmic splicing and mRNA translation.

Authors:  Mithu Majumder; Charlie Huang; Martin D Snider; Anton A Komar; Junichi Tanaka; Randal J Kaufman; Dawid Krokowski; Maria Hatzoglou
Journal:  Mol Cell Biol       Date:  2012-01-03       Impact factor: 4.272

5.  PolyA-specific ribonuclease (PARN-1) function in stage-specific mRNA turnover in Trypanosoma brucei.

Authors:  Christopher J Utter; Stacey A Garcia; Joseph Milone; Vivian Bellofatto
Journal:  Eukaryot Cell       Date:  2011-07-08

6.  C2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complex.

Authors:  Fabienne Mauxion; Brigitte Prève; Bertrand Séraphin
Journal:  RNA Biol       Date:  2012-12-11       Impact factor: 4.652

Review 7.  The biology of the germ line in echinoderms.

Authors:  Gary M Wessel; Lynae Brayboy; Tara Fresques; Eric A Gustafson; Nathalie Oulhen; Isabela Ramos; Adrian Reich; S Zachary Swartz; Mamiko Yajima; Vanessa Zazueta
Journal:  Mol Reprod Dev       Date:  2014-07-22       Impact factor: 2.609

Review 8.  The long and the short of it: the role of the zinc finger polyadenosine RNA binding protein, Nab2, in control of poly(A) tail length.

Authors:  Sharon Soucek; Anita H Corbett; Milo B Fasken
Journal:  Biochim Biophys Acta       Date:  2012-03-28

Review 9.  AUF1 regulation of coding and noncoding RNA.

Authors:  Elizabeth J F White; Aerielle E Matsangos; Gerald M Wilson
Journal:  Wiley Interdiscip Rev RNA       Date:  2016-09-13       Impact factor: 9.957

Review 10.  The fate of the messenger is pre-determined: a new model for regulation of gene expression.

Authors:  Gal Haimovich; Mordechai Choder; Robert H Singer; Tatjana Trcek
Journal:  Biochim Biophys Acta       Date:  2013-01-19
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.