Literature DB >> 21671432

Beauty is skin deep: a surface monolayer perspective on nanoparticle interactions with cells and bio-macromolecules.

Krishnendu Saha1, Avinash Bajaj, Bradley Duncan, Vincent M Rotello.   

Abstract

Surface recognition of biosystems is a critical component in the development of novel biosensors and delivery vehicles, and for the therapeutic regulation of biological processes. Monolayer-protected nanoparticles present a highly versatile scaffold for selective interaction with bio-macromolecules and cells. Through the engineering of the monolayer surface, nanoparticles can be tailored for surface recognition of biomolecules and cells. This review highlights recent progress in nanoparticle-bio-macromolecule/cellular interactions, emphasizing the effect of the surface monolayer structure on the interactions with proteins, DNA, and cell surfaces. The extension of these tailored interactions to hybrid nanomaterials, biosensing platforms, and delivery vehicles is also discussed.
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2011        PMID： 21671432      PMCID： PMC3516997          DOI： 10.1002/smll.201100478

Source DB:  PubMed          Journal:  Small        ISSN： 1613-6810            Impact factor:   13.281


  187 in total

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3.  Controlled spacing of cationic gold nanoparticles by nanocrown RNA.

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Review 4.  Principles of protein-protein interactions: what are the preferred ways for proteins to interact?

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Review 5.  Protein- and peptide-directed syntheses of inorganic materials.

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Journal:  Chem Rev       Date:  2008-10-31       Impact factor: 60.622

6.  Nanostructured materials designed for cell binding and transduction.

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Journal:  Biomacromolecules       Date:  2001       Impact factor: 6.988

7.  A nonviral DNA delivery system based on surface modified silica-nanoparticles can efficiently transfect cells in vitro.

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8.  The influence of surface functionalization on the enhanced internalization of magnetic nanoparticles in cancer cells.

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9.  Structure-activity investigation on the gene transfection properties of cardiolipin mimicking gemini lipid analogues.

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Review 10.  Nanoparticles for detection and diagnosis.

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  28 in total

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Review 3.  Surface functionalization of nanoparticles for nanomedicine.

Authors:  Rubul Mout; Daniel F Moyano; Subinoy Rana; Vincent M Rotello
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4.  Surface decorated gold nanoparticles by linear and cyclic peptides as molecular transporters.

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Journal:  Mol Pharm       Date:  2013-07-25       Impact factor: 4.939

5.  Surface functionality of nanoparticles determines cellular uptake mechanisms in mammalian cells.

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6.  The Gold Nanorod-Biology Interface: From Proteins to Cells to Tissue.

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7.  The Interplay of Size and Surface Functionality on the Cellular Uptake of Sub-10 nm Gold Nanoparticles.

Authors:  Ying Jiang; Shuaidong Huo; Tsukasa Mizuhara; Riddha Das; Yi-Wei Lee; Singyuk Hou; Daniel F Moyano; Bradley Duncan; Xing-Jie Liang; Vincent M Rotello
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8.  Control of nanoparticle penetration into biofilms through surface design.

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Review 9.  Nanomedicines for renal disease: current status and future applications.

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10.  Using the Power of Organic Synthesis for Engineering the Interactions of Nanoparticles with Biological Systems.

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