Literature DB >> 20066104

Morphogen gradient formation.

Ortrud Wartlick1, Anna Kicheva, Marcos González-Gaitán.   

Abstract

How morphogen gradients are formed in target tissues is a key question for understanding the mechanisms of morphological patterning. Here, we review different mechanisms of morphogen gradient formation from theoretical and experimental points of view. First, a simple, comprehensive overview of the underlying biophysical principles of several mechanisms of gradient formation is provided. We then discuss the advantages and limitations of different experimental approaches to gradient formation analysis.

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Year:  2009        PMID： 20066104      PMCID： PMC2773637          DOI： 10.1101/cshperspect.a001255

Source DB:  PubMed          Journal:  Cold Spring Harb Perspect Biol        ISSN： 1943-0264            Impact factor:   10.005


  74 in total

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Authors:  C Tickle; D Summerbell; L Wolpert
Journal:  Nature       Date:  1975-03-20       Impact factor: 49.962

2.  Morphogen gradient formation in a complex environment: an anomalous diffusion model.

Authors:  Gil Hornung; Brian Berkowitz; Naama Barkai
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2005-10-17

Review 3.  Quantitative imaging of the green fluorescent protein (GFP).

Authors:  D W Piston; G H Patterson; S M Knobel
Journal:  Methods Cell Biol       Date:  1999       Impact factor: 1.441

4.  The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner.

Authors:  W Driever; C Nüsslein-Volhard
Journal:  Cell       Date:  1988-07-01       Impact factor: 41.582

5.  Dual roles for patched in sequestering and transducing Hedgehog.

Authors:  Y Chen; G Struhl
Journal:  Cell       Date:  1996-11-01       Impact factor: 41.582

6.  A reaction-diffusion wave on the skin of the marine angelfish Pomacanthus.

Authors:  S Kondo; R Asal
Journal:  Nature       Date:  1995-08-31       Impact factor: 49.962

Review 7.  Seeing is believing: the bicoid morphogen gradient matures.

Authors:  Anne Ephrussi; Daniel St Johnston
Journal:  Cell       Date:  2004-01-23       Impact factor: 41.582

8.  Shape and function of the Bicoid morphogen gradient in dipteran species with different sized embryos.

Authors:  Thomas Gregor; Alistair P McGregor; Eric F Wieschaus
Journal:  Dev Biol       Date:  2008-02-13       Impact factor: 3.582

9.  Direct and long-range action of a DPP morphogen gradient.

Authors:  D Nellen; R Burke; G Struhl; K Basler
Journal:  Cell       Date:  1996-05-03       Impact factor: 41.582

10.  Time-dependent patterning of the mesoderm and endoderm by Nodal signals in zebrafish.

Authors:  Engda G Hagos; Scott T Dougan
Journal:  BMC Dev Biol       Date:  2007-03-28       Impact factor: 1.978
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  104 in total

1.  Uniform auxin triggers the Rho GTPase-dependent formation of interdigitation patterns in pavement cells.

Authors:  Tongda Xu; Shingo Nagawa; Zhenbiao Yang
Journal:  Small GTPases       Date:  2011-07-01

2.  The pattern of nodal morphogen signaling is shaped by co-receptor expression.

Authors:  Nathan D Lord; Adam N Carte; Philip B Abitua; Alexander F Schier
Journal:  Elife       Date:  2021-05-26       Impact factor: 8.140

3.  Physical interpretation of mean local accumulation time of morphogen gradient formation.

Authors:  Alexander M Berezhkovskii; Stanislav Y Shvartsman
Journal:  J Chem Phys       Date:  2011-10-21       Impact factor: 3.488

4.  How long does it take to establish a morphogen gradient?

Authors:  Alexander M Berezhkovskii; Christine Sample; Stanislav Y Shvartsman
Journal:  Biophys J       Date:  2010-10-20       Impact factor: 4.033

5.  Evaluating the Drosophila Bicoid morphogen gradient system through dissecting the noise in transcriptional bursts.

Authors:  Feng He; Jie Ren; Wei Wang; Jun Ma
Journal:  Bioinformatics       Date:  2012-02-02       Impact factor: 6.937

Review 6.  Concise Review: Stem Cell Microenvironment on a Chip: Current Technologies for Tissue Engineering and Stem Cell Biology.

Authors:  DoYeun Park; Jaeho Lim; Joong Yull Park; Sang-Hoon Lee
Journal:  Stem Cells Transl Med       Date:  2015-10-08       Impact factor: 6.940

7.  Kinetics of receptor occupancy during morphogen gradient formation.

Authors:  Alexander M Berezhkovskii; Stanislav Y Shvartsman
Journal:  J Chem Phys       Date:  2013-06-28       Impact factor: 3.488

8.  Mechanism and implications of morphogen shuttling: Lessons learned from dorsal and Cactus in Drosophila.

Authors:  Allison E Schloop; Sophia Carrell-Noel; Jeramey Friedman; Alexander Thomas; Gregory T Reeves
Journal:  Dev Biol       Date:  2020-01-24       Impact factor: 3.582

9.  Local kinetics of morphogen gradients.

Authors:  Peter V Gordon; Christine Sample; Alexander M Berezhkovskii; Cyrill B Muratov; Stanislav Y Shvartsman
Journal:  Proc Natl Acad Sci U S A       Date:  2011-03-28       Impact factor: 11.205

10.  Adaptation of the length scale and amplitude of the Bicoid gradient profile to achieve robust patterning in abnormally large Drosophila melanogaster embryos.

Authors:  David Cheung; Cecelia Miles; Martin Kreitman; Jun Ma
Journal:  Development       Date:  2013-11-27       Impact factor: 6.868
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