Literature DB >> 20130565

Deconstructing the drug development process: the new face of innovation.

K I Kaitin1.   

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Year:  2010        PMID： 20130565      PMCID： PMC2953249          DOI： 10.1038/clpt.2009.293

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


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  5 in total

1.  Risks in new drug development: approval success rates for investigational drugs.

Authors:  J A Dimasi
Journal:  Clin Pharmacol Ther       Date:  2001-05       Impact factor: 6.875

2.  Returns on research and development for 1990s new drug introductions.

Authors:  Henry Grabowski; John Vernon; Joseph A DiMasi
Journal:  Pharmacoeconomics       Date:  2002       Impact factor: 4.981

3.  Assessing the impact of protocol design changes on clinical trial performance.

Authors:  Kenneth A Getz; Julia Wenger; Rafael A Campo; Edward S Seguine; Kenneth I Kaitin
Journal:  Am J Ther       Date:  2008 Sep-Oct       Impact factor: 2.688

Review 4.  Trends in risks associated with new drug development: success rates for investigational drugs.

Authors:  J A DiMasi; L Feldman; A Seckler; A Wilson
Journal:  Clin Pharmacol Ther       Date:  2010-02-03       Impact factor: 6.875

5.  Translational medicine: an engine of change for bringing new technology to community health.

Authors:  Christopher-Paul Milne; Kenneth I Kaitin
Journal:  Sci Transl Med       Date:  2009-11-04       Impact factor: 17.956
  5 in total
  67 in total

Review 1.  Prediction of exposure-response relationships to support first-in-human study design.

Authors:  John P Gibbs
Journal:  AAPS J       Date:  2010-10-22       Impact factor: 4.009

Review 2.  Lessons from the past and charting the future of marine natural products drug discovery and chemical biology.

Authors:  William H Gerwick; Bradley S Moore
Journal:  Chem Biol       Date:  2012-01-27

3.  Translating Drugs From Animals to Humans: Do We Need to Prove Efficacy?

Authors:  Gary D Novack
Journal:  Transl Vis Sci Technol       Date:  2013-09-12       Impact factor: 3.283

4.  Role of Academic Drug Discovery in the Quest for New CNS Therapeutics.

Authors:  Brian H Yokley; Matthew Hartman; Barbara S Slusher
Journal:  ACS Chem Neurosci       Date:  2017-02-14       Impact factor: 4.418

5.  Cross-site strain comparison of pharmacological deficits in the touchscreen visual discrimination test.

Authors:  Eric G Mohler; Zhiyong Ding; Lynne E Rueter; Douglas Chapin; Damon Young; Rouba Kozak
Journal:  Psychopharmacology (Berl)       Date:  2015-07-17       Impact factor: 4.530

Review 6.  Trends in the exploitation of novel drug targets.

Authors:  Mathias Rask-Andersen; Markus Sällman Almén; Helgi B Schiöth
Journal:  Nat Rev Drug Discov       Date:  2011-08-01       Impact factor: 84.694

Review 7.  GUCY2C ligand replacement to prevent colorectal cancer.

Authors:  Erik S Blomain; Amanda M Pattison; Scott A Waldman
Journal:  Cancer Biol Ther       Date:  2016-04-22       Impact factor: 4.742

Review 8.  Insights into Computational Drug Repurposing for Neurodegenerative Disease.

Authors:  Manish D Paranjpe; Alice Taubes; Marina Sirota
Journal:  Trends Pharmacol Sci       Date:  2019-07-17       Impact factor: 14.819

Review 9.  Translating biomarkers to clinical practice.

Authors:  R H Perlis
Journal:  Mol Psychiatry       Date:  2011-06-28       Impact factor: 15.992

Review 10.  In silico methods for drug repurposing and pharmacology.

Authors:  Rachel A Hodos; Brian A Kidd; Khader Shameer; Ben P Readhead; Joel T Dudley
Journal:  Wiley Interdiscip Rev Syst Biol Med       Date:  2016-04-15
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