| Literature DB >> 20354804 |
Keiichi Matsuzaki1, Rie Ishii, Kaori Kobiyama, Susumu Kitanaka.
Abstract
New benzophenone and flavonol galloyl glycosides were isolated from an 80% MeOH extract of Psidium guajava L. (Myrtaceae) together with five known quercetin glycosides. The structures of the novel glycosides were elucidated to be 2,4,6-trihydroxybenzophenone 4-O-(6''-O-galloyl)-beta-D: -glucopyranoside (1, guavinoside A), 2,4,6-trihydroxy-3,5-dimethylbenzophenone 4-O-(6''-O-galloyl)-beta-D: -glucopyranoside (2, guavinoside B), and quercetin 3-O-(5''-O-galloyl)-alpha-L: -arabinofuranoside (3, guavinoside C) by NMR, MS, UV, and IR spectroscopies. Isolated phenolic glycosides showed significant inhibitory activities against histamine release from rat peritoneal mast cells, and nitric oxide production from a murine macrophage-like cell line, RAW 264.7.Entities:
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Year: 2010 PMID： 20354804 PMCID： PMC2877814 DOI： 10.1007/s11418-010-0400-2
Source DB: PubMed Journal: J Nat Med ISSN： 1340-3443 Impact factor: 2.343