Literature DB >> 20159344

Genetics of obsessive-compulsive disorder.

Gerald Nestadt1, Marco Grados, Jack F Samuels.   

Abstract

Obsessive-compulsive disorder is a common debilitating condition affecting individuals from childhood through adult life. There is good evidence of genetic contribution to its etiology, but environmental risk factors also are likely to be involved. The condition probably has a complex pattern of inheritance. Molecular studies have identified several potentially relevant genes, but much additional research is needed to establish definitive causes of the condition. Copyright 2010 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Year:  2010        PMID： 20159344      PMCID： PMC2824902          DOI： 10.1016/j.psc.2009.11.001

Source DB:  PubMed          Journal:  Psychiatr Clin North Am        ISSN： 0193-953X


  139 in total

Review 1.  Mapping complex disease loci in whole-genome association studies.

Authors:  Christopher S Carlson; Michael A Eberle; Leonid Kruglyak; Deborah A Nickerson
Journal:  Nature       Date:  2004-05-27       Impact factor: 49.962

2.  The future of association studies: gene-based analysis and replication.

Authors:  Benjamin M Neale; Pak C Sham
Journal:  Am J Hum Genet       Date:  2004-07-22       Impact factor: 11.025

3.  Association between the COMT locus and obsessive-compulsive disorder in females but not males.

Authors:  John P Alsobrook; Ada H Zohar; Marion Leboyer; Nadia Chabane; Richard P Ebstein; David L Pauls
Journal:  Am J Med Genet       Date:  2002-01-08

4.  Symptoms of obsessive-compulsive disorder.

Authors:  J F Leckman; D E Grice; J Boardman; H Zhang; A Vitale; C Bondi; J Alsobrook; B S Peterson; D J Cohen; S A Rasmussen; W K Goodman; C J McDougle; D L Pauls
Journal:  Am J Psychiatry       Date:  1997-07       Impact factor: 18.112

5.  Obsessive and compulsive symptoms in a general population sample of female twins.

Authors:  A H Jonnal; C O Gardner; C A Prescott; K S Kendler
Journal:  Am J Med Genet       Date:  2000-12-04

Review 6.  Multiple rare SAPAP3 missense variants in trichotillomania and OCD.

Authors:  S Züchner; J R Wendland; A E Ashley-Koch; A L Collins; K N Tran-Viet; K Quinn; K C Timpano; M L Cuccaro; M A Pericak-Vance; D C Steffens; K R Krishnan; G Feng; D L Murphy
Journal:  Mol Psychiatry       Date:  2009-01       Impact factor: 15.992

7.  Association of the SLC1A1 glutamate transporter gene and obsessive-compulsive disorder.

Authors:  S Evelyn Stewart; Jesen A Fagerness; Jill Platko; Jordan W Smoller; Jeremiah M Scharf; Cornelia Illmann; Eric Jenike; Nadia Chabane; Marion Leboyer; Richard Delorme; Michael A Jenike; David L Pauls
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2007-12-05       Impact factor: 3.568

8.  Distinct neural correlates of washing, checking, and hoarding symptom dimensions in obsessive-compulsive disorder.

Authors:  David Mataix-Cols; Sarah Wooderson; Natalia Lawrence; Michael J Brammer; Anne Speckens; Mary L Phillips
Journal:  Arch Gen Psychiatry       Date:  2004-06

9.  SERT Ileu425Val in autism, Asperger syndrome and obsessive-compulsive disorder.

Authors:  Jens R Wendland; Theresa B DeGuzman; Francis McMahon; Gary Rudnick; Sevilla D Detera-Wadleigh; Dennis L Murphy
Journal:  Psychiatr Genet       Date:  2008-02       Impact factor: 2.458

10.  Factor analysis of symptom subtypes of obsessive compulsive disorder and their relation to personality and tic disorders.

Authors:  L Baer
Journal:  J Clin Psychiatry       Date:  1994-03       Impact factor: 4.384
View more
  23 in total

Review 1.  Developmental plasticity and evolution--quo vadis?

