Literature DB >> 2007651

Rapid, on-site diagnosis of chlamydial urethritis in men by detection of antigens in urethral swabs and urine.

J Sellors1, J Mahony, D Jang, L Pickard, S Castriciano, S Landis, I Stewart, W Seidelman, I Cunningham, M Chernesky.   

Abstract

First-void urine (FVU) sediments of 240 men were tested for Chlamydia trachomatis antigens by two enzyme immunoassays, TestPack Chlamydia (15 min) and Chlamydiazyme (3.5 h), and the results were compared with urethral swab culture results. The sensitivity and specificity on FVU sediment for TestPack Chlamydia were 76.2% (32 of 42 specimens) and 95.5% (189 of 198 specimens) versus 81.0% (34 of 42 specimens) and 96.5% (191 of 198 specimens) for Chlamydiazyme, respectively. Rapid, on-site detection of chlamydial antigen in male FVU would shorten the infectious period by hastening diagnosis and treatment.

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Year:  1991        PMID： 2007651      PMCID： PMC269779          DOI： 10.1128/jcm.29.2.407-409.1991

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  6 in total

1.  Evaluation of three Chlamydia trachomatis immunoassays with an unbiased, noninvasive clinical sample.

Authors:  I D Paul; E O Caul
Journal:  J Clin Microbiol       Date:  1990-02       Impact factor: 5.948

2.  Non-invasive sampling method for detecting Chlamydia trachomatis.

Authors:  E O Caul; I D Paul; J D Milne; T Crowley
Journal:  Lancet       Date:  1988-11-26       Impact factor: 79.321

3.  TestPack Chlamydia, a new rapid assay for the direct detection of Chlamydia trachomatis.

Authors:  P Coleman; V Varitek; I K Mushahwar; B Marchlewicz; J Safford; J Hansen; G Kurpiewski; T Grier
Journal:  J Clin Microbiol       Date:  1989-12       Impact factor: 5.948

4.  Evaluation of a genus-specific monoclonal antibody in an amplified enzyme-linked immunoassay in the detection of Chlamydia in urine samples from men.

Authors:  A J Jawad; G Manuel; R Matthews; R Wise; J C Clay
Journal:  Sex Transm Dis       Date:  1990 Apr-Jun       Impact factor: 2.830

5.  Detection of Chlamydia trachomatis antigens by enzyme immunoassay and immunofluorescence in genital specimens from symptomatic and asymptomatic men and women.

Authors:  M A Chernesky; J B Mahony; S Castriciano; M Mores; I O Stewart; S J Landis; W Seidelman; E J Sargeant; C Leman
Journal:  J Infect Dis       Date:  1986-07       Impact factor: 5.226

6.  Chlamydia trachomatis infections in the United States. What are they costing us?

Authors:  A E Washington; R E Johnson; L L Sanders
Journal:  JAMA       Date:  1987-04-17       Impact factor: 56.272
  6 in total
  17 in total

1.  Confirmatory polymerase chain reaction testing for Chlamydia trachomatis in first-void urine from asymptomatic and symptomatic men.

Authors:  J B Mahony; K E Luinstra; J W Sellors; D Jang; M A Chernesky
Journal:  J Clin Microbiol       Date:  1992-09       Impact factor: 5.948

2.  The value of non-culture techniques for diagnosis of Chlamydia trachomatis infections: making the best of a bad job.

Authors:  D Taylor-Robinson
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1992-06       Impact factor: 3.267

Review 3.  Laboratory techniques for the diagnosis of chlamydial infections.

Authors:  D Taylor-Robinson; B J Thomas
Journal:  Genitourin Med       Date:  1991-06

4.  Interlaboratory agreement study of a double set of PCR plasmid primers for detection of Chlamydia trachomatis in a variety of genitourinary specimens.

Authors:  J B Mahony; K E Luinstra; J Waner; G McNab; H Hobranzska; D Gregson; J W Sellors; M A Chernesky
Journal:  J Clin Microbiol       Date:  1994-01       Impact factor: 5.948

5.  Impact of reference standard sensitivity on accuracy of rapid antigen detection assays and a leukocyte esterase dipstick for diagnosis of Chlamydia trachomatis infection in first-void urine specimens from men.

Authors:  M Chernesky; D Jang; J Krepel; J Sellors; J Mahony
Journal:  J Clin Microbiol       Date:  1999-09       Impact factor: 5.948

6.  Comparison of plasmid- and chromosome-based polymerase chain reaction assays for detecting Chlamydia trachomatis nucleic acids.

Authors:  J B Mahony; K E Luinstra; J W Sellors; M A Chernesky
Journal:  J Clin Microbiol       Date:  1993-07       Impact factor: 5.948

7.  Periodic health examination, 1996 update: 2. Screening for chlamydial infections. Canadian Task Force on the Periodic Health Examination.

Authors:  H D Davies; E E Wang
Journal:  CMAJ       Date:  1996-06-01       Impact factor: 8.262

8.  Comparison of the Clearview Chlamydia test, Chlamydiazyme, and cell culture for detection of Chlamydia trachomatis in women with a low prevalence of infection.

Authors:  M Skulnick; G W Small; A E Simor; D E Low; H Khosid; S Fraser; R Chua
Journal:  J Clin Microbiol       Date:  1991-09       Impact factor: 5.948

9.  Use of a urine enzyme immunoassay as a diagnostic tool for Chlamydia trachomatis urethritis in men.

Authors:  J R Schwebke; A M Clark; M B Pettinger; P Nsubga; W E Stamm
Journal:  J Clin Microbiol       Date:  1991-11       Impact factor: 5.948

10.  Evaluation of chlamydiazyme enzyme immunoassay for detection of Chlamydia trachomatis in urine specimens from men.

Authors:  J M Ehret; J C Leszcynski; J M Douglas; S L Genova; M A Chernesky; J Moncada; J Schachter
Journal:  J Clin Microbiol       Date:  1993-10       Impact factor: 5.948
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