Literature DB >> 20104246

Inborn variation in metabolism.

Vamsi K Mootha, Joel N Hirschhorn.   

Abstract

Advances in analytical biochemistry have recently made it possible to obtain global snapshots of metabolism. A new study couples such technology with genome-wide genetic analysis to explore inherited variation in human metabolism.

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Mesh：

Year:  2010        PMID： 20104246     DOI： 10.1038/ng0210-97

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  13 in total

1.  Functional variants of OCTN cation transporter genes are associated with Crohn disease.

Authors:  Vanya D Peltekova; Richard F Wintle; Laurence A Rubin; Christopher I Amos; Qiqing Huang; Xiangjun Gu; Bill Newman; Mark Van Oene; David Cescon; Gordon Greenberg; Anne M Griffiths; Peter H St George-Hyslop; Katherine A Siminovitch
Journal:  Nat Genet       Date:  2004-04-11       Impact factor: 38.330

2.  The genetics of plant metabolism.

Authors:  Joost J B Keurentjes; Jingyuan Fu; C H Ric de Vos; Arjen Lommen; Robert D Hall; Raoul J Bino; Linus H W van der Plas; Ritsert C Jansen; Dick Vreugdenhil; Maarten Koornneef
Journal:  Nat Genet       Date:  2006-06-04       Impact factor: 38.330

3.  Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies.

Authors:  Andrew D Skol; Laura J Scott; Gonçalo R Abecasis; Michael Boehnke
Journal:  Nat Genet       Date:  2006-01-15       Impact factor: 38.330

4.  Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.

Authors:  Karen L Mohlke; Michael Boehnke; Gonçalo R Abecasis
Journal:  Hum Mol Genet       Date:  2008-10-15       Impact factor: 6.150

5.  Refined genomic localization and ethnic differences observed for the IBD5 association with Crohn's disease.

Authors:  Mark S Silverberg; Richard H Duerr; Steven R Brant; Gillian Bromfield; Lisa W Datta; Niraj Jani; Sunanda V Kane; Jerome I Rotter; L Philip Schumm; A Hillary Steinhart; Kent D Taylor; Huiying Yang; Judy H Cho; John D Rioux; Mark J Daly
Journal:  Eur J Hum Genet       Date:  2007-01-10       Impact factor: 4.246

6.  The frequency of short-chain acyl-CoA dehydrogenase gene variants in the US population and correlation with the C(4)-acylcarnitine concentration in newborn blood spots.

Authors:  Narasimhan Nagan; Kent E Kruckeberg; Angela L Tauscher; Karen Snow Bailey; Piero Rinaldo; Dietrich Matern
Journal:  Mol Genet Metab       Date:  2003-04       Impact factor: 4.797

7.  A genome-wide perspective of genetic variation in human metabolism.

Authors:  Thomas Illig; Christian Gieger; Guangju Zhai; Werner Römisch-Margl; Rui Wang-Sattler; Cornelia Prehn; Elisabeth Altmaier; Gabi Kastenmüller; Bernet S Kato; Hans-Werner Mewes; Thomas Meitinger; Martin Hrabé de Angelis; Florian Kronenberg; Nicole Soranzo; H-Erich Wichmann; Tim D Spector; Jerzy Adamski; Karsten Suhre
Journal:  Nat Genet       Date:  2009-12-27       Impact factor: 38.330

8.  Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum.

Authors:  Christian Gieger; Ludwig Geistlinger; Elisabeth Altmaier; Martin Hrabé de Angelis; Florian Kronenberg; Thomas Meitinger; Hans-Werner Mewes; H-Erich Wichmann; Klaus M Weinberger; Jerzy Adamski; Thomas Illig; Karsten Suhre
Journal:  PLoS Genet       Date:  2008-11-28       Impact factor: 5.917

9.  Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling.

Authors:  Christine T Ferrara; Ping Wang; Elias Chaibub Neto; Robert D Stevens; James R Bain; Brett R Wenner; Olga R Ilkayeva; Mark P Keller; Daniel A Blasiole; Christina Kendziorski; Brian S Yandell; Christopher B Newgard; Alan D Attie
Journal:  PLoS Genet       Date:  2008-03-14       Impact factor: 5.917

