Literature DB >> 20159444

Imaging the human medial temporal lobe with high-resolution fMRI.

Valerie A Carr1, Jesse Rissman, Anthony D Wagner.   

Abstract

High-resolution functional MRI (hr-fMRI) affords unique leverage on the functional properties of human medial temporal lobe (MTL) substructures. We review initial hr-fMRI efforts to delineate (1) encoding and retrieval processes within the hippocampal circuit, (2) hippocampal subfield contributions to pattern separation and pattern completion, and (3) the representational capabilities of distinct MTL subregions. Extant data reveal functional heterogeneity within human MTL and highlight the promise of hr-fMRI for bridging human, animal, and computational approaches to understanding MTL function. Copyright 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID： 20159444      PMCID： PMC2844113          DOI： 10.1016/j.neuron.2009.12.022

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


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