Literature DB >> 2002464

Effect of hydroxyl group configuration in hydroxyethylamine dipeptide isosteres on HIV protease inhibition. Evidence for multiple binding modes.

D H Rich1, C Q Sun, J V Vara Prasad, A Pathiasseril, M V Toth, G R Marshall, M Clare, R A Mueller, K Houseman.   

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Year:  1991        PMID： 2002464     DOI： 10.1021/jm00107a049

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  14 in total

1.  Universal peptidomimetics.

Authors:  Eunhwa Ko; Jing Liu; Lisa M Perez; Genliang Lu; Amber Schaefer; Kevin Burgess
Journal:  J Am Chem Soc       Date:  2010-12-23       Impact factor: 15.419

Review 2.  Identification of HIV inhibitors guided by free energy perturbation calculations.

Authors:  Orlando Acevedo; Zandrea Ambrose; Patrick T Flaherty; Hadega Aamer; Prashi Jain; Somisetti V Sambasivarao
Journal:  Curr Pharm Des       Date:  2012       Impact factor: 3.116

Review 3.  Antiviral therapy for human immunodeficiency virus infections.

Authors:  E De Clercq
Journal:  Clin Microbiol Rev       Date:  1995-04       Impact factor: 26.132

4.  Asymmetric Aldol Route to Hydroxyethylamine Isostere: Stereoselective Synthesis of the Core Unit of Saquinavir.

Authors:  Arun K Ghosh; Khaja Azhar Hussain; Steve Fidanze
Journal:  J Org Chem       Date:  1997-08-22       Impact factor: 4.354

5.  Asymmetric dihydroxylation route to a dipeptide isostere of a protease inhibitor: enantioselective synthesis of the core unit of ritonavir.

Authors:  Arun K Ghosh; Dongwoo Shin; Packiarajan Mathivanan
Journal:  Chem Commun (Camb)       Date:  1999       Impact factor: 6.222

6.  STEREOCONTROLLED SYNTHESIS OF HIV-l PROTEASE INHIBITORS WITH C2-AXIS OF SYMMETRY.

Authors:  Arun K Ghosh; Sean P McKee; Wayne J Thompson
Journal:  Tetrahedron Lett       Date:  2001-03-26       Impact factor: 2.415

7.  cis-1-Aminoindan-2-ol in Asymmetric Syntheses.

Authors:  Arun K Ghosh; Steve Fidanze; Chris H Senanayake
Journal:  Synthesis (Stuttg)       Date:  1998-07       Impact factor: 3.157

8.  Predicting relative binding affinities of non-peptide HIV protease inhibitors with free energy perturbation calculations.

Authors:  M A McCarrick; P A Kollman
Journal:  J Comput Aided Mol Des       Date:  1999-03       Impact factor: 3.686

9.  A Facile and Enantiospecific Synthesis of 2(S)- and 2(R)-[1'(S)-Azido-2-phenylethyl]oxirane.

Authors:  Arun K Ghosh; Sean P McKee; Hee Yoon Lee; Wayne J Thompson
Journal:  J Chem Soc Chem Commun       Date:  1992

10.  In vitro isolation and identification of human immunodeficiency virus (HIV) variants with reduced sensitivity to C-2 symmetrical inhibitors of HIV type 1 protease.

Authors:  M J Otto; S Garber; D L Winslow; C D Reid; P Aldrich; P K Jadhav; C E Patterson; C N Hodge; Y S Cheng
Journal:  Proc Natl Acad Sci U S A       Date:  1993-08-15       Impact factor: 11.205
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