Literature DB >> 24078898

Translating Drugs From Animals to Humans: Do We Need to Prove Efficacy?

Gary D Novack1.   

Abstract

Entities:  

Keywords:  drug development; preclinical; regulatory

Year:  2013        PMID： 24078898      PMCID： PMC3783258          DOI： 10.1167/tvst.2.6.1

Source DB:  PubMed          Journal:  Transl Vis Sci Technol        ISSN： 2164-2591            Impact factor:   3.283


× No keyword cloud information.
  25 in total

1.  Report of the TFOS/ARVO Symposium on global treatments for dry eye disease: an unmet need.

Authors:  David A Sullivan; Katherine M Hammitt; Debra A Schaumberg; Benjamin D Sullivan; Carolyn G Begley; Per Gjorstrup; Jean-Sébastien Garrigue; Masatsugu Nakamura; Yann Quentric; Stefano Barabino; Michelle Dalton; Gary D Novack
Journal:  Ocul Surf       Date:  2012-02-08       Impact factor: 5.033

2.  Effect of pilocarpine 4% in combination with latanoprost 0.005% or 8-iso prostaglandin E2 0.1% on intraocular pressure in laser-induced glaucomatous monkey eyes.

Authors:  J B Serle; R F Wang; T W Mittag; F Shen; S M Podos
Journal:  J Glaucoma       Date:  2001-06       Impact factor: 2.503

3.  The pharmacologic assessment of a novel lymphocyte function-associated antigen-1 antagonist (SAR 1118) for the treatment of keratoconjunctivitis sicca in dogs.

Authors:  Christopher J Murphy; Ellison Bentley; Paul E Miller; Kim McIntyre; Gary Leatherberry; Richard Dubielzig; Elizabeth Giuliano; Cecil P Moore; Thomas E Phillips; Peter B Smith; Elizabeth Prescott; Jacqueline M Miller; Peter Thomas; Randall Scagliotti; Doug Esson; Tom Gadek; Charles A O'Neill
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-05-16       Impact factor: 4.799

4.  Alternative splice variants of the USH3A gene Clarin 1 (CLRN1).

Authors:  Hanna Västinsalo; Reetta Jalkanen; Astra Dinculescu; Juha Isosomppi; Scott Geller; John G Flannery; William W Hauswirth; Eeva-Marja Sankila
Journal:  Eur J Hum Genet       Date:  2010-08-18       Impact factor: 4.246

5.  Spontaneous canine keratoconjunctivitis sicca. A useful model for human keratoconjunctivitis sicca: treatment with cyclosporine eye drops.

Authors:  R L Kaswan; M A Salisbury; D A Ward
Journal:  Arch Ophthalmol       Date:  1989-08

6.  Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, I: Functional measures.

Authors:  William A Hare; Elizabeth WoldeMussie; Ronald K Lai; Hau Ton; Guadalupe Ruiz; Teresa Chun; Larry Wheeler
Journal:  Invest Ophthalmol Vis Sci       Date:  2004-08       Impact factor: 4.799

7.  Cone structure in patients with usher syndrome type III and mutations in the Clarin 1 gene.

Authors:  Kavitha Ratnam; Hanna Västinsalo; Austin Roorda; Eeva-Marja K Sankila; Jacque L Duncan
Journal:  JAMA Ophthalmol       Date:  2013-01       Impact factor: 7.389

8.  The kinase inhibitor PKC412 suppresses epiretinal membrane formation and retinal detachment in mice with proliferative retinopathies.

Authors:  Yoshitsugu Saishin; Yumiko Saishin; Kyoichi Takahashi; Man-Seong Seo; Michele Melia; Peter A Campochiaro
Journal:  Invest Ophthalmol Vis Sci       Date:  2003-08       Impact factor: 4.799

9.  Effects of intraocular ranibizumab and bevacizumab in transgenic mice expressing human vascular endothelial growth factor.

Authors:  Katsuaki Miki; Akiko Miki; Masato Matsuoka; Daisuke Muramatsu; Sean F Hackett; Peter A Campochiaro
Journal:  Ophthalmology       Date:  2009-07-29       Impact factor: 12.079

10.  Localization of Usher 1 proteins to the photoreceptor calyceal processes, which are absent from mice.

Authors:  Iman Sahly; Eric Dufour; Cataldo Schietroma; Vincent Michel; Amel Bahloul; Isabelle Perfettini; Elise Pepermans; Amrit Estivalet; Diane Carette; Asadollah Aghaie; Inga Ebermann; Andrea Lelli; Maria Iribarne; Jean-Pierre Hardelin; Dominique Weil; José-Alain Sahel; Aziz El-Amraoui; Christine Petit
Journal:  J Cell Biol       Date:  2012-10-08       Impact factor: 10.539
View more
  4 in total

Review 1.  Improving the predictive value of interventional animal models data.

Authors:  Caroline J Zeiss
Journal:  Drug Discov Today       Date:  2014-11-04       Impact factor: 7.851

2.  Established patterns of animal study design undermine translation of disease-modifying therapies for Parkinson's disease.

Authors:  Caroline J Zeiss; Heather G Allore; Amanda P Beck
Journal:  PLoS One       Date:  2017-02-09       Impact factor: 3.240

3.  Comparing The Efficacy Of An Anti-Human VEGF-A Neutralizing Antibody Versus Bevacizumab On A Laser-Induced Choroidal Neovascularization (CNV) Rhesus Monkey Model.

Authors:  Oscar Olvera-Montaño; Leopoldo Baiza-Duran; Juan D Quintana-Hau; Mayra G Quiñonez-Alvarado; Wen Zeng; Li Gong; Patricia Muñoz-Villegas
Journal:  Drug Des Devel Ther       Date:  2019-11-04       Impact factor: 4.162

4.  Menagerie: A text-mining tool to support animal-human translation in neurodegeneration research.

Authors:  Caroline J Zeiss; Dongwook Shin; Brent Vander Wyk; Amanda P Beck; Natalie Zatz; Charles A Sneiderman; Halil Kilicoglu
Journal:  PLoS One       Date:  2019-12-17       Impact factor: 3.240
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.