Literature DB >> 20189100

Nucleic acid detection using MNAzymes.

Yulia V Gerasimova1, Dmitry M Kolpashchikov.   

Abstract

Deoxyribozymes are promising biotechnological tools. In a recent JACS article, Mokany et al. reported on the design of multi-component deoxyribozyme (MNAzyme) sensors based on 10-23 and 8-17 DNA enzymes. The sensors can detect down to 5 pM of a specific nucleic acid. The versatility of MNAzyme platform allows the design of catalytic cascades for signal amplification. This work is a step forward to PCR-free molecular diagnostics. Copyright 2010 Elsevier Ltd. All rights reserved.

Entities:  

Year:  2010        PMID: 20189100      PMCID: PMC2890288          DOI: 10.1016/j.chembiol.2010.02.003

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  9 in total

1.  Exponential growth by cross-catalytic cleavage of deoxyribozymogens.

Authors:  Matthew Levy; Andrew D Ellington
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-12       Impact factor: 11.205

2.  Split DNA enzyme for visual single nucleotide polymorphism typing.

Authors:  Dmitry M Kolpashchikov
Journal:  J Am Chem Soc       Date:  2008-02-19       Impact factor: 15.419

Review 3.  Functional nucleic acid sensors.

Authors:  Juewen Liu; Zehui Cao; Yi Lu
Journal:  Chem Rev       Date:  2009-05       Impact factor: 60.622

Review 4.  Biologically inspired synthetic enzymes made from DNA.

Authors:  Kenny Schlosser; Yingfu Li
Journal:  Chem Biol       Date:  2009-03-27

Review 5.  Deoxyribozymes: useful DNA catalysts in vitro and in vivo.

Authors:  D A Baum; S K Silverman
Journal:  Cell Mol Life Sci       Date:  2008-07       Impact factor: 9.261

6.  A binary deoxyribozyme for nucleic acid analysis.

Authors:  Dmitry M Kolpashchikov
Journal:  Chembiochem       Date:  2007-11-23       Impact factor: 3.164

7.  Mechanism and utility of an RNA-cleaving DNA enzyme.

Authors:  S W Santoro; G F Joyce
Journal:  Biochemistry       Date:  1998-09-22       Impact factor: 3.162

8.  A DNA enzyme that cleaves RNA.

Authors:  R R Breaker; G F Joyce
Journal:  Chem Biol       Date:  1994-12

9.  Increased risk of mother-to-infant transmission of hepatitis C virus by intrapartum infantile exposure to maternal blood.

Authors:  Christoph Steininger; Michael Kundi; Gerlinde Jatzko; Herbert Kiss; Andreas Lischka; Heidemarie Holzmann
Journal:  J Infect Dis       Date:  2003-01-08       Impact factor: 5.226

  9 in total
  15 in total

1.  FaptaSyme: A Strategy for Converting a Monomer/Oligomer-Nonselective Aptameric Sensor into an Oligomer-Selective One.

Authors:  Baggio A Evangelista; Yoon-Seong Kim; Dmitry M Kolpashchikov
Journal:  Chembiochem       Date:  2018-04-26       Impact factor: 3.164

2.  Label-Free Pathogen Detection by a Deoxyribozyme Cascade with Visual Signal Readout.

Authors:  Adam J Reed; Ryan P Connelly; Allison Williams; Maithi Tran; Byoung-Shik Shim; Hyeryun Choe; Yulia V Gerasimova
Journal:  Sens Actuators B Chem       Date:  2018-11-29       Impact factor: 7.460

3.  DNA nanotechnology for nucleic acid analysis: multifunctional molecular DNA machine for RNA detection.

Authors:  A J Cox; H N Bengtson; K H Rohde; D M Kolpashchikov
Journal:  Chem Commun (Camb)       Date:  2016-12-06       Impact factor: 6.222

4.  Multiplex detection of extensively drug resistant tuberculosis using binary deoxyribozyme sensors.

Authors:  Hillary N Bengtson; Susanne Homolka; Stefan Niemann; Ana Júlia Reis; Pedro Eduardo da Silva; Yulia V Gerasimova; Dmitry M Kolpashchikov; Kyle H Rohde
Journal:  Biosens Bioelectron       Date:  2017-03-01       Impact factor: 10.618

5.  Bridging the Two Worlds: A Universal Interface between Enzymatic and DNA Computing Systems.

Authors:  Shay Mailloux; Yulia V Gerasimova; Nataliia Guz; Dmitry M Kolpashchikov; Evgeny Katz
Journal:  Angew Chem Int Ed Engl       Date:  2015-04-09       Impact factor: 15.336

6.  Species Typing of Nontuberculous Mycobacteria by Use of Deoxyribozyme Sensors.

Authors:  Hillary N Wood; Ashelyn E Sidders; Lauren E Brumsey; Evgeny S Morozkin; Yulia V Gerasimova; Kyle H Rohde
Journal:  Clin Chem       Date:  2018-12-06       Impact factor: 8.327

7.  A mutation-resistant deoxyribozyme OR gate for highly selective detection of viral nucleic acids.

Authors:  Ola Kamar; Sin-Cih Sun; Chieh-Hua Lin; Wan-Yu Chung; Min-Shi Lee; Yu-Chieh Liao; Dmitry M Kolpashchikov; Min-Chieh Chuang
Journal:  Chem Commun (Camb)       Date:  2017-09-21       Impact factor: 6.222

8.  DNA Antenna Tile-Associated Deoxyribozyme Sensor with Improved Sensitivity.

Authors:  Amanda J Cox; Hillary N Bengtson; Yulia V Gerasimova; Kyle H Rohde; Dmitry M Kolpashchikov
Journal:  Chembiochem       Date:  2016-09-13       Impact factor: 3.164

9.  Divide and Control: Comparison of Split and Switch Hybridization Sensors.

Authors:  Alexandra L Smith; Dmitry M Kolpashchikov
Journal:  ChemistrySelect       Date:  2017-07-04       Impact factor: 2.109

10.  DNA Computing Systems Activated by Electrochemically-triggered DNA Release from a Polymer-brush-modified Electrode Array.

Authors:  Maria Gamella; Andrey Zakharchenko; Nataliia Guz; Madeline Masi; Sergiy Minko; Dmitry M Kolpashchikov; Heiko Iken; Arshak Poghossian; Michael J Schöning; Evgeny Katz
Journal:  Electroanalysis       Date:  2016-08-05       Impact factor: 3.223

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