Literature DB >> 20348961

Unlocking the pathogenesis of celiac disease.

Robert M Plenge.   

Abstract

A genome-wide association study reports more than a dozen new susceptibility loci for celiac disease. Analysis of eQTL data from these and previously established risk loci sheds light on the genetic pathways underlying this common autoimmune disease.

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Year:  2010        PMID： 20348961     DOI： 10.1038/ng0410-281

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  7 in total

Review 1.  Detecting shared pathogenesis from the shared genetics of immune-related diseases.

Authors:  Alexandra Zhernakova; Cleo C van Diemen; Cisca Wijmenga
Journal:  Nat Rev Genet       Date:  2009-01       Impact factor: 53.242

Review 2.  Genetic mapping in human disease.

Authors:  David Altshuler; Mark J Daly; Eric S Lander
Journal:  Science       Date:  2008-11-07       Impact factor: 47.728

3.  Multiple common variants for celiac disease influencing immune gene expression.

Authors:  Patrick C A Dubois; Gosia Trynka; Lude Franke; Karen A Hunt; Jihane Romanos; Alessandra Curtotti; Alexandra Zhernakova; Graham A R Heap; Róza Adány; Arpo Aromaa; Maria Teresa Bardella; Leonard H van den Berg; Nicholas A Bockett; Emilio G de la Concha; Bárbara Dema; Rudolf S N Fehrmann; Miguel Fernández-Arquero; Szilvia Fiatal; Elvira Grandone; Peter M Green; Harry J M Groen; Rhian Gwilliam; Roderick H J Houwen; Sarah E Hunt; Katri Kaukinen; Dermot Kelleher; Ilma Korponay-Szabo; Kalle Kurppa; Padraic MacMathuna; Markku Mäki; Maria Cristina Mazzilli; Owen T McCann; M Luisa Mearin; Charles A Mein; Muddassar M Mirza; Vanisha Mistry; Barbara Mora; Katherine I Morley; Chris J Mulder; Joseph A Murray; Concepción Núñez; Elvira Oosterom; Roel A Ophoff; Isabel Polanco; Leena Peltonen; Mathieu Platteel; Anna Rybak; Veikko Salomaa; Joachim J Schweizer; Maria Pia Sperandeo; Greetje J Tack; Graham Turner; Jan H Veldink; Wieke H M Verbeek; Rinse K Weersma; Victorien M Wolters; Elena Urcelay; Bozena Cukrowska; Luigi Greco; Susan L Neuhausen; Ross McManus; Donatella Barisani; Panos Deloukas; Jeffrey C Barrett; Paivi Saavalainen; Cisca Wijmenga; David A van Heel
Journal:  Nat Genet       Date:  2010-02-28       Impact factor: 38.330

4.  Newly identified genetic risk variants for celiac disease related to the immune response.

Authors:  Karen A Hunt; Alexandra Zhernakova; Graham Turner; Graham A R Heap; Lude Franke; Marcel Bruinenberg; Jihane Romanos; Lotte C Dinesen; Anthony W Ryan; Davinder Panesar; Rhian Gwilliam; Fumihiko Takeuchi; William M McLaren; Geoffrey K T Holmes; Peter D Howdle; Julian R F Walters; David S Sanders; Raymond J Playford; Gosia Trynka; Chris J J Mulder; M Luisa Mearin; Wieke H M Verbeek; Valerie Trimble; Fiona M Stevens; Colm O'Morain; Nicholas P Kennedy; Dermot Kelleher; Daniel J Pennington; David P Strachan; Wendy L McArdle; Charles A Mein; Martin C Wapenaar; Panos Deloukas; Ralph McGinnis; Ross McManus; Cisca Wijmenga; David A van Heel
Journal:  Nat Genet       Date:  2008-03-02       Impact factor: 38.330

5.  Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer.

Authors:  L M Sollid; G Markussen; J Ek; H Gjerde; F Vartdal; E Thorsby
Journal:  J Exp Med       Date:  1989-01-01       Impact factor: 14.307

6.  Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.

Authors:  Soumya Raychaudhuri; Robert M Plenge; Elizabeth J Rossin; Aylwin C Y Ng; Shaun M Purcell; Pamela Sklar; Edward M Scolnick; Ramnik J Xavier; David Altshuler; Mark J Daly
Journal:  PLoS Genet       Date:  2009-06-26       Impact factor: 5.917

7.  A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.

Authors:  David A van Heel; Lude Franke; Karen A Hunt; Rhian Gwilliam; Alexandra Zhernakova; Mike Inouye; Martin C Wapenaar; Martin C N M Barnardo; Graeme Bethel; Geoffrey K T Holmes; Con Feighery; Derek Jewell; Dermot Kelleher; Parveen Kumar; Simon Travis; Julian R F Walters; David S Sanders; Peter Howdle; Jill Swift; Raymond J Playford; William M McLaren; M Luisa Mearin; Chris J Mulder; Ross McManus; Ralph McGinnis; Lon R Cardon; Panos Deloukas; Cisca Wijmenga
Journal:  Nat Genet       Date:  2007-06-10       Impact factor: 38.330
  7 in total
  4 in total

Review 1.  Zonulin, regulation of tight junctions, and autoimmune diseases.

Authors:  Alessio Fasano
Journal:  Ann N Y Acad Sci       Date:  2012-07       Impact factor: 5.691

Review 2.  Effect of wheat grain protein composition on end-use quality.

Authors:  Ambika Sharma; Sheenu Garg; Imran Sheikh; Pritesh Vyas; H S Dhaliwal
Journal:  J Food Sci Technol       Date:  2020-01-04       Impact factor: 2.701

Review 3.  Leaky gut and autoimmune diseases.

Authors:  Alessio Fasano
Journal:  Clin Rev Allergy Immunol       Date:  2012-02       Impact factor: 8.667

4.  Identifying the genetic variation of gene expression using gene sets: application of novel gene Set eQTL approach to PharmGKB and KEGG.

Authors:  Ryan Abo; Gregory D Jenkins; Liewei Wang; Brooke L Fridley
Journal:  PLoS One       Date:  2012-08-14       Impact factor: 3.240
  4 in total

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