10.  Common variants at 30 loci contribute to polygenic dyslipidemia.

Authors:  Sekar Kathiresan; Cristen J Willer; Gina M Peloso; Serkalem Demissie; Kiran Musunuru; Eric E Schadt; Lee Kaplan; Derrick Bennett; Yun Li; Toshiko Tanaka; Benjamin F Voight; Lori L Bonnycastle; Anne U Jackson; Gabriel Crawford; Aarti Surti; Candace Guiducci; Noel P Burtt; Sarah Parish; Robert Clarke; Diana Zelenika; Kari A Kubalanza; Mario A Morken; Laura J Scott; Heather M Stringham; Pilar Galan; Amy J Swift; Johanna Kuusisto; Richard N Bergman; Jouko Sundvall; Markku Laakso; Luigi Ferrucci; Paul Scheet; Serena Sanna; Manuela Uda; Qiong Yang; Kathryn L Lunetta; Josée Dupuis; Paul I W de Bakker; Christopher J O'Donnell; John C Chambers; Jaspal S Kooner; Serge Hercberg; Pierre Meneton; Edward G Lakatta; Angelo Scuteri; David Schlessinger; Jaakko Tuomilehto; Francis S Collins; Leif Groop; David Altshuler; Rory Collins; G Mark Lathrop; Olle Melander; Veikko Salomaa; Leena Peltonen; Marju Orho-Melander; Jose M Ordovas; Michael Boehnke; Gonçalo R Abecasis; Karen L Mohlke; L Adrienne Cupples
Journal:  Nat Genet       Date:  2008-12-07       Impact factor: 38.330
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  9 in total

1.  Human metabolic individuality in biomedical and pharmaceutical research.

Authors:  So-Youn Shin; Ann-Kristin Petersen; Nicole Soranzo; Christian Gieger; Karsten Suhre; Robert P Mohney; David Meredith; Brigitte Wägele; Elisabeth Altmaier; Panos Deloukas; Jeanette Erdmann; Elin Grundberg; Christopher J Hammond; Martin Hrabé de Angelis; Gabi Kastenmüller; Anna Köttgen; Florian Kronenberg; Massimo Mangino; Christa Meisinger; Thomas Meitinger; Hans-Werner Mewes; Michael V Milburn; Cornelia Prehn; Johannes Raffler; Janina S Ried; Werner Römisch-Margl; Nilesh J Samani; Kerrin S Small; H-Erich Wichmann; Guangju Zhai; Thomas Illig; Tim D Spector; Jerzy Adamski
Journal:  Nature       Date:  2011-08-31       Impact factor: 49.962

Review 2.  Genetic variation in metabolic phenotypes: study designs and applications.

Authors:  Karsten Suhre; Christian Gieger
Journal:  Nat Rev Genet       Date:  2012-10-03       Impact factor: 53.242

Review 3.  Omics technologies and the study of human ageing.

Authors:  Ana M Valdes; Daniel Glass; Tim D Spector
Journal:  Nat Rev Genet       Date:  2013-08-13       Impact factor: 53.242

4.  13C-isotope-based protocol for prenyl lipid metabolic analysis in zebrafish embryos.

Authors:  Vera Mugoni; Claudio Medana; Massimo M Santoro
Journal:  Nat Protoc       Date:  2013-10-31       Impact factor: 13.491

5.  Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits.

Authors:  Ann-Kristin Petersen; Sonja Zeilinger; Gabi Kastenmüller; Werner Römisch-Margl; Markus Brugger; Annette Peters; Christine Meisinger; Konstantin Strauch; Christian Hengstenberg; Philipp Pagel; Fritz Huber; Robert P Mohney; Harald Grallert; Thomas Illig; Jerzy Adamski; Melanie Waldenberger; Christian Gieger; Karsten Suhre
Journal:  Hum Mol Genet       Date:  2013-09-06       Impact factor: 6.150

6.  Dynamic modelling of an ACADS genotype in fatty acid oxidation - Application of cellular models for the analysis of common genetic variants.

Authors:  Kerstin Matejka; Ferdinand Stückler; Michael Salomon; Regina Ensenauer; Eva Reischl; Lena Hoerburger; Harald Grallert; Gabi Kastenmüller; Annette Peters; Hannelore Daniel; Jan Krumsiek; Fabian J Theis; Hans Hauner; Helmut Laumen
Journal:  PLoS One       Date:  2019-05-23       Impact factor: 3.240

Review 7.  Emerging Insights into the Metabolic Alterations in Aging Using Metabolomics.

Authors:  Sarika Srivastava
Journal:  Metabolites       Date:  2019-12-13

8.  Predicting the impact of diet and enzymopathies on human small intestinal epithelial cells.

Authors:  Swagatika Sahoo; Ines Thiele
Journal:  Hum Mol Genet       Date:  2013-03-13       Impact factor: 6.150

9.  An atlas of genetic influences on human blood metabolites.

Authors:  So-Youn Shin; Eric B Fauman; Ann-Kristin Petersen; Jan Krumsiek; Rita Santos; Jie Huang; Matthias Arnold; Idil Erte; Vincenzo Forgetta; Tsun-Po Yang; Klaudia Walter; Cristina Menni; Lu Chen; Louella Vasquez; Ana M Valdes; Craig L Hyde; Vicky Wang; Daniel Ziemek; Phoebe Roberts; Li Xi; Elin Grundberg; Melanie Waldenberger; J Brent Richards; Robert P Mohney; Michael V Milburn; Sally L John; Jeff Trimmer; Fabian J Theis; John P Overington; Karsten Suhre; M Julia Brosnan; Christian Gieger; Gabi Kastenmüller; Tim D Spector; Nicole Soranzo
Journal:  Nat Genet       Date:  2014-05-11       Impact factor: 38.330
  9 in total

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