Literature DB >> 1999346

Homozygous condition for a BrdU-requiring fragile site on chromosome 12.

I Voiculescu1, E Back, W Schempp.   

Abstract

A rare BrdU-sensitive fragile site, designated FRA12C*RQ24.2 has a relatively high frequency in the normal population. It can be demonstrated in a heterozygous and homozygous condition. There is no evidence that a phenotypic abnormality is associated with the expression of this site. A comparison with the fragile site FRA10B*RQ25.2 has revealed common features with FRA12C*RQ24.2.

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Year:  1991        PMID： 1999346     DOI： 10.1007/bf00201849

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  5 in total

1.  A BrdU-requiring fragile site on chromosome 12.

Authors:  I Voiculescu; C Hausmann; G Wolff; E Back
Journal:  Hum Genet       Date:  1988-02       Impact factor: 4.132

2.  New classes of common fragile sites induced by 5-azacytidine and bromodeoxyuridine.

Authors:  G R Sutherland; M I Parslow; E Baker
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

Review 3.  Report of the committee on cytogenetic markers.

Authors:  G R Sutherland; D H Ledbetter
Journal:  Cytogenet Cell Genet       Date:  1989

4.  Report of the committee on cytogenetic markers.

Authors:  G R Sutherland; J F Mattei
Journal:  Cytogenet Cell Genet       Date:  1987

5.  Heritable fragile sites on human chromosomes. VII. Children homozygous for the BrdU-requiring fra(10)(q25) are phenotypically normal.

Authors:  G R Sutherland
Journal:  Am J Hum Genet       Date:  1981-11       Impact factor: 11.025
  5 in total
  2 in total

Review 1.  Fragility Extraordinaire: Unsolved Mysteries of Chromosome Fragile Sites.

Authors:  Wenyi Feng; Arijita Chakraborty
Journal:  Adv Exp Med Biol       Date:  2017       Impact factor: 2.622

Review 2.  Are common fragile sites merely structural domains or highly organized "functional" units susceptible to oncogenic stress?

Authors:  Alexandros G Georgakilas; Petros Tsantoulis; Athanassios Kotsinas; Ioannis Michalopoulos; Paul Townsend; Vassilis G Gorgoulis
Journal:  Cell Mol Life Sci       Date:  2014-09-20       Impact factor: 9.261
  2 in total

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