Literature DB >> 20133040

Cavitation properties of block copolymer stabilized phase-shift nanoemulsions used as drug carriers.

Natalya Rapoport1, Douglas A Christensen, Anne M Kennedy, Kweon-Ho Nam.   

Abstract

Cavitation properties of block copolymer stabilized perfluoropentane nanoemulsions have been investigated. The nanoemulsions were stabilized by two biodegradable amphiphilic block copolymers differing in the structure of the hydrophobic block, poly(ethylene oxide)-co-poly(L-lactide) (PEG-PLLA) and poly(ethylene oxide)-co-polycaprolactone (PEG-PCL). Cavitation parameters were measured in liquid emulsions and gels as a function of ultrasound pressure for unfocused or focused 1-MHz ultrasound. Acoustic droplet vaporization preceded generation of acoustic cavitation in liquid matrices and gels. Both stable and inertial cavitation was observed for focused ultrasound while only stable cavitation was observed for unfocused ultrasound. Copyright 2010 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

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Year:  2010        PMID： 20133040      PMCID： PMC2826577          DOI： 10.1016/j.ultrasmedbio.2009.11.009

Source DB:  PubMed          Journal:  Ultrasound Med Biol        ISSN： 0301-5629            Impact factor:   2.998


  36 in total

1.  Thresholds for inertial cavitation in albunex suspensions under pulsed ultrasound conditions.

Authors:  P P Chang; W S Chen; P D Mourad; S L Poliachik; L A Crum
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2001-01       Impact factor: 2.725

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Authors:  C K Holland; R E Apfel
Journal:  J Acoust Soc Am       Date:  1990-11       Impact factor: 1.840

3.  Acoustic droplet vaporization threshold: effects of pulse duration and contrast agent.

Authors:  Andrea H Lo; Oliver D Kripfgans; Paul L Carson; Edward D Rothman; J Brian Fowlkes
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2007-05       Impact factor: 2.725

4.  Driving delivery vehicles with ultrasound.

Authors:  Katherine W Ferrara
Journal:  Adv Drug Deliv Rev       Date:  2008-03-30       Impact factor: 15.470

5.  Direct in vivo visualization of intravascular destruction of microbubbles by ultrasound and its local effects on tissue.

Authors:  D M Skyba; R J Price; A Z Linka; T C Skalak; S Kaul
Journal:  Circulation       Date:  1998-07-28       Impact factor: 29.690

Review 6.  Exploiting the enhanced permeability and retention effect for tumor targeting.

Authors:  Arun K Iyer; Greish Khaled; Jun Fang; Hiroshi Maeda
Journal:  Drug Discov Today       Date:  2006-09       Impact factor: 7.851

7.  Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption.

Authors:  Manabu Kinoshita; Nathan McDannold; Ferenc A Jolesz; Kullervo Hynynen
Journal:  Proc Natl Acad Sci U S A       Date:  2006-07-25       Impact factor: 11.205

Review 8.  Therapeutic applications of lipid-coated microbubbles.

Authors:  Evan C Unger; Thomas Porter; William Culp; Rachel Labell; Terry Matsunaga; Reena Zutshi
Journal:  Adv Drug Deliv Rev       Date:  2004-05-07       Impact factor: 15.470

9.  Drug-loaded nano/microbubbles for combining ultrasonography and targeted chemotherapy.

Authors:  Zhonggao Gao; Anne M Kennedy; Douglas A Christensen; Natalya Y Rapoport
Journal:  Ultrasonics       Date:  2007-11-19       Impact factor: 2.890

10.  Lipid-shelled vehicles: engineering for ultrasound molecular imaging and drug delivery.

Authors:  Katherine W Ferrara; Mark A Borden; Hua Zhang
Journal:  Acc Chem Res       Date:  2009-07-21       Impact factor: 22.384
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  22 in total

1.  Ultrasound-mediated tumor imaging and nanotherapy using drug loaded, block copolymer stabilized perfluorocarbon nanoemulsions.

Authors:  Natalya Rapoport; Kweon-Ho Nam; Roohi Gupta; Zhongao Gao; Praveena Mohan; Allison Payne; Nick Todd; Xin Liu; Taeho Kim; Jill Shea; Courtney Scaife; Dennis L Parker; Eun-Kee Jeong; Anne M Kennedy
Journal:  J Control Release       Date:  2011-01-26       Impact factor: 9.776

2.  High-speed, clinical-scale microfluidic generation of stable phase-change droplets for gas embolotherapy.

Authors:  David Bardin; Thomas D Martz; Paul S Sheeran; Roger Shih; Paul A Dayton; Abraham P Lee
Journal:  Lab Chip       Date:  2011-10-20       Impact factor: 6.799

3.  Combined passive detection and ultrafast active imaging of cavitation events induced by short pulses of high-intensity ultrasound.

Authors:  Jérôme Gateau; Jean-François Aubry; Mathieu Pernot; Mathias Fink; Mickaël Tanter
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2011-03       Impact factor: 2.725

4.  Phase transitions of nanoemulsions using ultrasound: experimental observations.

Authors:  Ram Singh; Ghaleb A Husseini; William G Pitt
Journal:  Ultrason Sonochem       Date:  2012-03-01       Impact factor: 7.491

Review 5.  Phase-shift, stimuli-responsive perfluorocarbon nanodroplets for drug delivery to cancer.

Authors:  Natalya Rapoport
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2012-06-22

Review 6.  Phase-shift, stimuli-responsive drug carriers for targeted delivery.

Authors:  Brian E O'Neill; Natalya Rapoport
Journal:  Ther Deliv       Date:  2011-09

7.  Precision manufacture of phase-change perfluorocarbon droplets using microfluidics.

Authors:  Thomas D Martz; Paul S Sheeran; David Bardin; Abraham P Lee; Paul A Dayton
Journal:  Ultrasound Med Biol       Date:  2011-10-02       Impact factor: 2.998

8.  Multiple-Exposure Drug Release from Stable Nanodroplets by High-Intensity Focused Ultrasound for a Potential Degenerative Disc Disease Treatment.

Authors:  Khoi Nguyen; Hsuan-Yeh Pan; Kevin Haworth; Eric Mahoney; Karla P Mercado-Shekhar; Chia-Ying Lin; Zhe Zhang; Yoonjee C Park
Journal:  Ultrasound Med Biol       Date:  2018-10-26       Impact factor: 2.998

9.  Indocyanine green-loaded photoacoustic nanodroplets: dual contrast nanoconstructs for enhanced photoacoustic and ultrasound imaging.

Authors:  Alexander Hannah; Geoffrey Luke; Katheryne Wilson; Kimberly Homan; Stanislav Emelianov
Journal:  ACS Nano       Date:  2013-12-18       Impact factor: 15.881

10.  Effect of ultrasound on the permeability of vascular wall to nano-emulsion droplets.

Authors:  Dhaval Thakkar; Roohi Gupta; Kenneth Monson; Natalya Rapoport
Journal:  Ultrasound Med Biol       Date:  2013-07-09       Impact factor: 2.998
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