Literature DB >> 22059114

Phase-shift, stimuli-responsive drug carriers for targeted delivery.

Brian E O'Neill1, Natalya Rapoport.   

Abstract

The intersection of particles and directed energy is a rich source of novel and useful technology that is only recently being realized for medicine. One of the most promising applications is directed drug delivery. This review focuses on phase-shift nanoparticles (that is, particles of submicron size) as well as micron-scale particles whose action depends on an external-energy triggered, first-order phase shift from a liquid to gas state of either the particle itself or of the surrounding medium. These particles have tremendous potential for actively disrupting their environment for altering transport properties and unloading drugs. This review covers in detail ultrasound and laser-activated phase-shift nano- and micro-particles and their use in drug delivery. Phase-shift based drug-delivery mechanisms and competing technologies are discussed.

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Year:  2011        PMID： 22059114      PMCID： PMC3207214          DOI： 10.4155/tde.11.81

Source DB:  PubMed          Journal:  Ther Deliv        ISSN： 2041-5990


  224 in total

1.  Acoustic droplet vaporization threshold: effects of pulse duration and contrast agent.

Authors:  Andrea H Lo; Oliver D Kripfgans; Paul L Carson; Edward D Rothman; J Brian Fowlkes
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2007-05       Impact factor: 2.725

2.  Optical excitation and detection of vapor bubbles around plasmonic nanoparticles.

Authors:  Dmitri Lapotko
Journal:  Opt Express       Date:  2009-02-16       Impact factor: 3.894

Review 3.  Nanoparticle-based theranostic agents.

Authors:  Jin Xie; Seulki Lee; Xiaoyuan Chen
Journal:  Adv Drug Deliv Rev       Date:  2010-08-04       Impact factor: 15.470

4.  Pulsed-high intensity focused ultrasound enhanced tPA mediated thrombolysis in a novel in vivo clot model, a pilot study.

Authors:  Michael J Stone; Victor Frenkel; Sergio Dromi; Peter Thomas; Ryan P Lewis; King C P Li; McDonald Horne; Bradford J Wood
Journal:  Thromb Res       Date:  2007-05-04       Impact factor: 3.944

5.  Drug-loaded nano/microbubbles for combining ultrasonography and targeted chemotherapy.

Authors:  Zhonggao Gao; Anne M Kennedy; Douglas A Christensen; Natalya Y Rapoport
Journal:  Ultrasonics       Date:  2007-11-19       Impact factor: 2.890

6.  Ultrasonic microbubble destruction stimulates therapeutic arteriogenesis via the CD18-dependent recruitment of bone marrow-derived cells.

Authors:  John C Chappell; Ji Song; Alexander L Klibanov; Richard J Price
Journal:  Arterioscler Thromb Vasc Biol       Date:  2008-04-10       Impact factor: 8.311

7.  Laser ablation of liver metastases from colorectal cancer with MR thermometry: 5-year survival.

Authors:  Ralf Puls; Soenke Langner; Christian Rosenberg; Katrin Hegenscheid; Jens Peter Kuehn; Kai Noeckler; Norbert Hosten
Journal:  J Vasc Interv Radiol       Date:  2008-12-24       Impact factor: 3.464

8.  Fibrinogen adsorption by PS latex particles coated with various amounts of a PEO/PPO/PEO triblock copolymer.

Authors:  M Bohner; T A Ring; Natalya Rapoport; K D Caldwell
Journal:  J Biomater Sci Polym Ed       Date:  2002       Impact factor: 3.517

9.  Acoustically active perfluorocarbon nanoemulsions as drug delivery carriers for camptothecin: drug release and cytotoxicity against cancer cells.

Authors:  Jia-You Fang; Chi-Feng Hung; Shu-Chiou Hua; Tsong-Long Hwang
Journal:  Ultrasonics       Date:  2008-05-07       Impact factor: 2.890

10.  Ultrasound and microbubble-targeted delivery of macromolecules is regulated by induction of endocytosis and pore formation.

Authors:  Bernadet D M Meijering; Lynda J M Juffermans; Annemieke van Wamel; Rob H Henning; Inge S Zuhorn; Marcia Emmer; Amanda M G Versteilen; Walter J Paulus; Wiek H van Gilst; Klazina Kooiman; Nico de Jong; René J P Musters; Leo E Deelman; Otto Kamp
Journal:  Circ Res       Date:  2009-01-22       Impact factor: 17.367
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  12 in total

Review 1.  Targeted polymeric therapeutic nanoparticles: design, development and clinical translation.

Authors:  Nazila Kamaly; Zeyu Xiao; Pedro M Valencia; Aleksandar F Radovic-Moreno; Omid C Farokhzad
Journal:  Chem Soc Rev       Date:  2012-03-05       Impact factor: 54.564

Review 2.  Extracellularly activatable nanocarriers for drug delivery to tumors.

Authors:  Sara A Abouelmagd; Hyesun Hyun; Yoon Yeo
Journal:  Expert Opin Drug Deliv       Date:  2014-06-20       Impact factor: 6.648

3.  Experimental techniques for imaging and measuring transient vapor nanobubbles.

Authors:  E Y Lukianova-Hleb; D O Lapotko
Journal:  Appl Phys Lett       Date:  2012-12-26       Impact factor: 3.791

4.  Microfluidic generation of acoustically active nanodroplets.

Authors:  Thomas D Martz; David Bardin; Paul S Sheeran; Abraham P Lee; Paul A Dayton
Journal:  Small       Date:  2012-03-29       Impact factor: 13.281

5.  Multiple-Exposure Drug Release from Stable Nanodroplets by High-Intensity Focused Ultrasound for a Potential Degenerative Disc Disease Treatment.

Authors:  Khoi Nguyen; Hsuan-Yeh Pan; Kevin Haworth; Eric Mahoney; Karla P Mercado-Shekhar; Chia-Ying Lin; Zhe Zhang; Yoonjee C Park
Journal:  Ultrasound Med Biol       Date:  2018-10-26       Impact factor: 2.998

Review 6.  Current status and prospects for microbubbles in ultrasound theranostics.

Authors:  K Heath Martin; Paul A Dayton
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2013-03-15

7.  On-demand intracellular amplification of chemoradiation with cancer-specific plasmonic nanobubbles.

Authors:  Xiaoyang Ren; Rupa R Sawant; Ekaterina Y Lukianova-Hleb; Xiangwei Wu; Vladimir P Torchilin; Dmitri O Lapotko
Journal:  Nat Med       Date:  2014-06-01       Impact factor: 53.440

8.  Ultrasound-triggered phase transition sensitive magnetic fluorescent nanodroplets as a multimodal imaging contrast agent in rat and mouse model.

Authors:  Xin Cheng; Huan Li; Yunchao Chen; Binhua Luo; Xuhan Liu; Wei Liu; Haibo Xu; Xiangliang Yang
Journal:  PLoS One       Date:  2013-12-31       Impact factor: 3.240

Review 9.  Acoustic droplet vaporization in biology and medicine.

Authors:  Chung-Yin Lin; William G Pitt
Journal:  Biomed Res Int       Date:  2013-11-20       Impact factor: 3.411

Review 10.  Improving the performance of phase-change perfluorocarbon droplets for medical ultrasonography: current progress, challenges, and prospects.

Authors:  Paul S Sheeran; Paul A Dayton
Journal:  Scientifica (Cairo)       Date:  2014-06-01
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