OBJECTIVES: To examine our retrospective data on the outcomes of intracytoplasmic sperm injection (ICSI) and to determine whether a history of varicocele repair in men with nonobstructive azoospermia (NOA) undergoing an ICSI cycle was optimizing or not. METHODS: This retrospective study was conducted on Baskent University Department of Obstetrics and Gynecology, IVF Unit, and Department of Urology. Infertile couples suffering from NOA scheduled to an ICSI cycle, which was controlled ovarian hyperstimulation with a gonadotropin or gonadotrophin-releasing hormone-agonist protocol, selected for the study were divided into 2 groups: group 1 (n = 31) included NOA patients who had undergone prior varicocele repair, and group 2 (n = 65) included NOA patients who had not undergone varicocele repair. RESULTS: There was a significant difference between the 2 groups considering the sperm retrieval rate, which was higher in the varicocele repair group (sperm retrieval rate 60.81% and 38.46% respectively, P = .01). The clinical pregnancy rate and live birth rate were significantly higher in the varicocelectomy group (74.2% vs 52.3% and 64.5% vs 41.5%, respectively, P <.05). CONCLUSIONS: Varicocele repair in NOA might be considered in patients undergoing ICSI cycle. 2010 Elsevier Inc. All rights reserved.
OBJECTIVES: To examine our retrospective data on the outcomes of intracytoplasmic sperm injection (ICSI) and to determine whether a history of varicocele repair in men with nonobstructive azoospermia (NOA) undergoing an ICSI cycle was optimizing or not. METHODS: This retrospective study was conducted on Baskent University Department of Obstetrics and Gynecology, IVF Unit, and Department of Urology. Infertile couples suffering from NOA scheduled to an ICSI cycle, which was controlled ovarian hyperstimulation with a gonadotropin or gonadotrophin-releasing hormone-agonist protocol, selected for the study were divided into 2 groups: group 1 (n = 31) included NOA patients who had undergone prior varicocele repair, and group 2 (n = 65) included NOA patients who had not undergone varicocele repair. RESULTS: There was a significant difference between the 2 groups considering the sperm retrieval rate, which was higher in the varicocele repair group (sperm retrieval rate 60.81% and 38.46% respectively, P = .01). The clinical pregnancy rate and live birth rate were significantly higher in the varicocelectomy group (74.2% vs 52.3% and 64.5% vs 41.5%, respectively, P <.05). CONCLUSIONS: Varicocele repair in NOA might be considered in patients undergoing ICSI cycle. 2010 Elsevier Inc. All rights reserved.
Authors: Matthew A Will; Jason Swain; Mikkel Fode; Jens Sonksen; Gregory M Christman; Dana Ohl Journal: Fertil Steril Date: 2011-01-26 Impact factor: 7.329
Authors: S D'Andrea; A V Giordano; S Carducci; L Sacchetti; S Necozione; M Costanzo; A De Gregorio; A Micillo; F Francavilla; S Francavilla; A Barbonetti Journal: J Endocrinol Invest Date: 2015-03-05 Impact factor: 4.256
Authors: Adithya Balasubramanian; Nannan Thirumavalavan; Jason M Scovell; Jonathan Lo; Byung Ji; Elizabeth L Godfrey; Alexander W Pastuszak; Larry I Lipshultz Journal: Urology Date: 2018-10-23 Impact factor: 2.649