| Literature DB >> 22730185 |
Abstract
This review focuses on phase-shift perfluorocarbon nanoemulsions whose action depends on an ultrasound-triggered phase shift from a liquid to gas state. For drug-loaded perfluorocarbon nanoemulsions, microbubbles are formed under the action of tumor-directed ultrasound and drug is released locally into tumor volume in this process. This review covers in detail mechanisms involved in the droplet-to-bubble transition as well as mechanisms of ultrasound-mediated drug delivery.Entities:
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Year: 2012 PMID: 22730185 PMCID: PMC3482424 DOI: 10.1002/wnan.1176
Source DB: PubMed Journal: Wiley Interdiscip Rev Nanomed Nanobiotechnol ISSN: 1939-0041