Literature DB >> 19913938

Biomedical question answering: a survey.

Sofia J Athenikos1, Hyoil Han.   

Abstract

OBJECTIVES: In this survey, we reviewed the current state of the art in biomedical QA (Question Answering), within a broader framework of semantic knowledge-based QA approaches, and projected directions for the future research development in this critical area of intersection between Artificial Intelligence, Information Retrieval, and Biomedical Informatics.
MATERIALS AND METHODS: We devised a conceptual framework within which to categorize current QA approaches. In particular, we used "semantic knowledge-based QA" as a category under which to subsume QA techniques and approaches, both corpus-based and knowledge base (KB)-based, that utilize semantic knowledge-informed techniques in the QA process, and we further classified those approaches into three subcategories: (1) semantics-based, (2) inference-based, and (3) logic-based. Based on the framework, we first conducted a survey of open-domain or non-biomedical-domain QA approaches that belong to each of the three subcategories. We then conducted an in-depth review of biomedical QA, by first noting the characteristics of, and resources available for, biomedical QA and then reviewing medical QA approaches and biological QA approaches, in turn. The research articles reviewed in this paper were found and selected through online searches.
RESULTS: Our review suggested the following tasks ahead for the future research development in this area: (1) Construction of domain-specific typology and taxonomy of questions (biological QA), (2) Development of more sophisticated techniques for natural language (NL) question analysis and classification, (3) Development of effective methods for answer generation from potentially conflicting evidences, (4) More extensive and integrated utilization of semantic knowledge throughout the QA process, and (5) Incorporation of logic and reasoning mechanisms for answer inference.
CONCLUSION: Corresponding to the growth of biomedical information, there is a growing need for QA systems that can help users better utilize the ever-accumulating information. Continued research toward development of more sophisticated techniques for processing NL text, for utilizing semantic knowledge, and for incorporating logic and reasoning mechanisms, will lead to more useful QA systems. Copyright 2009 Elsevier Ireland Ltd. All rights reserved.

Mesh:

Year:  2009        PMID: 19913938     DOI: 10.1016/j.cmpb.2009.10.003

Source DB:  PubMed          Journal:  Comput Methods Programs Biomed        ISSN: 0169-2607            Impact factor:   5.428


  24 in total

1.  The MiPACQ clinical question answering system.

Authors:  Brian L Cairns; Rodney D Nielsen; James J Masanz; James H Martin; Martha S Palmer; Wayne H Ward; Guergana K Savova
Journal:  AMIA Annu Symp Proc       Date:  2011-10-22

2.  Leveraging medical thesauri and physician feedback for improving medical literature retrieval for case queries.

Authors:  Parikshit Sondhi; Jimeng Sun; ChengXiang Zhai; Robert Sorrentino; Martin S Kohn
Journal:  J Am Med Inform Assoc       Date:  2012-03-21       Impact factor: 4.497

3.  Combining Open-domain and Biomedical Knowledge for Topic Recognition in Consumer Health Questions.

Authors:  Yassine Mrabet; Halil Kilicoglu; Kirk Roberts; Dina Demner-Fushman
Journal:  AMIA Annu Symp Proc       Date:  2017-02-10

4.  A Semantic Parsing Method for Mapping Clinical Questions to Logical Forms.

Authors:  Kirk Roberts; Braja Gopal Patra
Journal:  AMIA Annu Symp Proc       Date:  2018-04-16

5.  Annotating Logical Forms for EHR Questions.

Authors:  Kirk Roberts; Dina Demner-Fushman
Journal:  LREC Int Conf Lang Resour Eval       Date:  2016-05

6.  Automated identification of molecular effects of drugs (AIMED).

Authors:  Safa Fathiamini; Amber M Johnson; Jia Zeng; Alejandro Araya; Vijaykumar Holla; Ann M Bailey; Beate C Litzenburger; Nora S Sanchez; Yekaterina Khotskaya; Hua Xu; Funda Meric-Bernstam; Elmer V Bernstam; Trevor Cohen
Journal:  J Am Med Inform Assoc       Date:  2016-04-23       Impact factor: 4.497

7.  Using FHIR to Construct a Corpus of Clinical Questions Annotated with Logical Forms and Answers.

Authors:  Sarvesh Soni; Meghana Gudala; Daisy Zhe Wang; Kirk Roberts
Journal:  AMIA Annu Symp Proc       Date:  2020-03-04

8.  Textual inference for eligibility criteria resolution in clinical trials.

Authors:  Chaitanya Shivade; Courtney Hebert; Marcelo Lopetegui; Marie-Catherine de Marneffe; Eric Fosler-Lussier; Albert M Lai
Journal:  J Biomed Inform       Date:  2015-09-14       Impact factor: 6.317

Review 9.  Usability survey of biomedical question answering systems.

Authors:  Michael A Bauer; Daniel Berleant
Journal:  Hum Genomics       Date:  2012-09-01       Impact factor: 4.639

10.  Assisted knowledge discovery for the maintenance of clinical guidelines.

Authors:  Emilie Pasche; Patrick Ruch; Douglas Teodoro; Angela Huttner; Stephan Harbarth; Julien Gobeill; Rolf Wipfli; Christian Lovis
Journal:  PLoS One       Date:  2013-04-30       Impact factor: 3.240

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