OBJECTIVE: To evaluate the current literature on the impact and potential mechanisms of varicocele repair on male fertility. DESIGN: Pertinent articles were identified through computer PubMed search on varicocele repair and male factor infertility. References of selected articles were hand searched for additional citations. CONCLUSION(S): Varicocele repair has been shown to reverse a spectrum of effects contributing to men with impaired fertility. Clinical studies on the intervention have illustrated variable effects on postoperative sperm parameters and pregnancy rates (PR). Studies with conflicting results suffer from a significant number of confounding variables such as variable repair technique or lack of controls. Additional studies are warranted on the role of modern microsurgical varicocelectomy given the improvements in assisted reproductive technologies (ART).
OBJECTIVE: To evaluate the current literature on the impact and potential mechanisms of varicocele repair on male fertility. DESIGN: Pertinent articles were identified through computer PubMed search on varicocele repair and male factor infertility. References of selected articles were hand searched for additional citations. CONCLUSION(S): Varicocele repair has been shown to reverse a spectrum of effects contributing to men with impaired fertility. Clinical studies on the intervention have illustrated variable effects on postoperative sperm parameters and pregnancy rates (PR). Studies with conflicting results suffer from a significant number of confounding variables such as variable repair technique or lack of controls. Additional studies are warranted on the role of modern microsurgical varicocelectomy given the improvements in assisted reproductive technologies (ART).
Authors: Simon Freeman; Michele Bertolotto; Jonathan Richenberg; Jane Belfield; Vikram Dogra; Dean Y Huang; Francesco Lotti; Karolina Markiet; Olivera Nikolic; Subramaniyan Ramanathan; Parvati Ramchandani; Laurence Rocher; Mustafa Secil; Paul S Sidhu; Katarzyna Skrobisz; Michal Studniarek; Athina Tsili; Ahmet Tuncay Turgut; Pietro Pavlica; Lorenzo E Derchi Journal: Eur Radiol Date: 2019-07-22 Impact factor: 5.315
Authors: M Zavattaro; C Ceruti; G Motta; S Allasia; L Marinelli; C Di Bisceglie; M P Tagliabue; M Sibona; L Rolle; F Lanfranco Journal: J Endocrinol Invest Date: 2018-10-03 Impact factor: 4.256
Authors: J C Trussell; Gregory M Christman; Dana A Ohl; Richard S Legro; Stephen A Krawetz; Peter J Snyder; Pasquale Patrizio; Alex J Polotsky; Michael P Diamond; Peter R Casson; Christos Coutifaris; Kurt Barnhart; Robert G Brzyski; William D Schlaff; Randall Meacham; David Shin; Tracey Thomas; Meizhuo Zhang; Nanette Santoro; Esther Eisenberg; Heping Zhang Journal: Fertil Steril Date: 2011-12 Impact factor: 7.329