Literature DB >> 9210740

Symptoms of obsessive-compulsive disorder.

J F Leckman1, D E Grice, J Boardman, H Zhang, A Vitale, C Bondi, J Alsobrook, B S Peterson, D J Cohen, S A Rasmussen, W K Goodman, C J McDougle, D L Pauls.   

Abstract

OBJECTIVE: Obsessive-compulsive disorder encompasses a broad range of symptoms that represent multiple psychological domains, including perception, cognition, emotion, social relatedness, and diverse motor behaviors. The purpose of these analyses was to evaluate the correlational relationships of the symptoms of obsessive-compulsive disorder.
METHOD: This study examined the 13 a priori categories used to group types of obsessions and compulsions in the Yale-Brown Obsessive Compulsive Scale symptom checklist in two independent groups of patients with obsessive-compulsive disorder (N = 208 and N = 98). A principal-components factor analysis with varimax rotation was performed, followed by a series of other exploratory analyses.
RESULTS: The two data sets yielded nearly identical results. Four factors--obsessions and checking, symmetry and ordering, cleanliness and washing, and boarding--emerged in each data set, in total accounting for more than 60% of the variance.
CONCLUSIONS: Obsessive-compulsive disorder is a multidimensional and etiologically heterogeneous condition. The four symptom dimensions identified in this study are largely congruent with those identified in earlier reports. These factors may be of value in future genetic, neurobiological, and treatment response studies.

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Year:  1997        PMID: 9210740     DOI: 10.1176/ajp.154.7.911

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN: 0002-953X            Impact factor:   18.112


  86 in total

Review 1.  The genetics of obsessive-compulsive disorder.

Authors:  M T Pato; K M Schindler; C N Pato
Journal:  Curr Psychiatry Rep       Date:  2001-04       Impact factor: 5.285

2.  Cognitive inflexibility and frontal-cortical activation in pediatric obsessive-compulsive disorder.

Authors:  Jennifer C Britton; Scott L Rauch; Isabelle M Rosso; William D S Killgore; Lauren M Price; Jennifer Ragan; Anne Chosak; Dianne M Hezel; Daniel S Pine; Ellen Leibenluft; David L Pauls; Michael A Jenike; S Evelyn Stewart
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2010-06-29       Impact factor: 8.829

Review 3.  The polyvagal perspective.

Authors:  Stephen W Porges
Journal:  Biol Psychol       Date:  2006-10-16       Impact factor: 3.251

4.  Genome scan for Tourette disorder in affected-sibling-pair and multigenerational families.

Authors: 
Journal:  Am J Hum Genet       Date:  2007-02       Impact factor: 11.025

5.  Temperamental factors in children and adolescents with obsessive-compulsive disorder (OCD) and in normal controls.

Authors:  Tord Ivarsson; Catharina Winge-Westholm
Journal:  Eur Child Adolesc Psychiatry       Date:  2004-12       Impact factor: 4.785

6.  Paroxetine treatment of compulsive hoarding.

Authors:  Sanjaya Saxena; Arthur L Brody; Karron M Maidment; Lewis R Baxter
Journal:  J Psychiatr Res       Date:  2006-06-21       Impact factor: 4.791

7.  Prevalence and clinical characteristics of mental rituals in a longitudinal clinical sample of obsessive-compulsive disorder.

Authors:  Nicholas J Sibrava; Christina L Boisseau; Maria C Mancebo; Jane L Eisen; Steven A Rasmussen
Journal:  Depress Anxiety       Date:  2011-08-04       Impact factor: 6.505

8.  The impact of symptom dimensions on outcome for exposure and ritual prevention therapy in obsessive-compulsive disorder.

Authors:  Monnica T Williams; Samantha G Farris; Eric N Turkheimer; Martin E Franklin; H Blair Simpson; Michael Liebowitz; Edna B Foa
Journal:  J Anxiety Disord       Date:  2014-06-14

9.  Anatomic alterations across amygdala subnuclei in medication-free patients with obsessive-compulsive disorder.

Authors:  Lianqing Zhang; Xinyu Hu; Lu Lu; Bin Li; Xiaoxiao Hu; Xuan Bu; Hailong Li; Shi Tang; Yingxue Gao; Yanchun Yang; John A Sweeney; Qiyong Gong; Xiaoqi Huang
Journal:  J Psychiatry Neurosci       Date:  2020-09-01       Impact factor: 6.186

Review 10.  Symptom dimensions in obsessive-compulsive disorder: phenomenology and treatment outcomes with exposure and ritual prevention.

Authors:  Monnica T Williams; Beth Mugno; Martin Franklin; Sonya Faber
Journal:  Psychopathology       Date:  2013-04-20       Impact factor: 1.944

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