Literature DB >> 20008930

Overcoming inhibition in the spindle checkpoint.

Vincent Vanoosthuyse1, Kevin G Hardwick.   

Abstract

Spindle checkpoint silencing is a critical step during mitosis that initiates chromosome segregation, yet surprisingly little is known about its mechanism. Protein phosphatase I (PP1) was shown recently to be a key player in this process, and in this issue of Genes & Deverlopment, Akiyoshi and colleagues (pp. 2887-2899) identify budding yeast Fin1p as a kinetochore-localized regulator of PP1 activity toward checkpoint targets. Here we review recent mechanistic insights and propose a working model for spindle checkpoint silencing.

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Year:  2009        PMID： 20008930      PMCID： PMC2800088          DOI： 10.1101/gad.1882109

Source DB:  PubMed          Journal:  Genes Dev        ISSN： 0890-9369            Impact factor:   11.361


  57 in total

1.  The disappearance of cyclin B at the end of mitosis is regulated spatially in Drosophila cells.

Authors:  J Huang; J W Raff
Journal:  EMBO J       Date:  1999-04-15       Impact factor: 11.598

2.  Phosphorylation of Cdc20 by Bub1 provides a catalytic mechanism for APC/C inhibition by the spindle checkpoint.

Authors:  Zhanyun Tang; Hongjun Shu; Dilhan Oncel; She Chen; Hongtao Yu
Journal:  Mol Cell       Date:  2004-11-05       Impact factor: 17.970

Review 3.  Bub1 and the multilayered inhibition of Cdc20-APC/C in mitosis.

Authors:  Vincent Vanoosthuyse; Kevin G Hardwick
Journal:  Trends Cell Biol       Date:  2005-05       Impact factor: 20.808

4.  Anaphase inactivation of the spindle checkpoint.

Authors:  William J Palframan; Janet B Meehl; Sue L Jaspersen; Mark Winey; Andrew W Murray
Journal:  Science       Date:  2006-07-06       Impact factor: 47.728

5.  Cdk and APC activities limit the spindle-stabilizing function of Fin1 to anaphase.

Authors:  Erika L Woodbury; David O Morgan
Journal:  Nat Cell Biol       Date:  2006-12-17       Impact factor: 28.824

6.  KEN-box-dependent degradation of the Bub1 spindle checkpoint kinase by the anaphase-promoting complex/cyclosome.

Authors:  Wei Qi; Hongtao Yu
Journal:  J Biol Chem       Date:  2006-12-11       Impact factor: 5.157

7.  Kinetochore microtubule dynamics and attachment stability are regulated by Hec1.

Authors:  Jennifer G DeLuca; Walter E Gall; Claudio Ciferri; Daniela Cimini; Andrea Musacchio; E D Salmon
Journal:  Cell       Date:  2006-12-01       Impact factor: 41.582

8.  Mad3 KEN boxes mediate both Cdc20 and Mad3 turnover, and are critical for the spindle checkpoint.

Authors:  Emma M J King; Sjaak J A van der Sar; Kevin G Hardwick
Journal:  PLoS One       Date:  2007-04-04       Impact factor: 3.240

9.  Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling.

Authors:  Yinghui Mao; Arshad Desai; Don W Cleveland
Journal:  J Cell Biol       Date:  2005-09-06       Impact factor: 10.539

10.  Cells satisfy the mitotic checkpoint in Taxol, and do so faster in concentrations that stabilize syntelic attachments.

Authors:  Zhenye Yang; Alison E Kenny; Daniela A Brito; Conly L Rieder
Journal:  J Cell Biol       Date:  2009-08-31       Impact factor: 10.539
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  17 in total

Review 1.  Monitoring the fidelity of mitotic chromosome segregation by the spindle assembly checkpoint.

Authors:  P Silva; J Barbosa; A V Nascimento; J Faria; R Reis; H Bousbaa
Journal:  Cell Prolif       Date:  2011-10       Impact factor: 6.831

2.  Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells.

Authors:  Reto Gassmann; Andrew J Holland; Dileep Varma; Xiaohu Wan; Filiz Civril; Don W Cleveland; Karen Oegema; Edward D Salmon; Arshad Desai
Journal:  Genes Dev       Date:  2010-05       Impact factor: 11.361

3.  Defining the molecular basis of BubR1 kinetochore interactions and APC/C-CDC20 inhibition.

Authors:  Sheena D'Arcy; Owen R Davies; Tom L Blundell; Victor M Bolanos-Garcia
Journal:  J Biol Chem       Date:  2010-03-10       Impact factor: 5.157

4.  Thyroid hormone receptor interacting protein 13 (TRIP13) AAA-ATPase is a novel mitotic checkpoint-silencing protein.

Authors:  Kexi Wang; Brianne Sturt-Gillespie; James C Hittle; Dawn Macdonald; Gordon K Chan; Tim J Yen; Song-Tao Liu
Journal:  J Biol Chem       Date:  2014-07-10       Impact factor: 5.157

5.  KNL1/Spc105 recruits PP1 to silence the spindle assembly checkpoint.

Authors:  Jessica S Rosenberg; Frederick R Cross; Hironori Funabiki
Journal:  Curr Biol       Date:  2011-06-07       Impact factor: 10.834

6.  Cyclin B3 and dynein heavy chain cooperate to increase fitness in the absence of mdf-1/MAD1 in Caenorhabditis elegans.

Authors:  Maja Tarailo-Graovac; Tammy Wong; Zhaozhao Qin; Stephane Flibotte; Jon Taylor; Donald G Moerman; Ann M Rose; Nansheng Chen
Journal:  Cell Cycle       Date:  2014       Impact factor: 4.534

7.  Caenorhabditis elegans cyclin B3 is required for multiple mitotic processes including alleviation of a spindle checkpoint-dependent block in anaphase chromosome segregation.

Authors:  Gary M R Deyter; Tokiko Furuta; Yasuhiro Kurasawa; Jill M Schumacher
Journal:  PLoS Genet       Date:  2010-11-24       Impact factor: 5.917

8.  Mathematical modeling of fission yeast Schizosaccharomyces pombe cell cycle: exploring the role of multiple phosphatases.

Authors:  P Anbumathi; Sharad Bhartiya; K V Venkatesh
Journal:  Syst Synth Biol       Date:  2011-12-08

9.  Proper cyclin B3 dosage is important for precision of metaphase-to-anaphase onset timing in Caenorhabditis elegans.

Authors:  Maja Tarailo-Graovac; Nansheng Chen
Journal:  G3 (Bethesda)       Date:  2012-08-01       Impact factor: 3.154

10.  A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B.

Authors:  Anna De Antoni; Stefano Maffini; Stefan Knapp; Andrea Musacchio; Stefano Santaguida
Journal:  J Cell Biol       Date:  2012-10-15       Impact factor: 10.539
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