| Literature DB >> 20131834 |
Partha Ghosh1, Xiaochao Yang, Rochelle Arvizo, Zheng-Jiang Zhu, Sarit S Agasti, Zhihong Mo, Vincent M Rotello.
Abstract
Gold nanoparticles were coated with a short peptide to promote intracellular delivery of membrane-impermeable proteins. Through microscopy and enzyme assays, we demonstrated the particles were able to transport functional enzymes into a variety of cell lines. Significantly, the transported proteins were able to escape from endosomes. Moreover, these particles showed no apparent cytotoxicity.Entities:
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Year: 2010 PMID： 20131834 PMCID： PMC2830715 DOI： 10.1021/ja907887z
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419