Authors:  A P Moczek
Journal:  Heredity (Edinb)       Date:  2015-03-18       Impact factor: 3.821

2.  Association study of dopamine transporter gene (DAT1) variable tandem repeat sequence (VNTR) with obsessive-compulsive disorder in Chinese Han Population.

Authors:  Shaoyan Zhang; Weihua Jiang; Xiuming Tang; Quanchen Xu; Jingli Wang; Rui Gui; Xinhua Zhang; Shiguo Liu
Journal:  Int J Clin Exp Med       Date:  2015-03-15

3.  Comprehensive family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder.

Authors:  Jack Samuels; Ying Wang; Mark A Riddle; Benjamin D Greenberg; Abby J Fyer; James T McCracken; Scott L Rauch; Dennis L Murphy; Marco A Grados; James A Knowles; John Piacentini; Bernadette Cullen; O Joseph Bienvenu; Steven A Rasmussen; Daniel Geller; David L Pauls; Kung-Yee Liang; Yin Y Shugart; Gerald Nestadt
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2011-03-28       Impact factor: 3.568

Review 4.  Role of Sonic Hedgehog Signaling Activation in the Prevention of Neurological Abnormalities Associated with Obsessive-Compulsive Disorder.

Authors:  Ria Gupta; Sidharth Mehan; Swesha Chhabra; Aditi Giri; Kajal Sherawat
Journal:  Neurotox Res       Date:  2022-10-22       Impact factor: 3.978

5.  Sex differences in the genetic architecture of obsessive-compulsive disorder.

Authors:  Ekaterina A Khramtsova; Raphael Heldman; Eske M Derks; Dongmei Yu; Lea K Davis; Barbara E Stranger
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2018-11-20       Impact factor: 3.568

6.  The morphometric co-atrophy networking of schizophrenia, autistic and obsessive spectrum disorders.

Authors:  Franco Cauda; Andrea Nani; Tommaso Costa; Sara Palermo; Karina Tatu; Jordi Manuello; Sergio Duca; Peter T Fox; Roberto Keller
Journal:  Hum Brain Mapp       Date:  2018-01-18       Impact factor: 5.038

7.  Eighteen-year-old man with autism, obsessive compulsive disorder and a SHANK2 variant presents with severe anorexia that responds to high-dose fluoxetine.

Authors:  Zhen A Lu; Weiyi Mu; Lauren M Osborne; Zachary A Cordner
Journal:  BMJ Case Rep       Date:  2018-07-09

8.  Exome sequencing in obsessive-compulsive disorder reveals a burden of rare damaging coding variants.

Authors:  Gerald Nestadt; David B Goldstein; Mathew Halvorsen; Jack Samuels; Ying Wang; Benjamin D Greenberg; Abby J Fyer; James T McCracken; Daniel A Geller; James A Knowles; Anthony W Zoghbi; Tess D Pottinger; Marco A Grados; Mark A Riddle; O Joseph Bienvenu; Paul S Nestadt; Janice Krasnow; Fernando S Goes; Brion Maher
Journal:  Nat Neurosci       Date:  2021-06-28       Impact factor: 24.884

9.  Investigation of glycaemic traits in psychiatric disorders using Mendelian randomisation revealed a causal relationship with anorexia nervosa.

Authors:  Danielle M Adams; William R Reay; Michael P Geaghan; Murray J Cairns
Journal:  Neuropsychopharmacology       Date:  2020-09-13       Impact factor: 7.853

10.  Isoforms of the neuronal glutamate transporter gene, SLC1A1/EAAC1, negatively modulate glutamate uptake: relevance to obsessive-compulsive disorder.

Authors:  B Porton; B D Greenberg; K Askland; L M Serra; J Gesmonde; G Rudnick; S A Rasmussen; H-T Kao
Journal:  Transl Psychiatry       Date:  2013-05-21       Impact factor: 6.222
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.